scholarly journals Concurrent tau pathologies in frontotemporal lobar degeneration with TDP‐43 pathology

2021 ◽  
Author(s):  
Shunsuke Koga ◽  
Xiaolai Zhou ◽  
Aya Murakami ◽  
Cristhoper Fernandez De Castro ◽  
Matthew C. Baker ◽  
...  
Keyword(s):  
Frontotemporal Lobar Degeneration

Frontotemporal Lobar Degeneration: Characterizing Semantic Binding and Abstracted Meaning Abilities

2009 ◽  
Vol 19 (4) ◽  
pp. 117-125 ◽  
Author(s):  
Raksha Anand ◽  
John Hart ◽  
Patricia S. Moore ◽  
Sandra B. Chapman
Keyword(s):  
Frontotemporal Lobar Degeneration ◽  
Assessment Tools ◽  
Progressive Decline ◽  
Cognitively Normal ◽  
Nonfluent Aphasia ◽  
Traditional Assessment ◽  
Language Measures ◽  
Semantic Object ◽  
Semantic Problem ◽  
Progressive Nonfluent Aphasia

Abstract Purpose: Frontotemporal lobar degeneration (FTLD) encompasses a group of neurodegenerative disorders characterized by gradual and progressive decline in behavior and/or language. Identifying the subtypes of FTLD can be challenging with traditional assessment tools. Growing empirical evidence suggests that language measures might be useful in differentiating FTLD subtypes. Method: In this paper, we examined the performance of five individuals with FTLD (two with frontotemporal dementia, two with semantic dementia, and one with progressive nonfluent aphasia) and 10 cognitively normal older adults on measures of semantic binding (Semantic Object Retrieval Test and semantic problem solving) and abstracted meaning (generation of interpretive statement and proverb interpretation). Results and Conclusion: A differential profile of impairment was observed in the three FTLD subtypes on these four measures. Further examination of these measures in larger groups will establish their clinical utility in differentiating the FTLD subtypes.

hnRNPA2B1 and hnRNPA1 mutations are rare in patients with “multisystem proteinopathy” and frontotemporal lobar degeneration phenotypes

2014 ◽  
Vol 35 (4) ◽  
pp. 934.e5-934.e6 ◽  
Author(s):  
Isabelle Le Ber ◽  
Inge Van Bortel ◽  
Gael Nicolas ◽  
Kawtar Bouya-Ahmed ◽  
Agnès Camuzat ◽  
...  
Keyword(s):  
Frontotemporal Lobar Degeneration

A male case of frontotemporal lobar degeneration with behavioural and psychiatric symptoms responding to a low dose of escitalopram

2021 ◽  
Author(s):  
Atsuko Ikenouchi ◽  
Issei Seki ◽  
Kei Takaoka ◽  
Naomichi Okamoto ◽  
Sayuri Murakami ◽  
...  
Keyword(s):  
Frontotemporal Lobar Degeneration ◽  
Low Dose ◽  
Psychiatric Symptoms
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