scholarly journals Two‐year follow‐up of a postpartum weight loss intervention: Results from a randomized controlled trial

2017 ◽  
Vol 14 (2) ◽  
Author(s):  
Ena Huseinovic ◽  
Fredrik Bertz ◽  
Hilde Kristin Brekke ◽  
Anna Winkvist
2014 ◽  
Vol 4 (3) ◽  
pp. 127-135 ◽  
Author(s):  
N. R. Fuller ◽  
K. Williams ◽  
R. Shrestha ◽  
A. L. Ahern ◽  
C. Holzapfel ◽  
...  

2021 ◽  
pp. 1-9
Author(s):  
M. Serra-Prat ◽  
M. Terradellas ◽  
I. Lorenzo ◽  
M. Arús ◽  
E. Burdoy ◽  
...  

Background: Obesity is a risk factor for frailty and muscle weakness, so weight loss in obese older adults may prevent frailty and functional decline. Objective: To assess the safety and efficacy of a multimodal weight-loss intervention in improving functional performance and reducing frailty risk in obese older adults. Design: Randomized controlled trial with 2 parallel arms. Setting and participants: Community-dwelling obese adults aged 65-75 years with body mass index (BMI) 30-39 kg/m2. Intervention: 6-month multimodal intervention based on diet and a physical activity program. Control group: Usual care. Main and secondary outcome measures: Frailty (Fried criteria) rate and functional performance at 6, 12, and 24 months of follow-up, respectively. Intermediate outcome measures: Weight loss, body composition changes, and metabolic and inflammatory biomarker changes. Results: N=305. The study intervention increased gait speed at 12 and 24 months of follow-up, but had no significant effect on frailty prevention. It was effective in reducing weight, BMI, fat mass, interleukin 6, and insulin resistance and improving self-reported quality of life. Conclusions: The study intervention was not demonstrated to be effective in preventing frailty in obese people aged 65-75 years at 24 months of follow-up. However, it allowed weight loss and a reduction in inflammatory and insulin resistance markers, which could have a long-term effect on frailty that requires further research.


Obesity ◽  
2017 ◽  
Vol 26 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Dale S. Bond ◽  
J. Graham Thomas ◽  
Richard B. Lipton ◽  
Julie Roth ◽  
Jelena M. Pavlovic ◽  
...  

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e339
Author(s):  
Yftach Gepner ◽  
Nir Goldstein ◽  
Ilan Shelef ◽  
Dan Schwarzfuchs ◽  
Hila Zelicha ◽  
...  

2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Ralph Maddison ◽  
Cliona Ni Mhurchu ◽  
Louise Foley ◽  
Leonard Epstein ◽  
Yannan Jiang ◽  
...  

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