scholarly journals The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: Evidence and plausible mechanisms

2017 ◽  
Vol 37 (7) ◽  
pp. 936-949 ◽  
Author(s):  
Shira Zelber-Sagi ◽  
Federico Salomone ◽  
Liat Mlynarsky
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Dietary Pattern ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Mediterranean Dietary Pattern ◽  
The Mediterranean ◽  
Alcoholic Fatty Liver Disease

scholarly journals Is the Mediterranean Diet the Best Approach to NAFLD Treatment Today?

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 739
Author(s):  
Francesco Angelico ◽  
Domenico Ferro ◽  
Francesco Baratta
Keyword(s):  
Liver Disease ◽  
General Population ◽  
Fatty Liver ◽  
Mediterranean Diet ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
The Mediterranean ◽  
Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent diseases worldwide, involving about 20–30% of the general population [...]

scholarly journals Improvement in liver function after an intervention based on the Mediterranean diet in patients with non alcoholic fatty liver disease (NAFLD)

2016 ◽  
Vol 13 ◽  
pp. e57 ◽  
Author(s):  
Christina N. Katsagoni ◽  
Aggeliki Egkomiti ◽  
Mariviki Papageorgiou ◽  
Panagiota Ioannidou ◽  
Elizabeth Fragopoulou ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Function ◽  
Fatty Liver ◽  
Mediterranean Diet ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
The Mediterranean ◽  
Alcoholic Fatty Liver Disease

scholarly journals Healthy dietary pattern is inversely associated with non-alcoholic fatty liver disease in elderly

2016 ◽  
Vol 115 (12) ◽  
pp. 2189-2195 ◽  
Author(s):  
Lia Silveira Adriano ◽  
Helena Alves de Carvalho Sampaio ◽  
Soraia Pinheiro Machado Arruda ◽  
Clarissa Lima de Melo Portela ◽  
Maria Luisa Pereira de Melo ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Fatty Liver Disease ◽  
The Elderly ◽  
Alcoholic Beverages ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease ◽  
Healthy Dietary Pattern

AbstractThe prevalence of non-alcoholic fatty liver disease (NAFLD) is rising, an increase that may be associated with changes in lifestyle such as unhealthy dietary patterns. Although advanced age is a risk factor for NAFLD, no studies reporting this association in the elderly population were found. In the present study, the association between dietary patterns and NAFLD in the elderly was assessed. A study including 229 older adults was conducted. NAFLD diagnosis was defined as individuals whose ultrasound examination disclosed hepatic steatosis at any stage, in the absence of excess intake of alcoholic beverages. Dietary patterns were obtained by principal components analysis. Mean scores and standard errors of each dietary pattern were calculated for the groups with and without NAFLD, and mean scores of the two groups were compared using the Mann–Whitney U test. The prevalence ratios and 95 % CI were estimated for each tertile of the dietary pattern adherence scores using Poisson multiple regression models with robust variance. A total of 103 (45 %) elderly with NAFLD and four dietary patterns were identified: traditional, regional snacks, energy dense and healthy. Mean scores for adherence to the healthy pattern in the groups with and without NAFLD differed. NAFLD was inversely associated with greater adherence to the healthy pattern and directly associated with the regional snacks, after adjustment for confounders. In conclusion, healthy dietary pattern is inversely associated with NAFLD in elderly.

scholarly journals ‘Focus on diet quality’: A qualitative study of clinicians’ perspectives of use of the Mediterranean dietary pattern for nonalcoholic fatty liver disease

2021 ◽  
pp. 1-26
Author(s):  
Hannah L Mayr ◽  
Jaimon T Kelly ◽  
Graeme A Macdonald ◽  
Ingrid J Hickman
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Knowledge Sharing ◽  
Nonalcoholic Fatty Liver Disease ◽  
Diet Quality ◽  
Dietary Pattern ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
Mediterranean Dietary Pattern ◽  
The Mediterranean

Abstract Practice guidelines for nonalcoholic fatty liver disease (NAFLD) recommend promoting the Mediterranean dietary pattern (MDP) which is cardioprotective and may improve hepatic steatosis. This study aimed to explore multidisciplinary clinicians’ perspectives on whether the MDP is recommended in routine management of NAFLD and barriers and facilitators to its implementation in a multiethnic setting. Semistructured individual interviews were conducted with 14 clinicians (7 doctors, 3 nurses, 3 dietitians and 1 exercise physiologist) routinely managing patients with NAFLD in metropolitan hospital outpatient clinics in Australia. Interviews were audio-recorded, transcribed and analysed using thematic content analysis. Clinician’s described that lifestyle modification was their primary treatment for NAFLD and promoting diet was recognised as everyone’s role, whereby doctors and nurses raise awareness and dietitians provide individualisation. The MDP was regarded as the most evidence-based diet choice currently and was frequently recommended in routine care. Facilitators to MDP implementation in practice were: improvement in diet quality as a parallel goal to weight loss; in-depth knowledge of the dietary pattern; access to patient education and monitoring resources; service culture, including an interdisciplinary clinic goal; and knowledge sharing from expert dietitians. Barriers included perceived challenges for patients from diverse cultural and socioeconomic backgrounds; and limited clinician training, time and resourcing to support behaviour change. Integration of MDP in routine management of NAFLD in specialist clinics was facilitated by a focus on diet quality, knowledge sharing, belief in evidence and an interdisciplinary team. Innovations to service delivery could better support and empower patients to change dietary behaviour long-term.

