scholarly journals AlteringNeurospora crassaMOB2A exposes its functions in development and affects its interaction with the NDR kinase COT1

2018 ◽  
Vol 108 (6) ◽  
pp. 641-660 ◽  
Author(s):  
Liran Aharoni-Kats ◽  
Einat Zelinger ◽  
She Chen ◽  
Oded Yarden
Keyword(s):  
Ndr Kinase

scholarly journals Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance

2013 ◽  
Vol 27 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Z. Wu ◽  
T. Sawada ◽  
K. Shiba ◽  
S. Liu ◽  
T. Kanao ◽  
...  
Keyword(s):  
Quality Control ◽  
Kinase Signaling ◽  
Mitochondrial Quality Control ◽  
Ndr Kinase

scholarly journals NDR Kinase Sid2 Drives Anillin-like Mid1 from the Membrane to Promote Cytokinesis and Medial Division Site Placement

2019 ◽  
Vol 29 (6) ◽  
pp. 1055-1063.e2 ◽  
Author(s):  
Alaina H. Willet ◽  
Ashley K. DeWitt ◽  
Janel R. Beckley ◽  
Dawn M. Clifford ◽  
Kathleen L. Gould
Keyword(s):  
Division Site ◽  
Ndr Kinase

scholarly journals Structure of the Ca2+/S100B/NDR Kinase Peptide Complex:  Insights into S100 Target Specificity and Activation of the Kinase

Biochemistry ◽  
2006 ◽  
Vol 45 (5) ◽  
pp. 1536-1536
Author(s):  
Shibani Bhattacharya ◽  
Edward Large ◽  
Claus W. Heizmann ◽  
Brian A. Hemmings ◽  
Walter J. Chazin
Keyword(s):  
Target Specificity ◽  
Peptide Complex ◽  
Ndr Kinase

scholarly journals MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis

2011 ◽  
Vol 31 (17) ◽  
pp. 3603-3615 ◽  
Author(s):  
Y. Zhou ◽  
Y. Adolfs ◽  
W. W. M. P. Pijnappel ◽  
S. J. Fuller ◽  
R. C. Van der Schors ◽  
...  
Keyword(s):  
Negative Regulator ◽  
Kinase Signaling ◽  
Ndr Kinase

PKL01, an Ndr kinase homologue in plant, shows tyrosine kinase activity

2012 ◽  
Vol 152 (4) ◽  
pp. 347-353 ◽  
Author(s):  
S. Katayama ◽  
Y. Sugiyama ◽  
N. Hatano ◽  
T. Terachi ◽  
N. Sueyoshi ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Kinase Activity ◽  
Tyrosine Kinase Activity ◽  
Kinase Homologue ◽  
Ndr Kinase

scholarly journals NDR Kinase Is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis

2008 ◽  
Vol 18 (23) ◽  
pp. 1889-1895 ◽  
Author(s):  
Anton Vichalkovski ◽  
Ekaterina Gresko ◽  
Hauke Cornils ◽  
Alexander Hergovich ◽  
Debora Schmitz ◽  
...  
Keyword(s):  
Receptor Stimulation ◽  
Fas Receptor ◽  
Ndr Kinase

scholarly journals The N-terminal region of theNeurospora NDR kinase COT1 regulates morphology via its interactions with MOB2A/B

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Carmit Ziv ◽  
Daria Feldman ◽  
Liran Aharoni-Kats ◽  
She Chen ◽  
Yi Liu ◽  
...  
Keyword(s):  
Terminal Region ◽  
Ndr Kinase

scholarly journals Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Rosalind Norkett ◽  
Urko del Castillo ◽  
Wen Lu ◽  
Vladimir I Gelfand
Keyword(s):  
Neurite Outgrowth ◽  
Neuronal Development ◽  
Live Imaging ◽  
Biochemical Methods ◽  
Interphase Cells ◽  
Ndr Kinase

Correct neuronal development requires tailored neurite outgrowth. Neurite outgrowth is driven in part by microtubule-sliding – the transport of microtubules along each other. We have recently demonstrated that a ‘mitotic’ kinesin-6 (Pavarotti in Drosophila) effectively inhibits microtubule-sliding and neurite outgrowth. However, mechanisms regulating Pavarotti itself in interphase cells and specifically in neurite outgrowth are unknown. Here, we use a combination of live imaging and biochemical methods to show that the inhibition of microtubule-sliding by Pavarotti is controlled by phosphorylation. We identify the Ser/Thr NDR kinase Tricornered (Trc) as a Pavarotti-dependent regulator of microtubule sliding in neurons. Further, we show that Trc-mediated phosphorylation of Pavarotti promotes its interaction with 14-3-3 proteins. Loss of 14-3-3 prevents Pavarotti from associating with microtubules. Thus, we propose a pathway by which microtubule-sliding can be up- or downregulated in neurons to control neurite outgrowth, and establish parallels between microtubule-sliding in mitosis and post-mitotic neurons.

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