Acute kidney injury in critically ill surgical patients: Epidemiology, risk factors and outcomes

Nephrology ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Konlawij Trongtrakul ◽  
Chaiwut Sawawiboon ◽  
Amanda Y Wang ◽  
Anusang Chitsomkasem ◽  
Ploynapas Limphunudom ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Critically Ill ◽  
Kidney Injury ◽  
Surgical Patients ◽  
Critically Ill Surgical Patients

Late Initiation of Continuous Veno-Venous Hemofiltration Therapy is Associated with a Lower Survival Rate in Surgical Critically Ill Patients with Postoperative Acute Kidney Injury

2012 ◽  
Vol 78 (2) ◽  
pp. 235-242 ◽  
Author(s):  
Shih-Chi Wu ◽  
Chih-Yuan Fu ◽  
Hsin-Hung Lin ◽  
Ray-Jade Chen ◽  
Chi-Hsun Hsieh ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Critically Ill ◽  
Kidney Injury ◽  
Surgical Patients ◽  
Lower Survival Rate ◽  
Late Initiation ◽  
Late Group ◽  
Critically Ill Surgical Patients

There is controversy about the appropriate timing for renal replacement therapy in patients with acute kidney injury (AKI). We are interested in the appropriate timing for initiation of continuous renal replacement therapy in critically ill surgical patients with postoperative acute kidney injury. Seventy-three critically ill surgical patients with postoperative AKI who received continuous renal replacement therapy (CRRT) were enrolled. Indications for CRRT were: 1) AKI with hyperkalemia, 2) metabolic acidosis, 3) pulmonary edema refractory to diuretics, and 4) oliguria with progressive azotemia, especially in unstable hemodynamics. Using RIFLE (Risk, Injury, Failure, Loss, End stage) classification, patients who received CRRT in the “Risk” stage were defined as early group, whereas those in the “Injury/ Failure” stage were labeled as late group. We used continuous veno-venous hemofiltration as CRRT in this series. There were 20 patients in the early group and 53 patients in the late group. The mean ages were 61.5 ± 21.8 years versus 60.8 ± 17.5 years. The mortality rate was 50 per cent versus 84.9 per cent. There were no significant differences in demographic characteristics or type of surgery or physiological scores. Our data show that late initiation of CRRT is associated with a lower survival rate in critically ill surgical patients with postoperative AKI; however, further studies are required.

Epidemiology and outcomes of acute kidney injury in critically ill surgical patients

2015 ◽  
Vol 30 (1) ◽  
pp. 102-106 ◽  
Author(s):  
Donald G. Harris ◽  
Michelle P. McCrone ◽  
Grace Koo ◽  
Adam S. Weltz ◽  
William C. Chiu ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Critically Ill ◽  
Kidney Injury ◽  
Surgical Patients ◽  
Critically Ill Surgical Patients

scholarly journals External Validation of the Acute Kidney Injury Risk Prediction Score for Critically Ill Surgical Patients Who Underwent Major Non-Cardiothoracic Surgery

Healthcare ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 209
Author(s):  
Konlawij Trongtrakul ◽  
Jayanton Patumanond ◽  
Piyarat Phairatwet ◽  
Chaiwut Sawawiboon ◽  
Anusang Chitsomkasem ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Critically Ill ◽  
External Validation ◽  
Kidney Injury ◽  
Cardiothoracic Surgery ◽  
Clinical Usefulness ◽  
Prediction Score ◽  
Surgical Patients ◽  
Discriminative Ability ◽  
Critically Ill Surgical Patients

Background: Acute kidney injury (AKI) is a common complication encountered in an intensive care unit (ICU). In 2020, the AKI prediction score was developed specifically for critically ill surgical patients who underwent major non-cardiothoracic surgeries. This study aimed to externally validate the AKI prediction score in terms of performance and clinical utility. Methods: External validation was carried out in a prospective cohort of patients admitted to the ICU of the Faculty of Medicine Vajira Hospital between September 2014 and September 2015. The endpoint was AKI within seven days following ICU admission. Discriminative ability was based on the area under the receiver operating characteristic curves (AuROC). Calibration and clinical usefulness were evaluated. Results: A total of 201 patients were included in the analysis. AKI occurred in 37 (18.4%) patients. The discriminative ability dropped from good in the derivation cohort, to acceptable in the validation cohort (0.839 (95%CI 0.825–0.852) vs. 0.745 (95%CI 0.652–0.838)). No evidence of lack-of-fit was identified (p = 0.754). The score had potential clinical usefulness across the range of threshold probability from 10 to 50%. Conclusions: The AKI prediction score showed an acceptable discriminative performance and calibration with potential clinical usefulness for predicting AKI risk in surgical patients who underwent major non-cardiothoracic surgery.

Acute Kidney Injury in Critically Ill Surgical Patients: a Cohort Study

2014 ◽  
Vol 186 (2) ◽  
pp. 584-585
Author(s):  
D.G. Harris ◽  
G. Koo ◽  
M.P. McCrone ◽  
W.C. Chiu ◽  
T.M. Scalea ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cohort Study ◽  
Critically Ill ◽  
Kidney Injury ◽  
Surgical Patients ◽  
Critically Ill Surgical Patients

scholarly journals Acute kidney injury risk prediction score for critically-ill surgical patients

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Konlawij Trongtrakul ◽  
Jayanton Patumanond ◽  
Suneerat Kongsayreepong ◽  
Sunthiti Morakul ◽  
Tanyong Pipanmekaporn ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Critically Ill ◽  
Risk Prediction ◽  
Injury Risk ◽  
Kidney Injury ◽  
Prediction Score ◽  
Surgical Patients ◽  
Critically Ill Surgical Patients

Risk Factors of Acute Kidney Injury in Critically Ill Children*

2016 ◽  
Vol 17 (9) ◽  
pp. e391-e398 ◽  
Author(s):  
Morgan B. Slater ◽  
Andrea Gruneir ◽  
Paula A. Rochon ◽  
Andrew W. Howard ◽  
Gideon Koren ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Critically Ill ◽  
Kidney Injury ◽  
Critically Ill Children
Sign in / Sign up

Export Citation Format

Share Document