scholarly journals Organic acid, a virulence factor for pathogenic fungi, causing postharvest decay in fruits

2021 ◽  
Author(s):  
Wenxiao Jiao ◽  
Xin Liu ◽  
Youyuan Li ◽  
Boqiang Li ◽  
Yamin Du ◽  
...  
Keyword(s):  
Organic Acid ◽  
Virulence Factor ◽  
Pathogenic Fungi ◽  
Postharvest Decay

scholarly journals Potential Role of Phospholipases in Virulence and Fungal Pathogenesis

2000 ◽  
Vol 13 (1) ◽  
pp. 122-143 ◽  
Author(s):  
Mahmoud A. Ghannoum
Keyword(s):  
Virulence Factor ◽  
Cell Damage ◽  
Pathogenic Fungi ◽  
Microbial Pathogens ◽  
Immunogold Electron Microscopy ◽  
Lytic Enzymes ◽  
Fungal Virulence ◽  
Phospholipase B ◽  
Genes Encoding

SUMMARY Microbial pathogens use a number of genetic strategies to invade the host and cause infection. These common themes are found throughout microbial systems. Secretion of enzymes, such as phospholipase, has been proposed as one of these themes that are used by bacteria, parasites, and pathogenic fungi. The role of extracellular phospholipase as a potential virulence factor in pathogenic fungi, including Candida albicans, Cryptococcus neoformans, and Aspergillus, has gained credence recently. In this review, data implicating phospholipase as a virulence factor in C. albicans, Candida glabrata, C. neoformans, and A. fumigatus are presented. A detailed description of the molecular and biochemical approaches used to more definitively delineate the role of phospholipase in the virulence of C. albicans is also covered. These approaches resulted in cloning of three genes encoding candidal phospholipases (caPLP1, caPLB2, and PLD). By using targeted gene disruption, C. albicans null mutants that failed to secrete phospholipase B, encoded by caPLB1, were constructed. When these isogenic strain pairs were tested in two clinically relevant murine models of candidiasis, deletion of caPLB1 was shown to lead to attenuation of candidal virulence. Importantly, immunogold electron microscopy studies showed that C. albicans secretes this enzyme during the infectious process. These data indicate that phospholipase B is essential for candidal virulence. Although the mechanism(s) through which phospholipase modulates fungal virulence is still under investigations, early data suggest that direct host cell damage and lysis are the main mechanisms contributing to fungal virulence. Since the importance of phospholipases in fungal virulence is already known, the next challenge will be to utilize these lytic enzymes as therapeutic and diagnostic targets.

scholarly journals Melanin as a virulence factor of Paracoccidioides brasiliensis and other dimorphic pathogenic fungi: a minireview

2008 ◽  
Vol 165 (4-5) ◽  
pp. 331-339 ◽  
Author(s):  
Carlos P. Taborda ◽  
Marcelo B. da Silva ◽  
Joshua D. Nosanchuk ◽  
Luiz R. Travassos
Keyword(s):  
Virulence Factor ◽  
Paracoccidioides Brasiliensis ◽  
Pathogenic Fungi

Melanin as a virulence factor in pathogenic fungi

Mycoses ◽  
1990 ◽  
Vol 33 (5) ◽  
pp. 215-224 ◽  
Author(s):  
Annemarie Polak
Keyword(s):  
Virulence Factor ◽  
Pathogenic Fungi

A rare progressive neurometabolic disease (L-2-hydroxyglutaric aciduria) diagnosed by urinary organic acid analysis

2006 ◽  
Vol 37 (03) ◽  
Author(s):  
S Vlaho ◽  
S Posselt ◽  
V Boda ◽  
M Baz Bartels ◽  
S Parbel ◽  
...  
Keyword(s):  
Organic Acid ◽  
Urinary Organic Acid ◽  
Organic Acid Analysis ◽  
Urinary Organic Acid Analysis

IDENTIFIKASI JENIS JAMUR PATOGEN UNTUK PENGENDALIAN RAYAP TANAH Coptotermes sp.

PERENNIAL ◽  
2010 ◽  
Vol 6 (1) ◽  
pp. 33
Author(s):  
Astuti Arif ◽  
. Syahidah ◽  
Sitti Nuraeni
Keyword(s):  
Key Words ◽  
Pathogenic Fungi ◽  
Wide Distribution ◽  
Subterranean Termite ◽  
The World ◽  
Identification Of Fungi ◽  
Screening And Identification ◽  
Termite Attack ◽  
Penicillium Brevicompactum ◽  
Aspergillus Sp

Fungi have a great diversity and wide distribution at the world. It can be used as the alternative technology for controlling of subterranean termite attack, particularly genus Coptotermes knowned as the wooden destructive organism, by using entomophatogenic fungi. For the purpose of the study, several isolate sources were taken from some locations. The results show that eight numbers of pathogenic fungi was founded by screening and identification of fungi taken from 19 numbers of isolate sources. The pathogenic fungi were Beauveria sp., Penicillium brevicompactum, P. rubrum, Paecilomyces fulvus, Fusarium verticolloides, Pythium sp., and Aspergillus sp. Key words: Jamur entomopatogen, Coptotermes sp.

SOYBEAN AND FLAX SELECTION METHODS

1970 ◽  
pp. 19-23
Author(s):  
V. М. Lukomets ◽  
S. V. Zelentsov
Keyword(s):  
High Resistance ◽  
Fungal Pathogens ◽  
Selection Process ◽  
Pathogenic Fungi ◽  
Cultivated Plants ◽  
Practical Implementation ◽  
Physiological Basis ◽  
Oil Crops ◽  
Soybean Genotypes ◽  
Genetically Determined

To improve the effectiveness of the soybeans and oil flax breeding, research to improve existing and develop new breeding methods are conducting in all-Russia Research institute of Oil Crops (Krasnodar). One of the improved methods for the soybean breeding, based on the use of sources of complexes of compensatory genes, is the CCG technology, which allows to create varieties with an increased yield of a heterotic level transmitted along the progeny for the entire life cycle of the variety. For the purpose of non-transgenic production of new traits, a theory of polyploid recombination of the genome (TPR) was formulated, which models the mechanism of the natural formation of polymorphism in the centers of origin of cultivated plants. On the basis of this theory, a method of breeding (TPR-technology) has been developed, which makes it possible to obtain recombinant reploids of soybeans and oil flax with an extended spectrum of traits. Of these reploids, the soybean lines with increased sucking force of the roots, providing high drought resistance, were distinguished; cold-resistant soybean lines, which stand in the phase of shoots of freezing to minus 5 °С; lines of oil flax with complete resistance to flax sickness of soil and high resistance to Fusarium; winter-hardy flax lines that withstand winter frosts down to minus 20–23 °С and ripen one and a half months earlier than spring sowings. Another original developed method is the ODCS-technology for isolating and selecting soybean genotypes with high resistance to fungal pathogens. The physiological basis of ODCS-technology is the blocking of osmotic nutrition of pathogenic fungi due to genetically determined increased osmotic pressure in the tissues of host plants. The practical implementation of CCG-, TPR- and ODKS-technologies in the selection process, allowed to create a whole series of soybean and oil flax varieties with improved or new traits.

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