Albuminuria and reduced glomerular filtration rate for predicting the renal outcomes in type 2 diabetic patients

Nephrology ◽  
2015 ◽  
Vol 20 (8) ◽  
pp. 531-538 ◽  
Author(s):  
Nobue Tanaka ◽  
Tetsuya Babazono ◽  
Michino Takagi ◽  
Naoshi Yoshida ◽  
Kiwako Toya ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Renal Outcomes ◽  
Type 2 Diabetic

scholarly journals Modified Glomerular Filtration Rate-Estimating Equations Developed in Asiatic Population for Chinese Patients with Type 2 Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Xun Liu ◽  
Xilian Qiu ◽  
Chenggang Shi ◽  
Hui Huang ◽  
Jianhua Huang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Chinese Patients ◽  
Absolute Difference ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Objectives. To evaluate eight modified equations developed in Asiatic populations in type 2 diabetic patients in China.Methods. A total of 209 Chinese patients with type 2 diabetes were recruited. Using the technetium—99m diethylenetriaminepentaacetic acid—glomerular filtration rate (GFR) to act as the reference, comparisons of their efficiency to estimate GFR in the subjects were made between various equations.Results. Median of difference of the Chinese equation 1 was the lowest (median of difference, 0.51 mL/min/1.73 m2). Median percent of absolute difference of the Chinese equation 2 was less than those of the other equations (26.97 versus ranged from 32.54 to 37.61 mL/min/1.73 m2, [P<0.001for all]). Precision of the simplified reexpressed MDRD equation was the best (92.9 mL/min/1.73 m2). Accuracies of the Chinese equation 2 were greater (P<0.05for all). There was also an improvement in chronic kidney disease (CKD) stage misclassification of the Chinese equation 2 (55.0 versus ranged from 61.2 to 64.6%, [P<0.001for all]). However, the 30% accuracies of all the equations were less than 70%.Conclusions. Our study highlighted a limitation in the use of the above equations in the majority of Chinese diabetic subjects. A better equation is needed in order to give an accurate estimation of GFR in type 2 diabetic patients in China.

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