Prospective associations between environmental heavy metal exposure and renal outcomes in adults with chronic kidney disease

Nephrology ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 830-836 ◽  
Author(s):  
Chun-Chieh Tsai ◽  
Chia-Lin Wu ◽  
Chew-Teng Kor ◽  
Ie-Bin Lian ◽  
Chin-Hua Chang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Heavy Metal ◽  
Kidney Disease ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Renal Outcomes

scholarly journals Environmental Heavy Metal Exposure and Chronic Kidney Disease in the General Population

2015 ◽  
Vol 30 (3) ◽  
pp. 272 ◽  
Author(s):  
Nam Hee Kim ◽  
Young Youl Hyun ◽  
Kyu-Beck Lee ◽  
Yoosoo Chang ◽  
Seungho Rhu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Heavy Metal ◽  
Kidney Disease ◽  
General Population ◽  
Metal Exposure ◽  
Heavy Metal Exposure

scholarly journals Erratum: Environmental Heavy Metal Exposure and Chronic Kidney Disease in the General Population

2015 ◽  
Vol 30 (4) ◽  
pp. 507
Author(s):  
Nam Hee Kim ◽  
Young Youl Hyun ◽  
Kyu-Beck Lee ◽  
Yoosoo Chang ◽  
Seungho Ryu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Heavy Metal ◽  
Kidney Disease ◽  
General Population ◽  
Metal Exposure ◽  
Heavy Metal Exposure

Bioaccessibility-corrected health risk of heavy metal exposure via shellfish consumption in coastal region of China

2021 ◽  
Vol 273 ◽  
pp. 116529
Author(s):  
Minwei Chai ◽  
Ruili Li ◽  
Yuan Gong ◽  
Xiaoxue Shen ◽  
Lingyun Yu
Keyword(s):  
Heavy Metal ◽  
Health Risk ◽  
Coastal Region ◽  
Metal Exposure ◽  
Heavy Metal Exposure

scholarly journals Relationship between heavy metal exposure and type 2 diabetes: a large-scale retrospective cohort study using occupational health examinations

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e039541
Author(s):  
Jun Ho Ji ◽  
Mi Hyeon Jin ◽  
Jung-Hun Kang ◽  
Soon Il Lee ◽  
Suee Lee ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Type 2 Diabetes ◽  
Heavy Metal ◽  
Cohort Study ◽  
Retrospective Cohort ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Lead And Cadmium

ObjectivesTo investigate the associations between heavy metal exposure and serum ferritin levels, physical measurements and type 2 diabetes mellitus (DM).DesignA retrospective cohort study.SettingChangwon, the location of this study, is a Korean representative industrial city. Data were obtained from medical check-ups between 2002 and 2018.ParticipantsA total of 34 814 male subjects were included. Of them, 1035 subjects with lead exposure, 200 subjects with cadmium exposure and the 33 579 remaining were assigned to cohort A, cohort B and the control cohort, respectively. Data including personal history of alcohol and smoking, age, height, weight, the follow-up duration, haemoglobin A1c (HbA1c), fasting blood sugar (FBS), ferritin levels, and lead and cadmium levels within 1 year after exposure were collected.Primary outcome measureIn subjects without diabetes, changes in FBS and HbA1c were analysed through repeated tests at intervals of 1 year or longer after the occupational exposure to heavy metals.ResultsIn Cohort A, DM was diagnosed in 33 subjects. There was a significant difference in lead concentrations between the subjects diagnosed with DM and those without DM during the follow-up period (3.94±2.92 mg/dL vs 2.81±2.03 mg/dL, p=0.002). Simple exposure to heavy metals (lead and cadmium) was not associated with DM in Cox regression models (lead exposure (HR) 1.01, 95% CI: 0.58 to 1.77, p 0.971; cadmium exposure HR 1.48, 95% CI: 0.61 to 3.55, p=0.385). Annual changes in FBS according to lead concentration at the beginning of exposure showed a positive correlation (r=0.072, p=0.032).ConclusionOur findings demonstrated that simple occupational exposure to heavy metals lead and cadmium was not associated with the incidence of DM. However, lead concentrations at the beginning of the exposure might be an indicator of DM and glucose elevations.

scholarly journals Low serum calcium is associated with poor renal outcomes in chronic kidney disease stages 3–4 patients

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Lee-Moay Lim ◽  
Hung-Tien Kuo ◽  
Mei-Chuan Kuo ◽  
Yi-Wen Chiu ◽  
Jia-Jung Lee ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Serum Calcium ◽  
Renal Outcomes ◽  
Disease Stages ◽  
Low Serum

scholarly journals Heavy metal concentrations in the edible portions of Centella asiatica: Health risk toward chronic kidney disease of uncertain etiology

2021 ◽  
Vol 3 (6) ◽  
Author(s):  
W. M. Dimuthu Nilmini Wijeyaratne ◽  
Ellewaththe Arachchilage Charuni Se Kumari
Keyword(s):  
Chronic Kidney Disease ◽  
Heavy Metal ◽  
Kidney Disease ◽  
Health Risk ◽  
Health Risks ◽  
Hazard Index ◽  
Organic Matter Content ◽  
Centella Asiatica ◽  
Consumer Safety ◽  
Uncertain Etiology

AbstractCentella asiatica is a commonly consumed green leafy vegetable in many developing countries due its high nutritious value and availability at low cost. The present study was conducted to assess the Cd, Cr and Pb uptake associated health risks of Centella asiatica harvested from organic and non-organic cultivations in a chronic kidney disease of uncertain etiology (CKDue) prevalent area in Sri Lanka. The health risk assessment was conducted in terms of the bioconcentration factor (BCF), soil-to-root and root-to-leaf translocation factors ($${\text{TF}}\,({\text{soil-root}})$$ TF ( soil-root ) and $${\text{TF}}\,({\text{root-leaf}})$$ TF ( root-leaf ) ), Target hazard quotient for each heavy metal (THQ) and hazard index (HI). In addition, the spatial variation of physical and chemical parameters of the root zone soil were assessed using MINITAB 17 statistical software. Results indicated significant spatial variations in conductivity, organic matter content and Cr concentrations among organic and non-organic study sites. The Cr, Cd and Pb concentrations recorded from roots and leaves of Centella asiatica were higher than the safe limits for consumption established by the European Union. The health risk analysis indicated that there is a potential of hyper-accumulating Cd in the roots of Centella asiatica. Further, the THQ and HI of the heavy metals indicated possible adverse non-cancer health risks associated with long-term consumption of leaves of Centella asiatica. Therefore, necessary precautionary actions to prevent the excessive buildup of Cr, Cd and Pb in the edible portions of Centella asiatica are essential in order to ensure consumer safety.

scholarly journals Left Atrial Diameter and Albumin with Renal Outcomes in Chronic Kidney Disease

2013 ◽  
Vol 10 (5) ◽  
pp. 575-584 ◽  
Author(s):  
Szu-Chia Chen ◽  
Jer-Ming Chang ◽  
Yi-Chun Tsai ◽  
Jiun-Chi Huang ◽  
Ho-Ming Su ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Left Atrial ◽  
Left Atrial Diameter ◽  
Renal Outcomes
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