Isolation of Rhodotorula mucilaginosa from blood cultures in a tertiary care hospital

Mycoses ◽  
2017 ◽  
Vol 61 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Iker Falces-Romero ◽  
Emilio Cendejas-Bueno ◽  
María Pilar Romero-Gómez ◽  
Julio García-Rodríguez
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Cultures ◽  
Care Hospital ◽  
Rhodotorula Mucilaginosa

Isolation of Candida in the blood cultures of patients admitted to the Emergency Room in a tertiary care hospital

2019 ◽  
Vol 36 (3) ◽  
pp. 142-146
Author(s):  
Iker Falces-Romero ◽  
María Pilar Romero-Gómez ◽  
Julio García-Rodríguez ◽  
Emilio Cendejas-Bueno
Keyword(s):  
Emergency Room ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Cultures ◽  
Care Hospital

scholarly journals Assessment of clinical profile, antibiotic sensitivity and prescription pattern in blood culture positive enteric fever among pediatric and adult patients admitted in a tertiary care hospital: a prospective study

2019 ◽  
Vol 7 (9) ◽  
pp. 3270
Author(s):  
Swapnil Gautam ◽  
Suraj Purushothaman ◽  
Kinjal P. Patel ◽  
Ajay P. Sankhe ◽  
Madhuri R. Mahadik
Keyword(s):  
Blood Culture ◽  
Prospective Study ◽  
Enteric Fever ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Multidrug Resistant ◽  
Blood Cultures ◽  
Care Hospital ◽  
Prescription Pattern

Background: Asterion Introduction: Enteric fever is a major concern in developing country. It is predominantly caused by serovars typhi and paratyphi of Salmonella enterica. Recently, an upsurge in antimicrobial resistant strains has worsened the management of enteric fever. So, aim of present study is to evaluate the clinical profile, antibiotic sensitivity and prescription pattern in blood culture proven cases of enteric fever in pediatric and adult patients.Methods: Single centre, prospective study was conducted at a tertiary care hospital. Demographic and clinical details of blood culture proven enteric fever admitted in hospital were collected over the period from August 2016 to November 2018.Results: Total 58 blood cultures grew Salmonella spp. , amongst them 84.48 % had growth of Salmonella typhi. Blood culture was sent after a mean period of 9 days and 10 days of fever in pediatric and adult patients respectively. All isolates of S. paratyphi A were pansusceptible, whereas 36.73 % isolates of S. typhi were multidrug resistant and nalidixic acid resistant. 68.97% patients received antibiotics before admission. The difference between mean time to defervescence in patients who received ceftriaxone and those who received more than one antibiotic was not statistically significant. (P value 0.87)Conclusion: Blood cultures are the important diagnostic tool to identify multidrug resistant Salmonellae. Study showed that combination therapy was not statistically superior and awareness of local antimicrobial susceptibility pattern significantly helps for better management of the patients.

scholarly journals Molecular Characterization of Staphylococcus aureus Obtained from Blood Cultures of Paediatric Patients Treated in a Tertiary Care Hospital in Mexico

2021 ◽  
Vol Volume 14 ◽  
pp. 1545-1556
Author(s):  
Guillermo Jose Vazquez-Rosas ◽  
Jocelin Merida-Vieyra ◽  
Gerardo Aparicio-Ozores ◽  
Antonino Lara-Hernandez ◽  
Agustin De Colsa ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Characterization ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Cultures ◽  
Care Hospital ◽  
Paediatric Patients

scholarly journals Prevalence of Plasmid-Mediated Quinolone Resistance Genes among Ciprofloxacin-NonsusceptibleEscherichia coliandKlebsiella pneumoniaeIsolated from Blood Cultures in Korea

2014 ◽  
Vol 25 (3) ◽  
pp. 163-169 ◽  
Author(s):  
Hee Young Yang ◽  
You Sun Nam ◽  
Hee Joo Lee
Keyword(s):  
Tertiary Care Hospital ◽  
Direct Sequencing ◽  
Tertiary Care ◽  
Hospital Setting ◽  
Antibiotic Use ◽  
Blood Cultures ◽  
Quinolone Resistance ◽  
Care Hospital ◽  
E Coli ◽  
Polymerase Chain

OBJECTIVES:To analyze the prevalence of plasmid-mediated quinolone resistance (PMQR) determinants in ciprofloxacin-nonsusceptibleEscherichia coliandKlebsiella pneumoniaeisolated from patients at a tertiary care hospital in Korea.METHODS: A total of 102 nonduplicate isolates of ciprofloxacin-intermediate or ciprofloxacin-resistantE coli(n=80) andK pneumoniae(n=22) from blood cultures were obtained. Theqnr(qnrA, qnrB,qnrS),aac(6′)-Ib-cr,qepAandoqxABgenes were detected using polymerase chain reaction (PCR) and confirmed using direct sequencing. To determine whether the PMQR-positive plasmid was horizontally transferable, conjugation experiments were performed.RESULTS: Of the 102 isolates, 81 (79.4%) had one or more PMQR genes; these consisted of 59 (73.8%)E coliand 22 (100%)K pneumoniaeisolates. Theqnrgenes were present in 15 isolates (14.7%):qnrB4was detected in 10.8% andqnrS1was detected in 3.9%. Theaac(6′)-Ib-cr,qepAandoqxABgenes were detected in 77.5%, 3.9% and 10.8%, respectively. In conjugation experiments, PMQR genes were successfully transferred from seven (8.6%) isolates. The range of minimum inhibitory concentrations of ciprofloxacin for these seven transconjugants increased to 0.5 mg/L to 1 mg/L, which was 16- to 33-fold that of the recipientE coliJ53 bacteria.CONCLUSIONS: PMQR genes were highly prevalent among ciprofloxacin-nonsusceptibleE coliandK pneumoniaefrom blood cultures in the authors’ hospital. Therefore, it is necessary to monitor for the spread of PMQR genes of clinical isolates and to ensure careful antibiotic use in a hospital setting.

