Carriers of ABCB4 gene variants show a mild clinical course, but impaired quality of life and limited risk for cholangiocarcinoma

2020 ◽  
Vol 40 (12) ◽  
pp. 3042-3050
Author(s):  
Elsemieke Vries ◽  
Marta Mazzetti ◽  
Bart Takkenberg ◽  
Nahid Mostafavi ◽  
Hennie Bikker ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Course ◽  
Gene Variants ◽  
Abcb4 Gene ◽  
Impaired Quality

Heterozygous carriers of ABCB4 mutations show a mild clinical course, but impaired quality of life and limited risk for cholangiocarcinoma – a cohort study

2020 ◽  
Vol 73 ◽  
pp. S86
Author(s):  
Marta Mazzetti ◽  
Elsemieke de Vries ◽  
Bart Takkenberg ◽  
Nahid Mostafavi ◽  
Henny Bikker ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cohort Study ◽  
Clinical Course ◽  
Heterozygous Carriers ◽  
Impaired Quality

1276: Lower Urinary Tract Symptoms: Local Ischemia Assessed by Sonographic Findings and Correlated to Impaired Quality of Life

2006 ◽  
Vol 175 (4S) ◽  
pp. 410-411
Author(s):  
Germar M. Pinggera ◽  
Michael Mitterberger ◽  
Leo Pallwein ◽  
Peter Rehder ◽  
Ferdinand Frauscher ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Local Ischemia ◽  
Urinary Tract Symptoms ◽  
Impaired Quality ◽  
Lower Urinary

Predictors of Impaired Quality of Life and Work Disability in Patients with Systemic Diseases

2019 ◽  
Vol 09 (03) ◽  
Author(s):  
Ben Hadj Ali Emna ◽  
Bouker Ahmed ◽  
Guiga Ahmed ◽  
Ben Yahia Wissal ◽  
Atig Amira ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Work Disability ◽  
Systemic Diseases ◽  
Impaired Quality

scholarly journals Early and Late Postoperative Seizures in Meningioma Patients and Prediction by a Recent Scoring System

Cancers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 450
Author(s):  
Peter Baumgarten ◽  
Mana Sarlak ◽  
Daniel Monden ◽  
Andrea Spyrantis ◽  
Simon Bernatz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Tumor Volume ◽  
Total Risk ◽  
Increased Risk ◽  
Independent Risk Factors ◽  
Temporal Location ◽  
Meningioma Surgery ◽  
Impaired Quality

Seizures are among the most common symptoms of meningioma. This retrospective study sought to identify risk factors for early and late seizures in meningioma patients and to evaluate a modified STAMPE2 score. In 556 patients who underwent meningioma surgery, we correlated different risk factors with the occurrence of postoperative seizures. A modified STAMPE2 score was applied. Risk factors for preoperative seizures were edema (p = 0.039) and temporal location (p = 0.038). For postoperative seizures preoperative tumor size (p < 0.001), sensomotory deficit (p = 0.004) and sphenoid wing location (p = 0.032) were independent risk factors. In terms of postoperative status epilepticus; sphenoid wing location (p = 0.022), tumor volume (p = 0.045) and preoperative seizures (p < 0.001) were independent risk factors. Postoperative seizures lead to a KPS deterioration and thus an impaired quality of life (p < 0.001). Late seizures occurred in 43% of patients with postoperative seizures. The small sub-cohort of patients (2.7%) with a STAMPE2 score of more than six points had a significantly increased risk for seizures (p < 0.001, total risk 70%). We concluded that besides distinct risk factors, high scores of the modified STAMPE2 score could estimate the risk of postoperative seizures. However, it seems not transferable to our cohort

scholarly journals Predictors of urogenital distress and impaired quality of life in adult Egyptians with lower urinary tract symptoms

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Isaac Samir Wasfy ◽  
Enayat Mohamed Soltan ◽  
Hassan A. Abdelwahab ◽  
Hend Mikhail Salama
Keyword(s):  
Quality Of Life ◽  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Emotional Health ◽  
Stress Symptoms ◽  
Urinary Tract Symptoms ◽  
Impaired Quality ◽  
Lower Urinary

Abstract Background This study aims to assess the severity of lower urinary tract symptoms, and to assess predictors of impaired quality of life among Egyptian adults complain of lower urinary tract symptoms. Methods An observational cross-sectional research was done using an online anonymous poll survey. The survey was implemented through sharing on different social media applications. The survey was posted from June 1, 2020, to June 10, 2020. The overall communities of the Egyptian adults who satisfied the incorporation rules and consented to take an interest in the research were incorporated using convenience and snowball collecting methods (188 adults). A semi-structured questionnaire on socio-demographic characteristics and Arabic Urogenital Distress Inventory (UDI-6) and Incontinence Impact Questionnaire (IIQ-7) short forms were used. Results Approximately 220 Egyptian adults shared in the research but only 188 fulfilled inclusion and exclusion criteria. Approximately 92% of them had at least one symptom of lower urinary tract manifestations. Irritative symptoms presented in 65 (85.5%) of males and 102 (91.1%) of females. Stress symptoms presented in 44 (57.9%) of males and 63 (56.2%) of females with higher statistically significant mean of stress symptoms. Obstruction/discomfort symptoms presented in 51 (67.1%) of males, and 77 (68.8%) of females. Seeking help and duration of the urological problem were statistically significant independent positive predictors of UDI-6-total. The Irritative score, obstruction/discomfort score, and duration of the urological problem were statistically significant independent positive predictors of IIQ-7-total. Conclusions Urological problems are common and have an impact on the quality of life in various domains of physical activity, social relationships, travel, and emotional health.

scholarly journals Hyperhidrosis: prevalence and impact on quality of life

2018 ◽  
Vol 44 (4) ◽  
pp. 292-298 ◽  
Author(s):  
Erica Nishida Hasimoto ◽  
Daniele Cristina Cataneo ◽  
Tarcísio Albertin dos Reis ◽  
Antonio José Maria Cataneo
Keyword(s):  
Quality Of Life ◽  
Poor Quality ◽  
Cluster Sampling ◽  
Excessive Sweating ◽  
Medical Evaluation ◽  
Primary Hyperhidrosis ◽  
Systematic Cluster ◽  
The City ◽  
Impaired Quality

ABSTRACT Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. Methods: A population survey was conducted in order to identify cases of hyperhidrosis among residents in the urban area of the city, selected by systematic cluster sampling. In accordance with the census maps of the city, the sample size should be at least 4,033 participants. Ten interviewers applied a questionnaire that evaluated the presence of excessive sweating and invited the subjects who reported hyperhidrosis to be evaluated by a physician in order to confirm the diagnosis. Results: A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. Of those 85 respondents, 51 (60%) agreed to undergo medical evaluation to confirm the diagnosis and only 23 (45%) were diagnosed with primary hyperhidrosis (prevalence = 0.93%). Of the 23 subjects diagnosed with primary hyperhidrosis, 11 (48%) reported poor or very poor quality of life. Conclusions: Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life.

606 Impaired quality of life in patients with chronic hepatitis C and persistently normal aminotransferase levels

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 454-454 ◽  
Author(s):  
M VONWAGNER ◽  
J LEE ◽  
R FRIEDL ◽  
B KRONENBERGER ◽  
C SARRAZIN ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Impaired Quality
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