Chronic renal failure of unknown origin is caused byHNF1Bmutations in 9% of adult patients: A single centre cohort analysis

Nephrology ◽  
2014 ◽  
Vol 19 (4) ◽  
pp. 202-209 ◽  
Author(s):  
Claudio Musetti ◽  
Marco Quaglia ◽  
Simona Mellone ◽  
Alessia Pagani ◽  
Ileana Fusco ◽  
...  
2018 ◽  
Vol 70 (1) ◽  
pp. 88-91
Author(s):  
Mohammed Dhafer Yahya Alzamanan ◽  
Abdullah Salem Mohammed Al Rayshan ◽  
Abdullah Saleh Alyami

Author(s):  
Rachael O. Aliu ◽  
Elizabeth A. Awoyesuku ◽  
Chinyere N. Pedro-Egbe

Aims: To determine the demographics and pattern of ocular diseases in patients with Chronic Kidney Disease at the University of Port Harcourt Teaching Hospital. Study Design: This was a hospital-based cross-sectional study. Place and Duration of Study: This study was carried out at the Dialysis clinic of the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria from February 2013 to February 2014. Methodology: The Sample size was estimated to be 85 adult patients and cconsecutive adult patients with chronic renal failure who are having haemodialysis were enrolled into the study. The patients who met the inclusion criteria were randomly booked at the Dialysis Clinic and had no prior knowledge of the study; hence there was no bias in case selection. Ethical approval was obtained from the institutions ethical committee. Each participant had a comprehensive ocular examination including fundus photography. Subjects needing further evaluation and treatment were referred to the Eye Clinic of the Ophthalmology Department of the University of Port Harcourt Teaching Hospital, Port Harcourt. Results: A total of 170 eyes of 85 persons were examined in this study (100% coverage). A total of 30 (35.4%) females and 55 (64.6%) males were examined giving a male to female ratio of 1.8:1. Approximately half of the study subjects (54.1%) had no previous eye problem prior to developing chronic renal failure while about a quarter (n= 20, 23.5%) had refractive error and difficulty in reading near prints .After diagnosis of chronic kidney disease however a total of 40 (47%) of study subjects had visual impairment while 2(2.4%) were blind and 43(50.6%) of the study population however had normal vision. Conclusion: Chronic Kidney disease is an important cause of ocular morbidity in our environment with majority of those affected being males in the third to fifth decades of life. Posterior segment disorders were the commonest disorders seen.


2021 ◽  
Vol 10 (7) ◽  
pp. 1380
Author(s):  
Jerome Razanamahery ◽  
Bastien Bouldoires ◽  
Sebastien Humbert ◽  
Philip Bielefeld ◽  
Veronique Fournier ◽  
...  

Objectives: To compare adult patients’ characteristics suffering from idiopathic retroperitoneal fibrosis between “relapse-free” and relapsing patients at the diagnosis and identify factors associated with relapse at initial presentation. Methods: We conducted a retrospective multicentric study in four hospitals in Eastern France, from 1993 to 2020, of adult patients suffering from idiopathic retroperitoneal fibrosis. We analyzed clinical, biological, and radiological features at diagnosis and during a forty-month follow-up. Results: Of 47 patients suffering from retroperitoneal fibrosis, 21 patients had idiopathic retroperitoneal fibrosis. Among them, 13 experienced one or more relapses during follow-up. At diagnosis, clinical characteristics, relevant comorbidities, biological and radiological features were similar between groups. Smoking cessation seems associated with decreased relapse risk (p: 0.0624). A total of 8 patients developed chronic renal failure during follow-up. Ureteral infiltration at diagnosis was associated with evolution to chronic renal failure (p: 0.0091). Conclusion: No clinical, biological, or radiological features could predict relapse at retroperitoneal fibrosis diagnosis, but smoking cessation may prevent relapse.


2011 ◽  
Vol 106 ◽  
pp. S41
Author(s):  
Muhammad Umar ◽  
Zubia Jamil ◽  
Imtiaz Qureshi ◽  
Ali Usman ◽  
Hamama Bushra ◽  
...  

2011 ◽  
Vol 106 ◽  
pp. S41
Author(s):  
Muhammad Umar ◽  
Zubia Jamil ◽  
Muhammad Baloch ◽  
Hamama Bushra ◽  
Imtiaz Qureshi ◽  
...  

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