scholarly journals Oral/oesophageal candidiasis is a risk factor for severe infection after kidney transplantation

Nephrology ◽  
2021 ◽  
Author(s):  
Tetsuya Abe ◽  
Kenta Futamura ◽  
Norihiko Goto ◽  
Kiyomi Ohara ◽  
Taiki Ogasa ◽  
...  
2008 ◽  
Vol 21 (9) ◽  
pp. 873-878 ◽  
Author(s):  
Juan Torres ◽  
Jose María Aguado ◽  
Rafael San Juan ◽  
Amado Andrés ◽  
Prado Sierra ◽  
...  

2014 ◽  
Vol 46 (2) ◽  
pp. 537-539 ◽  
Author(s):  
K. Tokodai ◽  
N. Amada ◽  
I. Haga ◽  
T. Takayama ◽  
A. Nakamura ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250829
Author(s):  
Nancy Perrottet ◽  
Mario Fernández-Ruiz ◽  
Isabelle Binet ◽  
Michael Dickenmann ◽  
Suzan Dahdal ◽  
...  

Acute antibody-mediated rejection (AMR) remains a challenge after kidney transplantation (KT). As there is no clear-cut treatment recommendation, accurate information on current therapeutic strategies in real-life practice is needed. KT recipients from the multicenter Swiss Transplant Cohort Study treated for acute AMR during the first post-transplant year were included retrospectively. We aimed at describing the anti-rejection protocols used routinely, as well as patient and graft outcomes, with focus on infectious complications. Overall, 65/1669 (3.9%) KT recipients were treated for 75 episodes of acute AMR. In addition to corticosteroid boluses, most common therapies included plasmapheresis (56.0%), intravenous immunoglobulins (IVIg) (38.7%), rituximab (25.3%), and antithymocyte globulin (22.7%). At least one infectious complication occurred within 6 months from AMR treatment in 63.6% of patients. Plasmapheresis increased the risk of overall (hazard ratio [HR]: 2.89; P-value = 0.002) and opportunistic infection (HR: 5.32; P-value = 0.033). IVIg exerted a protective effect for bacterial infection (HR: 0.29; P-value = 0.053). The recovery of renal function was complete at 3 months after AMR treatment in 67% of episodes. One-year death-censored graft survival was 90.9%. Four patients (6.2%) died during the first year (two due to severe infection). In this nationwide cohort we found significant heterogeneity in therapeutic approaches for acute AMR. Infectious complications were common, particularly among KT recipients receiving plasmapheresis.


Author(s):  
Mohsen Aliakbarian ◽  
Rozita Khodashahi ◽  
Mahin Ghorban Sabbagh ◽  
Hamid Reza Naderi ◽  
Mandana Khodashahi ◽  
...  

Background: Transplant recipients are at high risk for severe Coronavirus disease-2019 (COVID-19). Transplant recipients are immune-compromised individuals at high risk for severe infection. This study aimed to compare the presentations and outcomes of liver and kidney transplant recipients who were infected with COVID-19 in the Iranian population. Methods: This cross-sectional study was conducted at Imam Reza and Montaserieh Hospitals affiliated with Mashhad University of Medical Sciences, Mashhad, Iran, between 2020 and 2021. In general, 52 patients were selected and divided into two groups of the kidney (n=28) and liver (n=24) transplantation. Two groups were compared in terms of demographic characteristics and clinical findings. Results: Of 52 patients, severe COVID-19 infection was reported in 61% of the patients. There was no significant difference between the two groups in terms of symptoms, except for cough (χ2=8.09; P=0.004), clinical condition, and laboratory symptoms, except for creatinine (Z=14; P<0.005), alkaline phosphatase (Z=4.55; P=0.03), total bilirubin (Z=8.93; P=0.03), and partial thromboplastin time (Z=5.97; P=0.01). There was no relationship between the outcome and the use of immunosuppressive medications (P>0.05). All patients with kidney transplantation survived, while two cases in the liver transplantation group failed to survive (χ2=2.42; P=0.11). Conclusion: The mortality rate was higher in the liver transplant recipients, compared to the patients who underwent kidney transplantation.


2018 ◽  
Vol 102 ◽  
pp. S359 ◽  
Author(s):  
Javier Carbone ◽  
Maria Luisa Rodriguez-Ferrero ◽  
Marcos Lopez-Hoyos ◽  
Boris Karanovic ◽  
Manuel Arias ◽  
...  

2017 ◽  
Vol 34 (8) ◽  
pp. 1067-1073 ◽  
Author(s):  
S. Johal ◽  
F. Jackson-Spence ◽  
H. Gillott ◽  
S. Tahir ◽  
J. Mytton ◽  
...  

2015 ◽  
Vol 28 (11) ◽  
pp. 1276-1282 ◽  
Author(s):  
Josep M. Cruzado ◽  
Anna Manonelles ◽  
Helena Vila ◽  
Edoardo Melilli ◽  
Neus Sala ◽  
...  

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