Prevalence and Risk Factors of Urinary Incontinence and Overactive Bladder in Japanese Women

2017 ◽  
Vol 10 (3) ◽  
pp. 308-314 ◽  
Author(s):  
Sanae NINOMIYA ◽  
Kiyoko NAITO ◽  
Kyoko NAKANISHI ◽  
Hisayo OKAYAMA
Keyword(s):  
Risk Factors ◽  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Japanese Women

Prevalence and risk factors of urinary incontinence and its influence on the quality of life of Japanese women

2008 ◽  
Vol 10 (2) ◽  
pp. 151-158 ◽  
Author(s):  
Reiko Azuma ◽  
Kyoko Murakami ◽  
Mieko Iwamoto ◽  
Mayumi Tanaka ◽  
Nahoko Saita ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Urinary Incontinence ◽  
Japanese Women

scholarly journals Persistence and adherence of solifenacin treatment for Japanese women with overactive bladder

2012 ◽  
Vol 26 (1) ◽  
pp. 9 ◽  
Author(s):  
Minoru Kobayashi ◽  
Akinori Nukui ◽  
Shinsuke Kurokawa ◽  
Tatsuo Morita
Keyword(s):  
Risk Factors ◽  
Clinical Trials ◽  
Overactive Bladder ◽  
Real World ◽  
Japanese Patients ◽  
Japanese Women ◽  
Adherence Rate ◽  
Medication Persistence ◽  
Related Risk ◽  
Persistence Rate

Persistence and adherence of overactive bladder (OAB) medication have reported to be generally lower in real-world setting as compared with those in clinical trials. However, this information in Japanese population has not been well addressed. Medical records were reviewed for solifenacin as an initial treatment for 172 women with OAB symptom to examine medication persistence, switching, adherence, and the reasons for discontinuation. The associations between persistence and the reasons for discontinuation as well as concomitant conditions regarded as OAB-related risk factors were assessed. The 6-month and 1-year persistence rate of solifenacin were 39.8% and 27.8%, respectively. Consequently, 121 patients (70.3%) discontinued solifenacin, of whom 18 (14.9%) patients switched to other OAB drugs and 9 (7.4%) patients restarted solifenacin. Thus, the adherence rate was 66.8%. More women discontinued solifenacin owing to symptom resolution (41.3%) rather than unfavorable outcomes such as adverse effects (12.4%) and lack of efficacy (21.5%). However, such reason for discontinuation was not the determinant of persistence of solifenacin. There was a non-significant trend towards higher persistence for those with OAB-related risk factors. Japanese women discontinued solofenacin treatment with various reasons in real-world practice, resulting in much lower persistence as compared with clinical trials. A further prospective study in a larger cohort of patients is awaited to better assess their persistence and adherence and understand exact efficacy and tolerability of antimuscarinics for Japanese patients with OAB.

scholarly journals Assessment of Pelvic Floor Function and Quality of Life in Patients Treated for Cervical Cancer: A Multicenter Retrospective Study

2021 ◽  
pp. 1-8
Author(s):  
Sha Wang ◽  
Hongwu Wen ◽  
Yunong Gao ◽  
Qiubo Lv ◽  
Tingting Cao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cervical Cancer ◽  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Pelvic Floor ◽  
Pelvic Floor Dysfunction ◽  
Pelvic Floor Function ◽  
Floor Function

<b><i>Objectives:</i></b> Our study aimed to evaluate the quality of life (QoL) and pelvic floor function of cervical cancer (CC) patients after treatment. <b><i>Design:</i></b> This was a cross-sectional observational cohort study. <b><i>Participants:</i></b> The participants included in this study were CC patients who underwent radical hysterectomy (RH) from 2012 to 2018 at 18 medical centers across China. <b><i>Methods:</i></b> The validated versions of the Pelvic floor Distress Inventory-Short Form 20, Overactive Bladder Symptom Score, and Euro Qol Five-Dimension questionnaires were used to evaluate postoperative pelvic floor dysfunction (PFD) and QoL. <b><i>Results:</i></b> A total of 689 CC patients were enrolled. The incidence of stress urinary incontinence (SUI), incomplete urinary emptying, and constipation were 32.7, 27.7, and 28.6%, respectively. Multivariate analysis confirmed that laparoscopic RH (LRH) and vaginal wall resection greater than 3 cm were risk factors for lower urinary tract symptoms (LUTS). LRH and chemotherapy were risk factors for SUI. Chemoradiotherapy and LRH were risk factors for overactive bladder (OAB). A high body mass index and LRH were risk factors for more severe defecation symptoms. ARH and large amount of operative blood loss were risk factors for poor QoL. <b><i>Conclusion:</i></b> PFD is common in CC patients after treatment. LRH seems to increase the postoperative distress, including LUTS and defecation symptoms. Postoperative urinary incontinence and OAB are more bothersome for patients undergoing chemotherapy and radiotherapy. We recommend evaluating pelvic floor function as a standard assessment during follow-up.

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