Utility of galactomannan antigen detection in bronchoalveolar lavage fluid in immunocompromised patients

Mycoses ◽  
2013 ◽  
Vol 56 (5) ◽  
pp. 552-558 ◽  
Author(s):  
Kyle R. Brownback ◽  
Lucas R. Pitts ◽  
Steven Q. Simpson
CHEST Journal ◽  
2018 ◽  
Vol 154 (3) ◽  
pp. 722-725 ◽  
Author(s):  
Kristina Affolter ◽  
Desiree M. Schumann ◽  
Michael Tamm ◽  
Kathleen Jahn ◽  
Aline Siebeneichler ◽  
...  

2008 ◽  
Vol 15 (12) ◽  
pp. 1760-1763 ◽  
Author(s):  
S. Husain ◽  
C. J. Clancy ◽  
M. H. Nguyen ◽  
S. Swartzentruber ◽  
H. Leather ◽  
...  

ABSTRACT We have evaluated the Platelia Aspergillus enzyme immunoassay for detection of galactomannan in bronchoalveolar lavage (BAL) specimens in solid organ transplant patients with aspergillosis. The precision and reproducibility in serum or BAL to which galactomannan was added were similar. Sensitivity was 81.8% in patients with aspergillosis, and specificity was 95.8% in lung transplant patients who underwent BAL for surveillance for infection or rejection. Among transplant controls, positive results were more common in patients (i) who underwent diagnostic BAL performed for evaluation of symptoms or chest computed tomographic abnormalities, (ii) who had undergone lung transplantation, or (iii) who were colonized with Aspergillus. Galactomannan testing in BAL is useful for diagnosis of aspergillosis in transplant patients. The significance of positive results in patients without confirmed aspergillosis requires further evaluation.


Thorax ◽  
1994 ◽  
Vol 49 (9) ◽  
pp. 872-874 ◽  
Author(s):  
P Jimenez ◽  
M Meneses ◽  
F Saldias ◽  
M Velasquez

2017 ◽  
Vol 32 (1) ◽  
pp. e13149 ◽  
Author(s):  
Elena Beam ◽  
Jeffrey J. Germer ◽  
Brian Lahr ◽  
Joseph D.C. Yao ◽  
Andrew Harold Limper ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document