scholarly journals Diagnostic and prognostic assessment of suspected drug‐induced liver injury in clinical practice

2019 ◽  
Vol 40 (1) ◽  
pp. 6-17 ◽  
Author(s):  
Raúl J. Andrade ◽  
Mercedes Robles‐Díaz
Keyword(s):  
Clinical Practice ◽  
Liver Injury ◽  
Suspected Drug ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Prognostic Assessment

scholarly journals Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0189436 ◽  
Author(s):  
Valentina Peta ◽  
Chantal Tse ◽  
Hugo Perazzo ◽  
Mona Munteanu ◽  
Yen Ngo ◽  
...  
Keyword(s):  
Liver Injury ◽  
Apolipoprotein A1 ◽  
Suspected Drug ◽  
Drug Induced ◽  
Drug Induced Liver Injury

scholarly journals Drug Liver Injury Induced by Olmesartan Mediated by Autoimmune-Like Mechanism: A Case Report

2020 ◽  
Author(s):  
Manuel de la Torre-Aláez ◽  
Mercedes Iñarrairaegui
Keyword(s):  
Case Report ◽  
Liver Injury ◽  
Drug Exposure ◽  
Interesting Case ◽  
Suspected Drug ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Difficult Diagnosis ◽  
Histological Confirmation ◽  
The Relationship

Autoimmune hepatitis (AIH) was the first liver disease for which an effective therapeutic intervention was carried out, using prednisolone; its usefulness was demonstrated in several clinical trials. Nevertheless, AIH still remains a difficult diagnosis in some cases, because it is necessary to dismiss other possible diagnoses, and perhaps due to it being a heterogeneous disease. The relationship between drug-induced liver injury (DILI) and AIH is complex and not fully understood. There are three possible scenarios: (1) DILI with a strong immunoallergic component mimicking AIH; (2) AIH mimicking a DILI due to drug exposure and (3) AIH triggered by exposure to an offending drug (drug-induced AIH). Drug-induced AIH is well described and documented for some drugs such as nitrofurantoin and minocycline. Histologically distinguishing DILI from AIH remains a challenge. We present an interesting case report which met serologic criteria and histological confirmation to establish AIH, but discontinuation of a suspected drug resolved hypertransaminasaemia.

scholarly journals Case of suspected drug-induced liver injury caused by Inchinko-To

Kanzo ◽  
2011 ◽  
Vol 52 (6) ◽  
pp. 356-360
Author(s):  
Toshikuni Suda ◽  
Kazuyoshi Suzuki ◽  
Shogo Adachi ◽  
Kagemasa Kagawa ◽  
Hiroki Saito ◽  
...  
Keyword(s):  
Liver Injury ◽  
Suspected Drug ◽  
Drug Induced ◽  
Drug Induced Liver Injury
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