scholarly journals Recycling factors for ribosome disassembly in the apicoplast and mitochondrion ofPlasmodium falciparum

2013 ◽  
Vol 88 (5) ◽  
pp. 891-905 ◽  
Author(s):  
Ankit Gupta ◽  
Snober S. Mir ◽  
Katherine E. Jackson ◽  
Erin E. Lim ◽  
Priyanka Shah ◽  
...  
Keyword(s):  
Ofplasmodium Falciparum ◽  
Ribosome Disassembly

scholarly journals Analysis ofPlasmodium falciparum varGenes Expressed in Children from Papua New Guinea

2009 ◽  
Vol 200 (3) ◽  
pp. 347-356 ◽  
Author(s):  
Nicole Falk ◽  
Mirjam Kaestli ◽  
Weihong Qi ◽  
Michael Ott ◽  
Kay Baea ◽  
...  
Keyword(s):  
Papua New Guinea ◽  
New Guinea ◽  
Ofplasmodium Falciparum

scholarly journals Antibodies against Ribosomal Phosphoprotein P0 ofPlasmodium falciparum Protect Mice against Challenge with Plasmodium yoelii

2000 ◽  
Vol 68 (7) ◽  
pp. 4312-4318 ◽  
Author(s):  
Sanchita Chatterjee ◽  
Subhash Singh ◽  
Rashmi Sohoni ◽  
Nevil J. Singh ◽  
Akhil Vaidya ◽  
...  
Keyword(s):  
Amino Acids ◽  
Deae Cellulose ◽  
Plasmodium Yoelii ◽  
Malarial Parasite ◽  
Immunization Schedule ◽  
Ofplasmodium Falciparum ◽  
P0 Protein ◽  
Recombinant Polypeptides ◽  
Blocking Antibodies ◽  
35 Kda Protein

ABSTRACT Antibodies against the Plasmodium falciparum P0 ribosomal phosphoprotein (PfP0) have been detected exclusively but extensively in malaria-immune persons. Polyclonal rabbit and mice sera were raised against two recombinant polypeptides of P. falciparum P0 protein, PfP0N and PfP0C, covering amino acids 17 to 61 and the remaining amino acids 61 to 316, respectively. Sera against both these domains detected a 35-kDa protein fromPlasmodium yoelii subsp. yoelii, a rodent malarial parasite, and stained the surface of merozoites in immunofluorescence assays. Total immunoglobulin G (IgG) purified from rabbit and mouse anti-PfP0 sera by ammonium sulfate and DEAE-cellulose chromatography was used for passive transfer experiments in mice. Mice passively immunized with both anti-PfP0N and anti-PfP0C showed distinctly lower levels of parasitemia than control mice. With immunizations on days −1, 0, 1, 3, and 5, about 50% of both sets of mice receiving anti-PfP0N and anti-PfP0C cleared the lethal 17XL strain of P. yoelii and revived by day 25. All the control mice died by day 10. By extending the immunization schedule, the survival period of the mice could be extended for every mouse that received anti-PfP0 IgG. These data demonstrate the cross-protection of the anti-PfP0 IgG and establish parasite P0 protein as a target for invasion-blocking antibodies.

scholarly journals Ultrastructure and function of mitochondria in gametocytic stage ofPlasmodium falciparum

Parasite ◽  
2000 ◽  
Vol 7 (1) ◽  
pp. 19-26 ◽  
Author(s):  
J. Krungkrai ◽  
P. Prapunwattana ◽  
S.R. Krungkrai
Keyword(s):  
Ofplasmodium Falciparum ◽  
Ultrastructure And Function ◽  
And Function

Exploration of new drug-like inhibitors for serine/threonine protein phosphatase 5 ofPlasmodium falciparum: a docking and simulation study

2015 ◽  
Vol 33 (11) ◽  
pp. 2421-2441 ◽  
Author(s):  
Saurabh Gupta ◽  
Alka Jadaun ◽  
Himansu Kumar ◽  
Utkarsh Raj ◽  
Pritish Kumar Varadwaj ◽  
...  
Keyword(s):  
Simulation Study ◽  
Protein Phosphatase ◽  
Protein Phosphatase 5 ◽  
New Drug ◽  
Ofplasmodium Falciparum
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