scholarly journals CryoEM of bacterial secretion systems: A primer for microbiologists

2020 ◽  
Author(s):  
Trishant R. Umrekar ◽  
Eli Cohen ◽  
Tina Drobnič ◽  
Nayim Gonzalez‐Rodriguez ◽  
Morgan Beeby
Keyword(s):  
Secretion Systems ◽  
Bacterial Secretion

The ABCs and 123s of Bacterial Secretion Systems in Plant Pathogenesis

2014 ◽  
Vol 52 (1) ◽  
pp. 317-345 ◽  
Author(s):  
Jeff H. Chang ◽  
Darrell Desveaux ◽  
Allison L. Creason
Keyword(s):  
Secretion Systems ◽  
Plant Pathogenesis ◽  
Bacterial Secretion

Using Cryo-EM to Investigate Bacterial Secretion Systems

2018 ◽  
Vol 72 (1) ◽  
pp. 231-254 ◽  
Author(s):  
Chiara Rapisarda ◽  
Matteo Tassinari ◽  
Francesca Gubellini ◽  
Rémi Fronzes
Keyword(s):  
Electron Microscopy ◽  
Particle Analysis ◽  
Single Particle Analysis ◽  
Secretion Systems ◽  
Extracellular Milieu ◽  
Cryo Electron Microscopy ◽  
Bacterial Fitness ◽  
High Resolution Images ◽  
The Impact ◽  
Bacterial Secretion

Bacterial secretion systems are responsible for releasing macromolecules to the extracellular milieu or directly into other cells. These membrane complexes are associated with pathogenicity and bacterial fitness. Understanding of these large assemblies has exponentially increased in the last few years thanks to electron microscopy. In fact, a revolution in this field has led to breakthroughs in characterizing the structures of secretion systems and other macromolecular machineries so as to obtain high-resolution images of complexes that could not be crystallized. In this review, we give a brief overview of structural advancements in the understanding of secretion systems, focusing in particular on cryo–electron microscopy, whether tomography or single-particle analysis. We describe how such techniques have contributed to knowledge of the mechanism of macromolecule secretion in bacteria and the impact they will have in the future.

scholarly journals Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol

2013 ◽  
Vol 9 (6) ◽  
pp. e1003400 ◽  
Author(s):  
Cierra N. Casson ◽  
Alan M. Copenhaver ◽  
Erin E. Zwack ◽  
Hieu T. Nguyen ◽  
Till Strowig ◽  
...  
Keyword(s):  
Secretion Systems ◽  
Bacterial Secretion
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