scholarly journals Dietary patterns and risk of non-alcoholic fatty liver disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ammar Salehi-sahlabadi ◽  
Samaneh Sadat ◽  
Sara Beigrezaei ◽  
Makan Pourmasomi ◽  
Awat Feizi ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Western Dietary Pattern ◽  
Crude Model ◽  
Alcoholic Fatty Liver Disease ◽  
Healthy Dietary Pattern

Abstract Background Nutrition is a modifiable risk factor that plays an important role in the prevention or delaying of the onset of non-alcoholic fatty liver disease (NAFLD). Previous studies have focused on NAFLD and individual nutrients, which does not take into account combinations of food that are consumed. Therefore, we aimed to investigate the relationship between major dietary patterns and NAFLD. Methods This case–control study was conducted on 225 newly diagnosed NAFLD patients and 450 healthy controls. Usual dietary intake over the preceding year was assessed using a validated 168-item semi-quantitative food frequency questionnaire. Major dietary patterns were determined by exploratory factor analysis. Results Three dietary patterns, including "western dietary pattern", "healthy dietary pattern", and "traditional dietary pattern" were identified. Subjects in the highest tertile of healthy dietary pattern scores had a lower odds ratio for NAFLD than those in the lowest tertile. Compared with those in the lowest tertile, people in the highest tertile of “western dietary pattern” scores had greater odds for NAFLD. After adjusting for potential confounding factors, “western dietary pattern” had a positive significant effect on NAFLD occurrence. In contrast, “healthy dietary pattern” was associated with a decreased risk of NAFLD. Furthermore, Higher consumption of the “traditional dietary pattern” was significantly associated with NAFLD, albeit in the crude model only. Conclusion This study indicated that healthy and western dietary patterns may be associated with the risk of NAFLD. The results can be used for developing interventions in order to promote healthy eating for the prevention of NAFLD.

scholarly journals The Significance of the Mediterranean Diet in the Management of Non-Alcoholic Fatty Liver Disease: A Systematic Review

Cureus ◽  
2021 ◽  
Author(s):  
Harpreet Gosal ◽  
Harsimran Kaur ◽  
Hyginus Chakwop Ngassa ◽  
Khaled A Elmenawi ◽  
Vishwanath Anil ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Disease ◽  
Fatty Liver ◽  
Mediterranean Diet ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
The Mediterranean ◽  
Alcoholic Fatty Liver Disease

scholarly journals Liver and Nutrition. An Optimal Diet for Non-Alcoholic Fatty Liver Disease

2018 ◽  
Vol 28 (5) ◽  
pp. 105-116 ◽  
Author(s):  
M. V. Mayevskaya ◽  
V. T. Ivashkin
Keyword(s):  
Fatty Acids ◽  
Liver Disease ◽  
Fatty Liver ◽  
Mediterranean Diet ◽  
Fatty Liver Disease ◽  
Metabolic Disorders ◽  
Omega 3 ◽  
Alcoholic Fatty Liver ◽  
The Mediterranean ◽  
Alcoholic Fatty Liver Disease

Aim. This review study is aimed at characterizing the nutrition of patients with non-alcoholic fatty liver disease (NAFLD).General findings.A high-calorie diet, followed even for a short period of time, can lead to an increase in the lipid content in hepatocytes and an increase in ALT values. These changes occur much earlier than weight gain, glucose metabolism disorders and other clinically obvious changes. So far, only the Mediterranean diet (or the Mediterranean type of food) has been scientifically confirmed as beneficial for human health. It is recommended for patients with NAFLD both by Russian and international clinical guidelines. The molecular mechanisms of beneficial effects on human health have been confirmed for such Mediterranean diet components as polyphenols, carotenoids, oleic acid, polyunsaturated fatty acids and dietary fiber. The enrichment of the Mediterranean diet with olive oil (+10 g) reduces the risk of diabetes mellitus by 40 %. The addition of Omega-3 fatty acids to food reduces the risk of hepatocellular cancer. A balanced ratio of omega 3 and omega 6 in the diet is more important than the absolute amount of individual fatty acids. Vegetables and fruit contain two main classes of antioxidants: polyphenols and carotenoids. In patients with NAFLD, they exhibit an anti-inflammatory and antifibrotic effect both in vivo and in vitro. Food produced from whole grain has a lower energy potential as compared to that produced from refined grain. Meat contains various nutrients, such as proteins, iron, zinc, B12 vitamin, as well as sodium, saturated fatty acids and cholesterol, which serve as risk factors for the development of NAFLD and other cardio-metabolic disorders. In this paper, we present a clinical observation of a 51-year-old patient with NAFLD and cardio-metabolic disorders. Practical recommendations are given on changes in his lifestyle and the choice of optimal therapy with the application of multifunctional drugs affecting all disease aspects.Conclusion.The concepts of ‘correct or healthy’ nutrition and ‘lifestyle modification’ are increasingly attracting much attention both in terms of the prevention and treatment of liver diseases. Proper nutrition is important for a good life prognosis in patients with non-alcoholic fatty liver disease (NAFLD). 

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