Inflammation and oxidative stress in corneal tissue in experimental keratitis due to Fusarium solani : Amelioration following topical therapy with voriconazole and epigallocatechin gallate

Mycoses ◽  
2017 ◽  
Vol 61 (3) ◽  
pp. 159-171 ◽  
Author(s):  
Vasanthakumar V. Ruban ◽  
Philip T. Archana ◽  
Mahalingam Sundararajan ◽  
Pitchairaj Geraldine ◽  
Philip A. Thomas
Keyword(s):  
Oxidative Stress ◽  
Fusarium Solani ◽  
Topical Therapy ◽  
Epigallocatechin Gallate ◽  
Corneal Tissue ◽  
And Oxidative Stress ◽  
Experimental Keratitis

scholarly journals (+)-Catechin and (-)-epigallocatechin gallate: are these promising antioxidant therapies for frozen goat semen?

2019 ◽  
Vol 71 (2) ◽  
pp. 521-528 ◽  
Author(s):  
E.C.B. Silva ◽  
L.C.P. Arruda ◽  
J.I.T. Vieira ◽  
P.C. Soares ◽  
M.M.P. Guerra
Keyword(s):  
Oxidative Stress ◽  
Plasma Membrane ◽  
Epigallocatechin Gallate ◽  
Progressive Motility ◽  
Acrosome Integrity ◽  
And Oxidative Stress

ABSTRACT The aim of this study was to evaluate the effects of different concentrations of (+)-catechin or (-)-epigallocatechin gallate (EGCG) on goat semen freezability. Poolsof semen were processed (Experiment 1: 0, 15, 25, 50, 75, or 100µM (+)-catechin; Experiment 2: 0, 15, 25, 50, 75, or 100µM EGCG) and frozen. After thawing, the samples were evaluated for kinematics, plasma membrane (PMi) and acrosome integrity, morphology, and oxidative stress, at 0 and 1h. In Experiment 1, at 0h, VSL and VAP were greater (P<0.05) with 15µM than with 50 and 100; WOB was lower (P<0.05) with 100µM than with 0, 15, and 25; and BCF was higher (P<0.05) with 75 and 100µM than with 0. In turn, in Experiment 2, progressive motility was higher (P<0.05) with0 and 15µM than with50 and 75; LIN was lower (P<0.05) with75 and100µM than with0 and 15; WOB was higher (P<0.05) with0 and 15µM; and PMi was greater (P<0.05) with100µM than 0. Thus, (+)-catechin or EGCG at higher concentrations inhibits the kinematics of frozen goat sperm, in a transitory way, and 100µM of EGCG preserves the PMi.

Oxidative stress in corneal tissue in experimental keratitis due to Aspergillus flavus: Effect of topical voriconazole therapy

2019 ◽  
Vol 21 ◽  
pp. 101323
Author(s):  
Vasanthakumar Vasantha Ruban ◽  
Muniyandi Anbukkarasi ◽  
Thiraviyam Anand ◽  
Philip A. Thomas ◽  
Pitchairaj Geraldine
Keyword(s):  
Oxidative Stress ◽  
Aspergillus Flavus ◽  
Corneal Tissue ◽  
Experimental Keratitis

Impact of exercise and/or beta‐alanine and epigallocatechin gallate on muscle function and oxidative stress in aged mice (1027.2)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Brandt Pence ◽  
Trisha Gibbons ◽  
Tushar Bhattacharya ◽  
Houston Mach ◽  
Jessica Ossyra ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Muscle Function ◽  
Epigallocatechin Gallate ◽  
Aged Mice ◽  
Beta Alanine ◽  
And Oxidative Stress

Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis

2020 ◽  
pp. 1-8
Author(s):  
Hasan Haci Yeter ◽  
Berfu Korucu ◽  
Elif Burcu Bali ◽  
Ulver Derici
Keyword(s):  
Oxidative Stress ◽  
Vitamin D ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Vitamin D Analog ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

Abstract. Background: The pathophysiological basis of chronic kidney disease and its complications, including cardiovascular disease, are associated with chronic inflammation and oxidative stress. We investigated the effects of active vitamin D (calcitriol) and synthetic vitamin D analog (paricalcitol) on oxidative stress in hemodialysis patients. Methods: This cross-sectional study was composed of 83 patients with a minimum hemodialysis vintage of one year. Patients with a history of any infection, malignancy, and chronic inflammatory disease were excluded. Oxidative markers (total oxidant and antioxidant status) and inflammation markers (C-reactive protein and interleukin-6) were analyzed. Results: A total of 47% (39/83) patients were using active or analog vitamin D. Total antioxidant status was significantly higher in patients with using active or analog vitamin D than those who did not use (p = 0.006). Whereas, total oxidant status and oxidative stress index were significantly higher in patients with not using vitamin D when compared with the patients who were using vitamin D preparation (p = 0.005 and p = 0.004, respectively). On the other hand, total antioxidant status, total oxidant status, and oxidative stress index were similar between patients who used active vitamin D or vitamin D analog (p = 0.6; p = 0.4 and p = 0.7, respectively). Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease.

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