A case of Marfan syndrome with ischemic stroke due to middle cerebral artery dissection

2018 ◽  
Vol 6 (6) ◽  
pp. 194-196
Author(s):  
Tadashi Ozawa ◽  
Akihiro Toyohara ◽  
Younhee Kim ◽  
Takafumi Mashiko ◽  
Reiji Koide ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Marfan Syndrome ◽  
Cerebral Artery ◽  
Artery Dissection ◽  
Cerebral Artery Dissection

scholarly journals A case of middle cerebral artery dissection onset of ischemic stroke successfully diagnosed by MRA source images

Nosotchu ◽  
2014 ◽  
Vol 36 (5) ◽  
pp. 366-369
Author(s):  
Mitsuteru Shimohata ◽  
Keiko Kitazawa ◽  
Yasushi Ito ◽  
Yumiko Watanabe ◽  
Hajime Tanaka
Keyword(s):  
Ischemic Stroke ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Dissection ◽  
Cerebral Artery Dissection

scholarly journals Spontaneous Middle Cerebral Artery Dissection Demonstrated by High-Resolution T1-Weighted 3D Image

2013 ◽  
Vol 36 (3) ◽  
pp. 243-244 ◽  
Author(s):  
Masahiro Uemura ◽  
Yasuhisa Akaiwa ◽  
Masafumi Toriyabe ◽  
Takuya Mashima ◽  
Kenshi Terajima ◽  
...  
Keyword(s):  
High Resolution ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Dissection ◽  
3D Image ◽  
Cerebral Artery Dissection

The value of plasma fibrillin-1 level in patients with spontaneous cerebral artery dissection

Neurology ◽  
2018 ◽  
Vol 90 (9) ◽  
pp. e732-e737 ◽  
Author(s):  
Zhu Zhu ◽  
Weijun Tang ◽  
Liang Ge ◽  
Xiang Han ◽  
Qiang Dong
Keyword(s):  
Ischemic Stroke ◽  
Cerebral Artery ◽  
Acute Stage ◽  
Artery Dissection ◽  
Class Iii ◽  
Severity Grading ◽  
Fibrillin 1 ◽  
Stroke Group ◽  
Healthy Participants ◽  
Cerebral Artery Dissection

ObjectiveTo explore the value of plasma fibrillin-1 levels in patients with spontaneous cerebral artery dissection (sCeAD).MethodsA single-center prospective cohort of 99 consecutive patients with sCeAD between February 2013 and December 2015 were age and sex matched with 115 patients with non-sCeAD ischemic stroke and 20 healthy participants undergoing routine physical examination. The plasma fibrillin-1 level was measured with ELISA and compared among the 3 groups. The associations of fibrillin-1 with site, acuity, and severity of dissection, as well as clinical and radiographic prognosis of patients, were analyzed.ResultsOne hundred nine plasma samples from 99 patients with sCeAD, 115 from disease control patients, and 20 from healthy participants were collected. The plasma fibrillin-1 level of the dissection group (mean 85.56 ng/mL [95% confidence interval 81.53–89.59]) was higher than that of non-sCeAD ischemic stroke group (77.13 ng/mL [73.64–80.63], p = 0.015) or healthy controls (73.04 ng/mL [65.94–80.13], p = 0.029). Such differences were most prominent in the acute stage (97.64 ng/mL [91.64–103.64], 74.39 ng/mL [68.95–79.84], and 73.04 ng/mL [65.95–80.13], respectively). A cutoff value of 88.455 ng/mL was determined to differentiate acute dissection from nondissection stroke with a sensitivity of 0.778 and a specificity of 0.800. Higher fibrillin-1 level was detected in patients with more severe dissection radiographically (p < 0.001), while patients with lower fibrillin-1 concentration at baseline achieved better morphologic recovery on follow-up imaging tests (p = 0.003).ConclusionPlasma fibrillin-1 is a promising biomarker for aiding the diagnosis of acute sCeAD and may have potential value in lesion severity grading and radiographic prognosis prediction.Classification of evidenceThis study provides Class III evidence that patients with sCeAD have significantly higher levels of plasma fibrillin-1 than patients with ischemic stroke attributable to a cause other than sCeAD.

Successful Intra-arterial Stent Thrombectomy in Acute Infarction Caused by Spontaneous Middle Cerebral Artery Dissection

2016 ◽  
Vol 34 (3) ◽  
pp. 231-234
Author(s):  
Younggun Lee ◽  
JoonNyung Heo ◽  
Min Cheol Park ◽  
Sungwoo Kang ◽  
So Hoon Yoon ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Dissection ◽  
Acute Infarction ◽  
Cerebral Artery Dissection

Abstract TMP106: Early Elevation of D-dimer Values Is Associated With Neurological Deterioration in Acute Ischemic Stroke due to Cerebral Artery Dissection

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Kazuki Fukuma ◽  
Masafumi Ihara ◽  
Hiroshi Yamagami ◽  
Masatoshi Koga ◽  
Kazunori Toyoda ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Aortic Dissection ◽  
Acute Ischemic Stroke ◽  
Anticoagulant Therapy ◽  
Cerebral Artery ◽  
Neurological Deterioration ◽  
Artery Dissection ◽  
Cerebral Artery Dissection ◽  
D Dimer ◽  
Early Elevation

Background and Purpose: Plasma D-dimer is a complementary diagnostic marker in patients with acute aortic dissection. However, it remains unknown whether monitoring of D-dimer is of diagnostic value for in-hospital management of cerebral artery dissection. The aim of this study was to identify the relationship between D-dimer and neurological deterioration in acute ischemic stroke due to cerebral artery dissection. Methods: We retrospectively studied 90 consecutive patients (60 men; mean age, 51.0 years) with ischemic stroke due to cerebral or cervical artery dissection who were admitted to our hospital within three weeks after the onset between Jan 2005 and May 2015. Plasma D-dimer values were measured at least on admission and within a week. Neurological deterioration (ND) was defined as an increase of ≥ 3 points in the National Institutes of Health Stroke Scale (NIHSS) score within 3 weeks after admission. D-dimer ratio (DDR, peak D-dimer between the 2nd and 7th hospital day / on admission) was measured as an index of D-dimer elevation at an early phase. Associations between ND and patient characteristics including D-dimer values and acute treatment regimen were examined. Results: Eight of the 90 patients (8.9%) presented ND, accompanied by progression of stenosis in cerebral artery dissection. None of them had aortic dissection, severe heart failure and active malignant tumor. Fifty-nine of the 90 patients (65.6%) received anticoagulant therapy, 33 (36.7%) antiplatelet therapy and 5 (5.6%) thrombolysis in the acute phase. The mean D-dimer value was 2.80±1.81 (standard deviation, SD) at the time of progression. In univariate analysis, DDR was higher in ND group (3.93±2.45 SD) than non-ND group (1.46±1.04 SD) (p<0.01), whereas the D-dimer value on admission was similar in 2 groups . Multivariate logistic regression analysis showed DDR was related to ND before [OR: 1.57; 95% CI: 1.15-2.38, p<0.01] and after controlling for thrombolysis, anticoagulant therapy and deep vein thrombosis [OR: 1.63; 95% CI: 1.14-2.62, p<0.01]. Conclusion: Early elevation of D-dimer values may predict neurological deterioration with progression of stenosis in acute ischemic stroke due to cerebral artery dissection

Middle Cerebral Artery Dissection

1996 ◽  
Vol 27 (06) ◽  
pp. 331-332 ◽  
Author(s):  
C. Adams ◽  
C. Trevenen
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Artery Dissection ◽  
Cerebral Artery Dissection
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