scholarly journals Study of prevalence and antimicrobial susceptibility pattern of blood culture isolates from a tertiary care hospital of North India

2018 ◽  
Vol 6 (12) ◽  
pp. 4046 ◽  
Author(s):  
Asifa Nazir ◽  
Ifshana Sana ◽  
Bushra Yousuf Peerzada ◽  
Tabindah Farooq
Keyword(s):  
Blood Culture ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Bloodstream Infections ◽  
Blood Cultures ◽  
Care Hospital ◽  
Bacterial Isolates ◽  
Gram Positive ◽  
Gram Negative ◽  
Culture Positive

Background: Bacterial bloodstream infections (BSIs) are important causes of morbidity and mortality world-wide. The choice of antimicrobial therapy for bloodstream infections is often empirical and based on the knowledge of local antimicrobial activity profiles of the most common bacteria causing such infections. The objective of the study was to determine the pattern of bacterial isolates from the blood cultures in a teaching hospital and determine their antibiotic resistance and provide guidelines for choosing an effective antibiotic therapy in cases of septicaemia.Methods: The etiological and antimicrobial susceptibility profile of blood cultures over a period of one year at a tertiary care hospital was studied. Blood culture positive isolates were identified by BacT/Alert3D, an automated blood culture system, while as identification of the isolates from these samples and their antimicrobial sensitivity testing was performed with Vitek2 Compact.Results: There were 2231 blood culture samples, of which 565 (25.3%) were identified to be culture positive. Out of 565 positive cultures, 447 (79.1%) showed bacterial growth; Gram positive were 306 (54.2%) and Gram negative were 141 (24.9%). Candida species were isolated from 118 (20.9%) of positive samples. The most frequently identified Gram-positive bacteria were Coagulase-negative staphylococci 208 (67.9%) and the most common Gram-negative isolates were Acinetobacter species 89 (63.1%). The most sensitive drugs for gram-positive isolates were vancomycin, and linezolid while as gram-negative isolates showed 100% sensitivity to colistin and tigecycline.Conclusions: This study reveals a significant prevalence of bacterial isolates in blood and it highlights the need for periodic surveillance of etiologic agent and antibiotic susceptibility to prevent further emergence and spread of resistant bacterial pathogens.

scholarly journals Prevalence of Candidemia with Susceptibility Pattern in a Tertiary Care Hospital in North India

2021 ◽  
Vol 8 (16) ◽  
pp. 1041-1046
Author(s):  
Ashish William ◽  
Aroma Oberoi ◽  
Divya Dsouza ◽  
Arpit Oberoi
Keyword(s):  
Candida Albicans ◽  
Candida Species ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Stream ◽  
Blood Cultures ◽  
North India ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Candida Infections

BACKGROUND Blood stream infections (BSI) caused by various candida species have been reported from many countries worldwide and are a significant cause of morbidity and mortality in hospitalised patients. The alarming increase in infections with multidrug resistant bacteria is due to overuse of broad-spectrum antimicrobials, which leads to over growth of candida species; thus, enhancing its opportunity to cause the disease. During recent decades, there has been a change in the epidemiology of candida infections, characterised by a progressive shift from a predominance of Candida albicans to non-albicans candida species. This study was conducted to determine the prevalence of candidemia in blood stream and the susceptibility pattern in a tertiary care hospital in North India. METHODS This is retrospective study which has been conducted for a period of 1.5 years form April 2015 to October 2016. All blood cultures received during this period by BACTEC automated culture system and Becton Dickinson were included in the study. The culture was done on positive blood culture bottles and were cultured on Sabouraud dextrose agar. Recovered candida isolates were speciated and antifungal susceptibility testing was performed as per Clinical and Laboratory Standards Institute guidelines (CLSI). RESULTS A total of 80 out of 8020 blood cultures were culture positive for candida species. Therefore, the overall prevalence rate of isolation of candida species was 0.99 % in our study. The incidence of blood stream infection caused by non albicans candida species (73.8 %) was higher than Candida albicans (26.2 %). Among NAC species, Candida tropicalis (44 %) was the most common, followed by Candida parapsilosis (24 %), Candida glabrata (17 %), Candida krusei (8.5 %), Candida guilliermondii (5 %) and Candida dubliniensis (1.5 %). Candidemia was predominantly observed in ICU patients. Resistance was significantly higher among non-albicans candida species (NAC), amphotericin B, fluconazole, ketoconazole, itraconazole and clotrimazole - 96.72 %, 59.84 %, 51.23 %, 19.44 %, and 56.15 % respectively. CONCLUSIONS With an ever-expanding array of non-candida species-related infections in highly compromised and terminally ill patients, understanding the activity of the antifungal agents used against both C. albicans and nonalbicans species becomes mandatory. Continued surveillance of candida infections will be required to document changes in epidemiology and antifungal susceptibilities. KEYWORDS Bloodstream Infections, Candidemia, Non Albicans Candida (NAC)

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