Population differences in the length and early‐life dynamics of telomeres among European pied flycatchers

B[a]P–DNA binding in early life-stages of Atlantic tomcod: population differences and chromium modulation

Marine Environmental Research ◽

10.1016/j.marenvres.2004.03.024 ◽

2004 ◽

Vol 58 (2-5) ◽

pp. 383-388 ◽

Cited By ~ 7

Author(s):

C. Sorrentino ◽

N.K. Roy ◽

R.C. Chambers ◽

S.C. Courtenay ◽

I. Wirgin

Keyword(s):

Dna Binding ◽

Early Life ◽

Life Stages ◽

Population Differences ◽

Early Life Stages

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Population differences in the length, early-life dynamics, and heritability of telomeres among European pied flycatchers

10.1101/2021.03.16.435615 ◽

2021 ◽

Author(s):

Tiia Karkkainen ◽

Toni Laaksonen ◽

Malcolm Burgess ◽

Alejandro Cantarero ◽

Jesus Martinez-Padilla ◽

...

Keyword(s):

Telomere Length ◽

Early Life ◽

Large Scale ◽

Later Life ◽

Sub Saharan Africa ◽

Pied Flycatcher ◽

Breeding Period ◽

Population Differences ◽

Telomere Shortening ◽

Shortening Rate

Telomere length and shortening rate are increasingly used as biomarkers for long-term costs in ecological and evolutionary studies because of their relationships with survival and fitness. Telomere length can be heritable, but both early-life conditions and later-life stressors can create variation in telomere shortening rate. Studies on between-population telomere length and dynamics are mostly lacking, despite the expectation that populations exposed to varying environmental constraints would present divergent telomere length patterns. Pied flycatcher (Ficedula hypoleuca) is a passerine bird spending the non-breeding period in sub-Saharan Africa but breeding across Eurasia (from Spain to western Siberia). Populations show marked differences in migration distance, genetics, breeding parameters, and egg components. We studied the large-scale variation of telomere length, early-life dynamics and heritability in the pied flycatcher by comparing six European populations across a north-south gradient (Finland, Estonia, England and Spain). There were clear population differences in telomere length, with English birds having the longest telomeres, followed by Spanish and lastly by Estonian and Finnish birds. Early-life telomere shortening rate tended to vary between populations, and faster nestling growth affected telomeres more negatively in northern than southern populations. The heritability of telomere length was moderate (h2 = 0.34 - 0.40), with stronger heritability to paternal than maternal telomere length. There was also evidence indicating that the level of paternal heritability could differ between populations. While the sources of between-population differences in telomere-related biology remain to be identified (i.e. genetics, environmental factors), our study illustrates the need to expand telomere studies at the between-population level.

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Population differences in early life-history traits in grayling

Journal of Evolutionary Biology ◽

10.1046/j.1420-9101.2000.00242.x ◽

2000 ◽

Vol 13 (6) ◽

pp. 897-905 ◽

Cited By ~ 96

Author(s):

T. O. Haugen ◽

L. A. Vollestad

Keyword(s):

Life History ◽

Early Life ◽

Life History Traits ◽

Early Life History ◽

Population Differences

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The Early Life of Thomas Hardy 1840–1891

10.1017/cbo9781139060776 ◽

2009 ◽

Cited By ~ 5

Author(s):

Florence Emily Hardy

Keyword(s):

Early Life ◽

Thomas Hardy

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Chemically Contaminated Eel Fed to Pregnant and Lactating Mouse Dams Causes Hyperactivity in Their Offspring

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000288 ◽

2016 ◽

Vol 86 (1-2) ◽

pp. 36-47 ◽

Cited By ~ 2

Author(s):

Imen Dridi ◽

Nidhal Soualeh ◽

Torsten Bohn ◽

Rachid Soulimani ◽

Jaouad Bouayed

Keyword(s):

Open Field ◽

Early Life ◽

Home Cage ◽

Anguilla Anguilla ◽

Acetylcholinesterase Activity ◽

Female Offspring ◽

Significant Inhibition ◽

Standard Diet ◽

Early Life Exposure ◽

Cage Test

Abstract.This study examined whether perinatal exposure to polluted eels (Anguilla anguilla L.) induces changes in the locomotor activity of offspring mice across lifespan (post-natal days (PNDs) 47 – 329), using the open field and the home cage activity tests. Dams were exposed during gestation and lactation, through diets enriched in eels naturally contaminated with pollutants including PCBs. Analysis of the eel muscle focused on the six non-dioxin-like (NDL) indicator PCBs (Σ6 NDL-PCBs: 28, 52, 101, 138, 153 and 180). Four groups of dams (n = 10 per group) received either a standard diet without eels or eels (0.8 mg/kg/day) containing 85, 216, or 400 ng/kg/day of ϵ6 NDL-PCBs. The open field test showed that early-life exposure to polluted eels increased locomotion in female offspring of exposed dams but not in males, compared to controls. This hyperlocomotion appeared later in life, at PNDs 195 and 329 (up to 32 % increase, p < 0.05). In addition, overactivity was observed in the home cage test at PND 305: exposed offspring females showed a faster overall locomotion speed (3.6 – 4.2 cm/s) than controls (2.9 cm/s, p <0.05); again, males remained unaffected. Covered distances in the home cage test were only elevated significantly in offspring females exposed to highest PCB concentrations (3411 ± 590 cm vs. 1377 ± 114 cm, p < 0.001). These results suggest that early-life exposure to polluted eels containing dietary contaminants including PCBs caused late, persistent and gender-dependent neurobehavioral hyperactive effects in offspring mice. Furthermore, female hyperactivity was associated with a significant inhibition of acetylcholinesterase activity in the hippocampus and the prefrontal cortex.

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