Interfering with lysophosphatidic acid receptor edg2/lpa 1 signalling slows down disease progression in SOD1‐G93A transgenic mice

2021 ◽  
Author(s):  
Ángela Gento‐Caro ◽  
Esther Vilches‐Herrando ◽  
Victoria García‐Morales ◽  
Federico Portillo ◽  
Guillermo Rodríguez‐Bey ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Disease Progression ◽  
Lysophosphatidic Acid ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
G93a Transgenic Mice

scholarly journals Differential expression of LPAR3 in cancer of the vulva.

2021 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Disease Progression ◽  
Differential Expression ◽  
Lysophosphatidic Acid ◽  
Microarray Data ◽  
Transcriptome Analysis ◽  
Vulvar Cancer ◽  
Vulvar Carcinoma ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Tissue Of Origin

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of lysophosphatidic acid receptor 3, encoded by LPAR3, in cancer of the vulva. LPAR3 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).

The status of the lysophosphatidic acid receptor type 1 (LPA1R)

MedChemComm ◽  
2015 ◽  
Vol 6 (1) ◽  
pp. 13-23 ◽  
Author(s):  
Inés González-Gil ◽  
Debora Zian ◽  
Henar Vázquez-Villa ◽  
Silvia Ortega-Gutiérrez ◽  
María L. López-Rodríguez
Keyword(s):  
Drug Development ◽  
Lysophosphatidic Acid ◽  
Receptor Type ◽  
Current Status ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
The Status ◽  
Development Pipeline

The current status of the LPA1receptor and its ligands in the drug development pipeline is reviewed.

scholarly journals Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus

2008 ◽  
Vol 39 (3) ◽  
pp. 342-355 ◽  
Author(s):  
Elisa Matas-Rico ◽  
Beatriz García-Diaz ◽  
Pedro Llebrez-Zayas ◽  
Diana López-Barroso ◽  
Luis Santín ◽  
...  
Keyword(s):  
Dentate Gyrus ◽  
Lysophosphatidic Acid ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor
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