Atypical sporadic CJD-MM phenotype with white matter kuru plaques associated with intranuclear inclusion body and argyrophilic grain disease

2015 ◽  
Vol 35 (4) ◽  
pp. 336-342 ◽  
Author(s):  
Anna S. Berghoff ◽  
Anita Trummert ◽  
Ursula Unterberger ◽  
Thomas Ströbel ◽  
Tibor Hortobágyi ◽  
...  
Keyword(s):  
White Matter ◽  
Inclusion Body ◽  
Intranuclear Inclusion ◽  
Argyrophilic Grain Disease ◽  
Argyrophilic Grain ◽  
Sporadic Cjd ◽  
Kuru Plaques

scholarly journals Argyrophilic grain disease: An underestimated tauopathy

2015 ◽  
Vol 9 (1) ◽  
pp. 2-8 ◽  
Author(s):  
Roberta Diehl Rodriguez ◽  
Lea Tenenholz Grinberg
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Defense Mechanism ◽  
Neuropsychiatric Symptoms ◽  
Argyrophilic Grain Disease ◽  
Coiled Bodies ◽  
Pathologic Features ◽  
High Prevalence ◽  
Argyrophilic Grain ◽  
Argyrophilic Grains

Argyrophilic grain disease (AGD) is an under-recognized, distinct, highly frequent sporadic tauopathy, with a prevalence reaching 31.3% in centenarians. The most common AGD manifestation is slowly progressive amnestic mild cognitive impairment, accompanied by a high prevalence of neuropsychiatric symptoms. AGD diagnosis can only be achieved postmortem based on the finding of its three main pathologic features: argyrophilic grains, oligodendrocytic coiled bodies and neuronal pretangles. AGD is frequently seen together with Alzheimer's disease-type pathology or in association with other neurodegenerative diseases. Recent studies suggest that AGD may be a defense mechanism against the spread of other neuropathological entities, particularly Alzheimer's disease. This review aims to provide an in-depth overview of the current understanding on AGD.

Brain Dopamine and Other Neurotransmitters in Neuronal Intranuclear Inclusion Body Disorder

1986 ◽  
pp. 477-478
Author(s):  
S. J. Kish ◽  
J. J. Gilbert ◽  
L. J. Chang ◽  
L. M. Mirchandani ◽  
K. S. Shannak ◽  
...  
Keyword(s):  
Inclusion Body ◽  
Brain Dopamine ◽  
Intranuclear Inclusion ◽  
Neuronal Intranuclear Inclusion

scholarly journals Erratum

2012 ◽  
Vol 24 (1) ◽  
pp. 246-246
Keyword(s):  
Virus Infection ◽  
Inclusion Body ◽  
Pseudorabies Virus ◽  
Intranuclear Inclusion ◽  
Hunting Dogs ◽  
Intracytoplasmic Inclusion ◽  
Intracytoplasmic Inclusion Body

JVDI 23:915–923 (September 2011) In the article entitled “Pseudorabies virus infection in Oklahoma hunting dogs” by Sarah D. Cramer et al., on page 918 in the legend to Figure 2, the legend should refer to an “intranuclear” inclusion body instead of an “intracytoplasmic” inclusion body.

scholarly journals Molecular evolution and genetics of the Saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease

2004 ◽  
Vol 89 (1) ◽  
pp. 179-188 ◽  
Author(s):  
Chris Conrad ◽  
Cintia Vianna ◽  
Christian Schultz ◽  
Dietmar R. Thal ◽  
Estifanos Ghebremedhin ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Molecular Evolution ◽  
Argyrophilic Grain Disease ◽  
Argyrophilic Grain

P3-186 Concurrent Alzheimer's disease-related pathology lowers the threshold for developing dementia in argyrophilic grain disease

2004 ◽  
Vol 25 ◽  
pp. S408-S409
Author(s):  
Dietmar R. Thal ◽  
Christian Schultz ◽  
Giovannina Botez ◽  
Mrak E. Robert ◽  
Sue T. Griffin ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Argyrophilic Grain Disease ◽  
Argyrophilic Grain
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