Tonsillectomy ameliorates histological damage of recurrent immunoglobulin A nephropathy after kidney transplantation

Nephrology ◽  
2013 ◽  
Vol 18 (12) ◽  
pp. 808-812 ◽  
Author(s):  
Kiyohiko Hotta ◽  
Yuichiro Fukasawa ◽  
Mayuko Akimoto ◽  
Tatsu Tanabe ◽  
Hajime Sasaki ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Immunoglobulin A ◽  
Immunoglobulin A Nephropathy ◽  
Histological Damage

scholarly journals Sodium Sensitivity of Blood Pressure Appearing Before Hypertension and Related to Histological Damage in Immunoglobulin A Nephropathy

Hypertension ◽  
2001 ◽  
Vol 38 (1) ◽  
pp. 81-85 ◽  
Author(s):  
Yoshio Konishi ◽  
Noriyuki Okada ◽  
Mikio Okamura ◽  
Takashi Morikawa ◽  
Michiaki Okumura ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Immunoglobulin A ◽  
Immunoglobulin A Nephropathy ◽  
Sodium Sensitivity ◽  
Histological Damage

scholarly journals Efficacy of tonsillectomy for the treatment of immunoglobulin A nephropathy recurrence after kidney transplantation

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Hiroshi Nihei ◽  
Ken Sakai ◽  
Seiichiro Shishido ◽  
Kazutoshi Sibuya ◽  
Hideo Edamatsu ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Immunoglobulin A ◽  
Immunoglobulin A Nephropathy

scholarly journals Recurrence of immunoglobulin A nephropathy after kidney transplantation: a narrative review of the incidence, risk factors, pathophysiology and management of immunosuppressive therapy

2020 ◽  
Vol 13 (5) ◽  
pp. 758-767
Author(s):  
Barbara Infante ◽  
Michele Rossini ◽  
Adelaide Di Lorenzo ◽  
Nicola Coviello ◽  
Castellano Giuseppe ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Renal Disease ◽  
Immunosuppressive Treatment ◽  
Graft Loss ◽  
Immunoglobulin A ◽  
Supportive Therapy ◽  
Kidney Graft ◽  
Immunoglobulin A Nephropathy ◽  
Kidney Transplant Recipients ◽  
End Stage

Abstract Glomerulonephritis (GN) is the underlying cause of end-stage renal failure in 30–50% of kidney transplant recipients. It represents the primary cause of end-stage renal disease for 25% of the dialysis population and 45% of the transplant population. For patients with GN requiring renal replacement therapy, kidney transplantation is associated with superior outcomes compared with dialysis. Recurrent GN was previously considered to be a minor contributor to graft loss, but with the prolongation of graft survival, the effect of recurrent disease on graft outcome assumes increasing importance. Thus the extent of recurrence of original kidney disease after kidney transplantation has been underestimated for several reasons. This review aims to provide updated knowledge on one particular recurrent renal disease after kidney transplantation, immunoglobulin A nephropathy (IgAN). IgAN is one of the most common GNs worldwide. The pathogenesis of IgAN is complex and remains incompletely understood. Evidence to date is most supportive of a several hit hypothesis. Biopsy is mandatory not only to diagnose the disease in the native kidney, but also to identify and characterize graft recurrence of IgAN in the kidney graft. The optimal therapy for IgAN recurrence in the renal graft is unknown. Supportive therapy aiming to reduce proteinuria and control hypertension is the mainstream, with corticosteroids and immunosuppressive treatment tailored for certain subgroups of patients experiencing a rapidly progressive course of the disease with active lesions on renal biopsy and considering safety issues related to infectious complications.

scholarly journals Five cases of tonsillectomy and steroid pulse therapy for recurrent immunoglobulin A nephropathy after kidney transplantation

2013 ◽  
Vol 3 (1) ◽  
pp. 118-122 ◽  
Author(s):  
Yoshie Hoshino ◽  
Yasutomo Abe ◽  
Mariko Endo ◽  
Sachiko Wakai ◽  
Hiroki Shirakawa ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Immunoglobulin A ◽  
Pulse Therapy ◽  
Steroid Pulse Therapy ◽  
Immunoglobulin A Nephropathy ◽  
Steroid Pulse
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