scholarly journals A yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation

2012 ◽  
Vol 87 (2) ◽  
pp. 284-300 ◽  
Author(s):  
Alain J. Kemp ◽  
Russell Betney ◽  
Luca Ciandrini ◽  
Alexandra C. M. Schwenger ◽  
M. Carmen Romano ◽  
...  
Keyword(s):  
Yeast Trna ◽  
Pseudohyphal Growth

scholarly journals Structure and function of the yeast tRNA ligase gene.

1988 ◽  
Vol 263 (7) ◽  
pp. 3171-3176 ◽  
Author(s):  
S K Westaway ◽  
E M Phizicky ◽  
J Abelson
Keyword(s):  
Structure And Function ◽  
Yeast Trna ◽  
And Function

scholarly journals Cysteine of sequence motif VI is essential for nucleophilic catalysis by yeast tRNA m5C methyltransferase

RNA ◽  
2007 ◽  
Vol 13 (7) ◽  
pp. 967-973 ◽  
Author(s):  
H. Walbott ◽  
C. Husson ◽  
S. Auxilien ◽  
B. Golinelli-Pimpaneau
Keyword(s):  
Sequence Motif ◽  
Nucleophilic Catalysis ◽  
Yeast Trna

Proteome changes during yeast-like and pseudohyphal growth in the biofilm-forming yeast Pichia fermentans

Amino Acids ◽  
2015 ◽  
Vol 47 (6) ◽  
pp. 1091-1106 ◽  
Author(s):  
Biancaelena Maserti ◽  
Alessandra Podda ◽  
Lucia Giorgetti ◽  
Renata Del Carratore ◽  
Didier Chevret ◽  
...  
Keyword(s):  
Pseudohyphal Growth ◽  
Proteome Changes

scholarly journals The TOR Signal Transduction Cascade Controls Cellular Differentiation in Response to Nutrients

2001 ◽  
Vol 12 (12) ◽  
pp. 4103-4113 ◽  
Author(s):  
N. Shane Cutler ◽  
Xuewen Pan ◽  
Joseph Heitman ◽  
Maria E. Cardenas
Keyword(s):  
Signal Transduction ◽  
Protein Kinases ◽  
Protein Phosphatase ◽  
Nutrient Sensing ◽  
Yeast Cells ◽  
Regulatory Subunit ◽  
Growth Defect ◽  
Tor Pathway ◽  
Pseudohyphal Growth ◽  
Pseudohyphal Differentiation

Rapamycin binds and inhibits the Tor protein kinases, which function in a nutrient-sensing signal transduction pathway that has been conserved from the yeast Saccharomyces cerevisiaeto humans. In yeast cells, the Tor pathway has been implicated in regulating cellular responses to nutrients, including proliferation, translation, transcription, autophagy, and ribosome biogenesis. We report here that rapamycin inhibits pseudohyphal filamentous differentiation of S. cerevisiae in response to nitrogen limitation. Overexpression of Tap42, a protein phosphatase regulatory subunit, restored pseudohyphal growth in cells exposed to rapamycin. The tap42-11 mutation compromised pseudohyphal differentiation and rendered it resistant to rapamycin. Cells lacking the Tap42-regulated protein phosphatase Sit4 exhibited a pseudohyphal growth defect and were markedly hypersensitive to rapamycin. Mutations in other Tap42-regulated phosphatases had no effect on pseudohyphal differentiation. Our findings support a model in which pseudohyphal differentiation is controlled by a nutrient-sensing pathway involving the Tor protein kinases and the Tap42–Sit4 protein phosphatase. Activation of the MAP kinase or cAMP pathways, or mutation of the Sok2 repressor, restored filamentation in rapamycin treated cells, supporting models in which the Tor pathway acts in parallel with these known pathways. Filamentous differentiation of diverse fungi was also blocked by rapamycin, demonstrating that the Tor signaling cascade plays a conserved role in regulating filamentous differentiation in response to nutrients.

scholarly journals Characterization of a temperature-sensitive mutation that impairs the function of yeast tRNA nucleotidyltransferase

Yeast ◽  
2008 ◽  
Vol 25 (3) ◽  
pp. 219-233 ◽  
Author(s):  
Xunying Shan ◽  
Tara A. Russell ◽  
Scott M. Paul ◽  
David B. Kushner ◽  
Paul B. M. Joyce
Keyword(s):  
Temperature Sensitive ◽  
Yeast Trna ◽  
Temperature Sensitive Mutation

scholarly journals The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4

RNA ◽  
2007 ◽  
Vol 13 (3) ◽  
pp. 404-413 ◽  
Author(s):  
M. L. Wilkinson ◽  
S. M. Crary ◽  
J. E. Jackman ◽  
E. J. Grayhack ◽  
E. M. Phizicky
Keyword(s):  
Yeast Trna

STRUCTURE OF YEAST tRNA PRECURSORS CONTAINING INTERVENING SEQUENCES

1979 ◽  
pp. 69-84 ◽  
Author(s):  
Hyen S. Kang ◽  
Richard C. Ogden ◽  
Gayle Knapp ◽  
Craig L. Peebles ◽  
John Abelson
Keyword(s):  
Yeast Trna ◽  
Intervening Sequences

scholarly journals A Stress-Responsive Signaling Network Regulating Pseudohyphal Growth and Ribonucleoprotein Granule Abundance in Saccharomyces cerevisiae

Genetics ◽  
2019 ◽  
Vol 213 (2) ◽  
pp. 705-720 ◽  
Author(s):  
Nebibe Mutlu ◽  
Daniel T. Sheidy ◽  
Angela Hsu ◽  
Han Seol Jeong ◽  
Katherine J. Wozniak ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Signaling Network ◽  
Pseudohyphal Growth
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