scholarly journals A dual functional redox enzyme maturation protein for respiratory and assimilatory nitrate reductases in bacteria

2019 ◽  
Vol 111 (6) ◽  
pp. 1592-1603 ◽  
Author(s):  
Benjamin J. Pinchbeck ◽  
Manuel J. Soriano‐Laguna ◽  
Matthew J. Sullivan ◽  
Victor M. Luque‐Almagro ◽  
Gary Rowley ◽  
...  
Keyword(s):  
Redox Enzyme ◽  
Dual Functional ◽  
Enzyme Maturation ◽  
Maturation Protein ◽  
Nitrate Reductases

scholarly journals ‘Come into the fold’: A comparative analysis of bacterial redox enzyme maturation protein members of the NarJ subfamily

2014 ◽  
Vol 1838 (12) ◽  
pp. 2971-2984 ◽  
Author(s):  
Catherine S. Chan ◽  
Denice C. Bay ◽  
Thorin G.H. Leach ◽  
Tara M.L. Winstone ◽  
Lalita Kuzniatsova ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Redox Enzyme ◽  
Enzyme Maturation ◽  
Maturation Protein

Sequence analysis of bacterial redox enzyme maturation proteins (REMPs)

2004 ◽  
Vol 50 (4) ◽  
pp. 225-238 ◽  
Author(s):  
Raymond J Turner ◽  
Andriyka L Papish ◽  
Frank Sargent
Keyword(s):  
Nitrate Reductase ◽  
Protein Transport ◽  
Redox Enzyme ◽  
Respiratory Enzymes ◽  
Enzyme Maturation ◽  
Maturation Protein ◽  
Tat System ◽  
Folded Proteins ◽  
Sequence Relationships ◽  
Substrate Proteins

The twin-arginine protein transport (Tat) system is a remarkable molecular machine dedicated to the translocation of fully folded proteins across energy-transducing membranes. Complex cofactor-containing Tat substrates acquire their cofactors prior to export, and substrate proteins actually require to be folded before transport can proceed. Thus, it is very likely that mechanisms exist to prevent wasteful export of immature Tat substrates or to curb competition between immature and mature substrates for the transporter. Here we assess the primary sequence relationships between the accessory proteins implicated in this process during assembly of key respiratory enzymes in the model prokaryote Escherichia coli. For each respiratory enzyme studied, a redox enzyme maturation protein (REMP) was assigned. The main finding from this review was the hitherto unexpected link between the Tat-linked REMP DmsD and the nitrate reductase biosynthetic protein NarJ. The evolutionary link between Tat transport and cofactor insertion processes is discussed.Key words: Tat translocase, twin-arginine leader, hydrogenase, nitrate reductase, TMAO reductase, DMSO reductase, formate dehydrogenase, Tor, Dms, Hya, Hyb, Fdh, Nap.

An extremely SAD case: structure of a putative redox-enzyme maturation protein fromArchaeoglobus fulgidusat 3.4 Å resolution

2007 ◽  
Vol 63 (3) ◽  
pp. 348-354 ◽  
Author(s):  
Olga Kirillova ◽  
Maksymilian Chruszcz ◽  
Igor A. Shumilin ◽  
Tatiana Skarina ◽  
Elena Gorodichtchenskaia ◽  
...  
Keyword(s):  
Redox Enzyme ◽  
Enzyme Maturation ◽  
Maturation Protein ◽  
Case Structure

Dual-Function, Light Switchable Cobalt Catalysis via Active Site Metamorphosis

2019 ◽  
Author(s):  
Enrico Bergamaschi ◽  
Frédéric Beltran ◽  
Christopher Teskey
Keyword(s):  
Visible Light ◽  
Active Site ◽  
Catalytic Site ◽  
Dual Function ◽  
Catalytic Systems ◽  
Hydride Complex ◽  
Dual Functional ◽  
Multiple Processes ◽  
Olefin Migration

<p></p><p></p><p>Switchable catalysis offers opportunities to control the rate or selectivity of a reaction <i>via</i> a stimulus such as pH or light. However, few examples of switchable catalytic systems that can facilitate multiple processes exist. Here we report a rare example of such dual-functional, switchable catalysis. Featuring an easily prepared, bench-stable cobalt(I) hydride complex in conjunction with pinacolborane, we can completely alter the reaction outcome between two widely employed transformations – olefin migration and hydroboration – with visible light as the sole trigger. This dichotomy arises from ligand photodissociation which leads to metamorphosis of the active catalytic site, resulting in divergent mechanistic pathways.</p><p></p><p></p>

Dual Functional Interactions of Substance P and Opioids in Nociceptive Transmission: Review and Reconciliation

Analgesia ◽  
1998 ◽  
Vol 3 (4) ◽  
pp. 259-268 ◽  
Author(s):  
Iwona Maszczynska ◽  
Andrzej W. Lipkowski ◽  
Daniel B. Carr ◽  
Richard M. Kream
Keyword(s):  
Substance P ◽  
Nociceptive Transmission ◽  
Functional Interactions ◽  
Dual Functional

scholarly journals Thermo- and Photoresponsive Behaviors of Dual-Stimuli-Responsive Organogels Consisting of Homopolymers of Coumarin-Containing Methacrylate

Polymers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 329
Author(s):  
Seidai Okada ◽  
Eriko Sato
Keyword(s):  
Functional Group ◽  
Solution Temperature ◽  
Stimuli Responsive ◽  
Critical Solution Temperature ◽  
Equilibrium Degree ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Dual Functional ◽  
Wide Range ◽  
Increasing Temperature

Coumarin-containing vinyl homopolymers, such as poly(7-methacryloyloxycoumarin) (P1a) and poly(7-(2′-methacryloyloxyethoxy)coumarin) (P1b), show a lower critical solution temperature (LCST) in chloroform, which can be controlled by the [2 + 2] photochemical cycloaddition of the coumarin moiety, and they are recognized as monofunctional dual-stimuli-responsive polymers. A single functional group of monofunctional dual-stimuli-responsive polymers responds to dual stimuli and can be introduced more uniformly and densely than those of dual-functional dual-stimuli-responsive polymers. In this study, considering a wide range of applications, organogels consisting of P1a and P1b, i.e., P1a-gel and P1b-gel, respectively, were synthesized, and their thermo- and photoresponsive behaviors in chloroform were investigated in detail. P1a-gel and P1b-gel in a swollen state (transparent) exhibited phase separation (turbid) through a temperature jump and reached a shrunken state (transparent), i.e., an equilibrium state, over time. Moreover, the equilibrium degree of swelling decreased non-linearly with increasing temperature. Furthermore, different thermoresponsive sites were photopatterned on the organogel through the photodimerization of the coumarin unit. The organogels consisting of homopolymers of coumarin-containing methacrylate exhibited unique thermo- and photoresponsivities and behaved as monofunctional dual-stimuli-responsive organogels.

Sign in / Sign up

Export Citation Format

Share Document