Effectiveness of Low‐Frequency Pallidal Deep Brain Stimulation at 65 Hz in Tourette Syndrome

Author(s):  
Fengqiao Sun ◽  
Xiaohua Zhang ◽  
Sheng Dong ◽  
Yuqing Zhang ◽  
Jiping Li ◽  
...  
2013 ◽  
Vol 260 (9) ◽  
pp. 2417-2419 ◽  
Author(s):  
João Massano ◽  
Cláudia Sousa ◽  
Tom Foltynie ◽  
Ludvic Zrinzo ◽  
Marwan Hariz ◽  
...  

2019 ◽  
Vol 69 ◽  
pp. 14-18
Author(s):  
Davide Cappon ◽  
Mazda Beigi ◽  
Zinovia Kefalopoulou ◽  
Ludvic Zrinzo ◽  
Joseph Candelario ◽  
...  

2021 ◽  
Vol 11 (4) ◽  
pp. 461
Author(s):  
Francesca Morreale ◽  
Zinovia Kefalopoulou ◽  
Ludvic Zrinzo ◽  
Patricia Limousin ◽  
Eileen Joyce ◽  
...  

As part of the first randomized double-blind trial of deep brain stimulation (DBS) of the globus pallidus (GPi) in Tourette syndrome, we examined the effect of stimulation on response initiation and inhibition. A total of 14 patients with severe Tourette syndrome were recruited and tested on the stop signal task prior to and after GPi-DBS surgery and compared to eight age-matched healthy controls. Tics were significantly improved following GPi-DBS. The main measure of reactive inhibition, the stop signal reaction time did not change from before to after surgery and did not differ from that of healthy controls either before or after GPi-DBS surgery. This suggests that patients with Tourette syndrome have normal reactive inhibition which is not significantly altered by GPi-DBS.


Sign in / Sign up

Export Citation Format

Share Document