scholarly journals Association between the neutrophil‐to‐lymphocyte ratio and intravesical prostatic protrusion in men with benign prostatic hyperplasia

2019 ◽  
Vol 12 (1) ◽  
pp. 62-67
Author(s):  
Mun Su Chung ◽  
Yun Jung Yang ◽  
Seung Hwan Lee ◽  
Byung Il Yoon
2021 ◽  
pp. 1-6
Author(s):  
Jung Yoon Kang ◽  
Jae Duck Choi ◽  
Jeong Man Cho ◽  
Tag Keun Yoo ◽  
Yeon Won Park ◽  
...  

<b><i>Introduction:</i></b> The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) have recently been proposed as easily accessible inflammatory biomarkers and as surrogate markers for metabolic disease, cardiovascular disease, and malignancies, including prostate cancer. However, scant studies have investigated the association of NLR, PLR, and LMR with benign prostatic hyperplasia (BPH). <b><i>Methods:</i></b> Data from 8,727 middle-aged men who had participated in a health checkup were analyzed. BPH was defined as prostate volume ≥30 mL, International Prostate Symptom Score &#x3e; 7, and maximal flow rate &#x3c;15 mL/s. Propensity score matching was considered for 269 men with BPH (cases), and 7,136 men with no BPH (controls), but ultimately, propensity scores were matched at a 2:1 ratio of controls to cases (538 men in the control group and 269 men in the case group). <b><i>Results:</i></b> After propensity score matching, age, International Index of Erectile Function-5, testosterone, and number of metabolic syndrome component variables were evenly distributed and did not differ significantly between the groups. After matching, PLR and LMR were not significantly different between the 2 groups. However, NLR was significantly higher in the case group than in the control group (median [interquartile range]: 1.4 [1.1; 1.8] vs. 1.5 [1.2; 1.9]; <i>p</i> = 0.024) after matching. <b><i>Conclusion:</i></b> High NLR was significantly associated with the presence of BPH. Our results suggest the possible effect of inflammation on BPH development. A prospective study is needed to investigate the potential role of NLR as a candidate biomarker of BPH.


Urology ◽  
2014 ◽  
Vol 84 (5) ◽  
pp. 1026-1029 ◽  
Author(s):  
Jong Wook Kim ◽  
Mi Mi Oh ◽  
Hong Seok Park ◽  
Jun Cheon ◽  
Jeong Gu Lee ◽  
...  

2018 ◽  
Vol 12 (1) ◽  
pp. 6-12 ◽  
Author(s):  
Jason Gandhi ◽  
Steven J. Weissbart ◽  
Albert N. Kim ◽  
Gunjan Joshi ◽  
Steven A. Kaplan ◽  
...  

Background: Intravesical prostatic protrusion (IPP) is a manifestation of benign prostatic hyperplasia marked by overgrowth of the prostatic median lobe into the bladder, producing bladder outlet obstruction and related storage and voiding symptoms. Methods: A MEDLINE® database search of the current literature was guided using combination of “prostate” with the following terms: intravesical prostatic protrusion, bladder trabeculation, bladder outlet obstruction, lower urinary tract symptoms, alpha blockers, transrectal ultrasonography, and prostatectomy. Results: Although IPP can be identified via a variety of imaging modalities, it is easily detected via transrectal ultrasonography (TRUS). Failing to detect IPP promptly by TRUS may result in refractory symptoms of benign prostatic hyperplasia, as the condition may not respond to typical α1-adrenoceptor antagonist therapy. In addition, depending on grade, IPP can influence outcomes and complications of prostatectomies. Conclusion: Upon report of lower urinary tract symptoms, initial performance of TRUS along with digital rectal examination prevents delay in the appropriate evaluation and management of prostatic diseases.


2015 ◽  
Vol 3 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Ghanshyam Sigdel ◽  
WK Belokar

INTRODUCTION: Intravesical prostatic protrusion is a morphological change due to excessive growth of the median and lateral lobes of the prostate into the bladder in benign prostatic hyperplasia. It causes a 'ball-valve' type of obstruction during voiding. It is a useful parameter to assess the severity of the disease process, selection of treatment modality and its possible outcome in benign prostatic hyperplasia.MATERIAL AND METHODS: A prospective, non-randomized, observational study was carried out from January 2014 to June 2014 in the Department of Urology, College of Medical Sciences, Nepal. Total of 50 patients with benign prostatic hyperplasia were evaluated to assess the correlation of intravesical prostatic protrusion with international prostate symptom score, prostate volume, maximum flow rate and post void residual urine. Correlation between parameters of interest was quantified with Pearson correlation test.RESULTS: A positive correlation was demonstrated between intravesical prostatic protrusion, international prostate symptom score, prostate volume and post void residual urine. There was a negative correlation between intravesical prostatic protrusion and maximum flow rate.CONCLUSION: Intravesical prostatic protrusion is correlated with international prostate symptom score, prostate volume, maximum flow rate, and post void residual urine volume and hence can be used to assess the severity of benign prostatic hyperplasia.Journal of Universal College of Medical Sciences Vol. 3, No. 1, 2015: 6-10


Urologiia ◽  
2017 ◽  
Vol 2_2017 ◽  
pp. 105-109
Author(s):  
G.G. Krivoborodov Krivoborodov ◽  
N.S. Efremov Efremov ◽  
A.D. Bolotov Bolotov ◽  
◽  

2016 ◽  
Vol 98 (4) ◽  
pp. 466-471 ◽  
Author(s):  
Kutan Ozer ◽  
Mustafa Ozan Horsanali ◽  
Sacit Nuri Gorgel ◽  
Burcu Ozalp Horsanali ◽  
Emin Ozbek

Sign in / Sign up

Export Citation Format

Share Document