scholarly journals Effect of locally produced complementary foods on fat‐free mass, linear growth, and iron status among Kenyan infants: A randomized controlled trial

2019 ◽  
Vol 15 (4) ◽  
Author(s):  
Silvenus O. Konyole ◽  
Selina A. Omollo ◽  
John N. Kinyuru ◽  
Jutta K.H. Skau ◽  
Bethwell O. Owuor ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Linear Growth ◽  
Iron Status ◽  
Controlled Trial ◽  
Fat Free Mass ◽  
Complementary Foods ◽  
Randomized Controlled

scholarly journals A Randomized Controlled Trial of Daily and Weekly Iron Supplementations for Improving Iron Status in the Infants

2021 ◽  
Author(s):  
Nalinee Pattrakornkul ◽  
Parichaya Ngamcherdtrakul ◽  
Warawut Kriangburapa ◽  
Siriporn Tangjaturonrasme ◽  
Ramorn Yampratoom
Keyword(s):  
Randomized Controlled Trial ◽  
Iron Deficiency ◽  
Iron Supplementation ◽  
Iron Status ◽  
Controlled Trial ◽  
Daily Group ◽  
Randomized Controlled ◽  
The Mean ◽  
Mean Differences ◽  
Weekly Group

Abstract Background: Iron deficiency anemia screening and iron supplementation in infants aged 6-12 months are recommended in the Guideline in Child Health Supervision. This study aims to evaluate the effectiveness of weekly iron supplementation compared with daily supplementation in improving the iron status in infants.Methods: A single-blind randomized controlled trial was conducted in infants aged 6 months visiting the Well Child Clinic between May 2019 and November 2020 at Burapha University Hospital, Chonburi, Thailand. The intervention consisted of either daily or weekly iron supplementation combined with iron-rich complementary food promotion for six months. The outcomes were the differences of serum ferritin and hematological variables before and after being iron supplemented. Results: Sixty-nine six-month-old healthy infants were randomized to receive either 10 mg Fe/day (daily group) or 30 mg Fe/week (weekly group). Forty-five infants (daily group; n = 24 and weekly group; n = 21) completed the intervention. After the six-month period of iron supplementation, the mean differences of serum ferritin in the daily and the weekly group were 8.78±37.21 and -13.05 ±17.53 ng/mL, respectively (95%CI: 4.54, 39.12; P=0.015). The mean differences of hemoglobin in the daily and the weekly group were 0.58±0.82 and 0.08±0.59 g/dL, respectively (95%CI: 0.06, 0.93; P=0.026). Daily supplementation could prevent iron deficiency more than weekly supplementation significantly (P=0.029), particularly in the exclusive breastfeeding subgroup (P=0.032).Conclusions: Daily iron supplementation is more effective than weekly iron supplementation in improving iron status and hemoglobin level in infants, especially in the exclusively breast-feds.Trial registration: TCTR20191107001, November 7th, 2019. Retrospectively registered, http://www.thaiclinicaltrials.org

Growth and Fat-Free Mass Gain in Preterm Infants After Discharge: A Randomized Controlled Trial

PEDIATRICS ◽  
2012 ◽  
Vol 130 (5) ◽  
pp. e1215-e1221 ◽  
Author(s):  
P. Roggero ◽  
M. L. Gianni ◽  
O. Amato ◽  
N. Liotto ◽  
L. Morlacchi ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Preterm Infants ◽  
Controlled Trial ◽  
Mass Gain ◽  
Fat Free Mass ◽  
Randomized Controlled

scholarly journals Conditional cash transfer and/or lipid-based nutrient supplement targeting the first 1000 d of life increased attendance at preventive care services but did not improve linear growth in young children in rural Mali: results of a cluster-randomized controlled trial

2019 ◽  
Vol 110 (6) ◽  
pp. 1476-1490 ◽  
Author(s):  
Laura Adubra ◽  
Agnes Le Port ◽  
Yves Kameli ◽  
Sonia Fortin ◽  
Tanimoune Mahamadou ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Linear Growth ◽  
Controlled Trial ◽  
Conditional Cash Transfer ◽  
Cluster Randomized Controlled Trial ◽  
Growth Monitoring ◽  
Randomized Controlled ◽  
Nutrient Supplement ◽  
Intermediate Outcomes ◽  
Cluster Randomized

ABSTRACT Background In 2014, the World Food Programme added to an ongoing health and nutrition program named “Santé Nutritionnelle à Assise Communautaire dans la région de Kayes” (SNACK), the distribution of cash to mothers and/or lipid-based nutrient supplement (LNS) to children aged 6–23 mo, conditional upon attendance at community health centers (CHCs) during the first 1000 d of life. Objective We evaluated the additional impact of the distribution of cash and/or LNS on mean height-for-age z scores (HAZ; primary outcome), stunting (HAZ < −2), and on intermediate outcomes along the program impact pathways. Methods In a cluster-randomized controlled trial using a 2 × 2 factorial design, 76 CHCs were randomly assigned to deliver either SNACK, SNACK + Cash, SNACK + LNS, or SNACK + Cash + LNS. Cross-sectional surveys among 12- to 42-mo-old children and their mothers were conducted at baseline (2013, n = 5046) and at endline (2016, n = 5098). Results Factorial analysis showed no interaction between cash and LNS treatments for HAZ, but found an antagonistic interaction for stunting (OR: 1.55; 95% CI: 1.05, 2.31; P = 0.03). There were no impacts of the cash, LNS, or cash + LNS treatments, compared with the SNACK alone, on either HAZ or stunting (treatment × time interaction). There were significant impacts of the LNS and cash + LNS treatments on attendance at ≥1 growth monitoring (GM) session (OR: 3.95; 95% CI: 1.69, 9.24; OR: 3.90; 95% CI: 1.73, 8.81, respectively) and half the expected sessions (OR: 4.72; 95% CI: 1.47, 15.17; OR: 5.25; 95% CI: 1.82, 15.11, respectively), mothers’ knowledge on importance of GM (OR: 1.98; 95% CI: 1.16, 3.39; OR: 3.12; 95% CI: 1.60, 6.09, respectively), and, only for the LNS group, appropriate timing for complementary feeding (OR: 1.62; 95% CI: 1.09, 2.41). Conclusions Implementation constraints and suboptimal participation in program activities may explain the lack of impact on child linear growth in this rural region of Mali. This trial was registered at www.isrctn.com as ISRCTN08435964.

scholarly journals Food-based strategies improve iron status in toddlers: a randomized controlled trial

2009 ◽  
Vol 90 (6) ◽  
pp. 1541-1551 ◽  
Author(s):  
Ewa A Szymlek-Gay ◽  
Elaine L Ferguson ◽  
Anne-Louise M Heath ◽  
Andrew R Gray ◽  
Rosalind S Gibson
Keyword(s):  
Randomized Controlled Trial ◽  
Iron Status ◽  
Controlled Trial ◽  
Randomized Controlled
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