scholarly journals Investigation of Deep Brain Stimulation Mechanisms During Implantable Pulse Generator Replacement Surgery

2013 ◽  
Vol 17 (5) ◽  
pp. 419-424 ◽  
Author(s):  
Brandon D. Swan ◽  
Warren M. Grill ◽  
Dennis A. Turner
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Pulse Generator ◽  
Implantable Pulse Generator ◽  
Replacement Surgery ◽  
Deep Brain ◽  
Generator Replacement

Reoperation for device infection and erosion following deep brain stimulation implantable pulse generator placement

2020 ◽  
Vol 133 (2) ◽  
pp. 403-410 ◽  
Author(s):  
Travis J. Atchley ◽  
Nicholas M. B. Laskay ◽  
Brandon A. Sherrod ◽  
A. K. M. Fazlur Rahman ◽  
Harrison C. Walker ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Movement Disorders ◽  
Pulse Generator ◽  
Rank Test ◽  
Implantable Pulse Generator ◽  
Device Infection ◽  
Deep Brain

OBJECTIVEInfection and erosion following implantable pulse generator (IPG) placement are associated with morbidity and cost for patients with deep brain stimulation (DBS) systems. Here, the authors provide a detailed characterization of infection and erosion events in a large cohort that underwent DBS surgery for movement disorders.METHODSThe authors retrospectively reviewed consecutive IPG placements and replacements in patients who had undergone DBS surgery for movement disorders at the University of Alabama at Birmingham between 2013 and 2016. IPG procedures occurring before 2013 in these patients were also captured. Descriptive statistics, survival analyses, and logistic regression were performed using generalized linear mixed effects models to examine risk factors for the primary outcomes of interest: infection within 1 year or erosion within 2 years of IPG placement.RESULTSIn the study period, 384 patients underwent a total of 995 IPG procedures (46.4% were initial placements) and had a median follow-up of 2.9 years. Reoperation for infection occurred after 27 procedures (2.7%) in 21 patients (5.5%). No difference in the infection rate was observed for initial placement versus replacement (p = 0.838). Reoperation for erosion occurred after 16 procedures (1.6%) in 15 patients (3.9%). Median time to reoperation for infection and erosion was 51 days (IQR 24–129 days) and 149 days (IQR 112–285 days), respectively. Four patients with infection (19.0%) developed a second infection requiring a same-side reoperation, two of whom developed a third infection. Intraoperative vancomycin powder was used in 158 cases (15.9%) and did not decrease the infection risk (infected: 3.2% with vancomycin vs 2.6% without, p = 0.922, log-rank test). On logistic regression, a previous infection increased the risk for infection (OR 35.0, 95% CI 7.9–156.2, p < 0.0001) and a lower patient BMI was a risk factor for erosion (BMI ≤ 24 kg/m2: OR 3.1, 95% CI 1.1–8.6, p = 0.03).CONCLUSIONSIPG-related infection and erosion following DBS surgery are uncommon but clinically significant events. Their respective timelines and risk factors suggest different etiologies and thus different potential corrective procedures.

scholarly journals Patient Experience with Rechargeable Implantable Pulse Generator Deep Brain Stimulation for Movement Disorders

2019 ◽  
Vol 97 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Kyle T. Mitchell ◽  
Monica Volz ◽  
Aaron Lee ◽  
Marta San Luciano ◽  
Sarah Wang ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Patient Experience ◽  
Brain Stimulation ◽  
Movement Disorders ◽  
Pulse Generator ◽  
Implantable Pulse Generator ◽  
Deep Brain

Replacement of a deep brain stimulation implantable pulse generator with a rechargeable device

2014 ◽  
Vol 18 (3) ◽  
pp. 140-142
Author(s):  
Danny Tat-Ming Chan ◽  
Xian-Lun Zhu ◽  
Claire Ka-Yee Lau ◽  
Rosanna Kit-Man Wong ◽  
Wai-Sang Poon
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Pulse Generator ◽  
Implantable Pulse Generator ◽  
Deep Brain
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