scholarly journals Incidence, prevalence and mortality of autoimmune hepatitis in England 1997‐2015. A population‐based cohort study

2020 ◽  
Vol 40 (7) ◽  
pp. 1634-1644 ◽  
Author(s):  
Lisbet Grønbæk ◽  
Harmony Otete ◽  
Lu Ban ◽  
Colin Crooks ◽  
Timothy Card ◽  
...  
Keyword(s):  
Cohort Study ◽  
Autoimmune Hepatitis ◽  
Population Based ◽  
Incidence Prevalence

Pregnancy Outcomes in Women with Autoimmune Hepatitis – a Nationwide Population-Based Cohort Study with Histopathology

2021 ◽  
Author(s):  
Rajani Sharma ◽  
Tracey G. Simon ◽  
Olof Stephansson ◽  
Elizabeth C. Verna ◽  
Jean Emond ◽  
...  
Keyword(s):  
Cohort Study ◽  
Autoimmune Hepatitis ◽  
Pregnancy Outcomes ◽  
Hepatitis A ◽  
Population Based

Cancer Risk in Patients with Autoimmune Hepatitis: A Nationwide Population-Based Cohort Study with Histopathology

2021 ◽  
Author(s):  
Rajani Sharma ◽  
Elizabeth C Verna ◽  
Tracey G Simon ◽  
Jonas Söderling ◽  
Hannes Hagström ◽  
...  
Keyword(s):  
Cohort Study ◽  
General Population ◽  
Cancer Risk ◽  
Autoimmune Hepatitis ◽  
Cox Regression ◽  
Population Based ◽  
Swedish Population ◽  
Non Melanoma Skin Cancer ◽  
Incident Cancer ◽  
Increased Risk

Abstract We aimed to determine the risk of incident cancer in autoimmune hepatitis (AIH) compared to the general population and siblings. AIH was defined by the presence of a medical diagnosis of AIH and a liver biopsy in a nationwide Swedish population-based cohort study. We identified 5,268 adults with AIH diagnosed 1969-2016 and 22,996 matched general population reference individuals and 4,170 sibling comparators. Using Cox regression, hazard ratios (HRs) were determined for any incident cancer and sub-types determined from the Swedish Cancer Register. During follow-up, a cancer diagnosis was made in 1,119 individuals with AIH (17.2/1000 person-years) and 4,450 reference individuals (12.0/1000 person-years). This corresponded to an HR of 1.53 (95%CI: 1.42,1.66). Cancer risk was highest in those with cirrhosis. There was a 29.18-fold increased risk of hepatocellular carcinoma (HCC) (95%CI, 17.52,48.61). The annual incidence risk of HCC in individuals with AIH who had cirrhosis was 1.1% per year. AIH was also linked to non-melanoma skin cancer (HR=2.69) and lymphoma (HR=1.89). Sibling analyses yielded similar risk estimates for any cancer (HR=1.84) and HCC (HR=23.10). AIH is associated with an increased risk of any cancer, in particular, HCC and extra-hepatic malignancies. The highest risk for cancer, especially HCC, is in patients with cirrhosis.

Incidence, prevalence, and mortality of dermatomyositis: a population‐based cohort study

2021 ◽  
Author(s):  
Vanessa L. Kronzer ◽  
Bradly A. Kimbrough ◽  
Cynthia S. Crowson ◽  
John M. Davis ◽  
Marie Holmqvist ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Incidence Prevalence

scholarly journals Incidence, prevalence and mortality of patients with psoriasis: a U.K. population-based cohort study

2016 ◽  
Vol 176 (3) ◽  
pp. 650-658 ◽  
Author(s):  
D.A. Springate ◽  
R. Parisi ◽  
E. Kontopantelis ◽  
D. Reeves ◽  
C.E.M. Griffiths ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Incidence Prevalence

scholarly journals Increased Mortality Risk in Autoimmune Hepatitis: A Nationwide Population-based Cohort Study With Histopathology

2020 ◽  
Author(s):  
Rajani Sharma ◽  
Elizabeth C. Verna ◽  
Jonas Söderling ◽  
Bjorn Roelstraete ◽  
Hannes Hagström ◽  
...  
Keyword(s):  
Cohort Study ◽  
Autoimmune Hepatitis ◽  
Mortality Risk ◽  
Hepatitis A ◽  
Population Based
Sign in / Sign up

Export Citation Format

Share Document