scholarly journals Radiotherapeutic strategies for hepatocellular carcinoma with portal vein tumour thrombosis in a hepatitis B endemic area

2016 ◽  
Vol 37 (1) ◽  
pp. 90-100 ◽  
Author(s):  
Jung Ho Im ◽  
Sang Min Yoon ◽  
Hee Chul Park ◽  
Jong Hoon Kim ◽  
Jeong Il Yu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B ◽  
Portal Vein ◽  
Endemic Area

Clinical features of HBsAg-negative but anti-HBc-positive hepatocellular carcinoma in a hepatitis B virus endemic area

2005 ◽  
Vol 20 (5) ◽  
pp. 746-751 ◽  
Author(s):  
JAEJUN SHIM ◽  
BYUNG-HO KIM ◽  
NAM HOON KIM ◽  
SEOK HO DONG ◽  
HYO JONG KIM ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Clinical Features ◽  
Endemic Area ◽  
B Virus

scholarly journals Effects of Positive Hepatitis B Core Antibody and Metabolic Disorders in Hepatocellular Carcinoma in an Endemic Area of Hepatitis B Virus

2021 ◽  
Vol 28 ◽  
pp. 107327482110397
Author(s):  
Hae Lim Lee ◽  
Si Hyun Bae ◽  
Jaejun Lee ◽  
Pil Soo Sung ◽  
Sung Won Lee ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B ◽  
Liver Function ◽  
Clinical Characteristics ◽  
Endemic Area ◽  
Metabolic Disorders ◽  
Advanced Tumor Stage ◽  
Advanced Tumor ◽  
Significant Difference ◽  
The Impact

Background and Aims This retrospective study aimed to investigate the impact of positive hepatitis B core antibody (anti-HBc) and metabolic disorders on clinical characteristics of hepatocellular carcinoma (HCC) patients in an HBV-endemic area. Methods A total of 1950 consecutive patients newly diagnosed with HCC between 2002 and 2015 were included. Patient records were reviewed. We compared non-viral and non-alcoholic HCC patients with other etiological groups for HCC. In addition, we compared HCC patients with negative hepatitis B surface antigen (HBsAg) and positive anti-HBc to those with negative HBsAg and negative anti-HBc, and to those with HBV. Results The prevalence of non-viral and non-alcoholic HCC increased from 7% in 2002–2011 to 12% in 2012–2015. The proportion of non-viral and non-alcoholic HCC gradually increased with age. Patients with non-viral and non-alcoholic HCC exhibited higher rates of metabolic disorders and preserved liver function. The rate of anti-HBc positivity was similarly high in all HCC etiological groups. The clinical features of HCC patients with negative HBsAg and positive anti-HBc were similar to those with negative HBsAg and negative anti-HBc, but significantly different from those with HBV HCC. Regarding tumor characteristics, patients in the non-viral and non-alcoholic HCC group had more advanced stages of tumors (mUICC stage III–V and BCLC stage C/D). There was no significant difference in overall survival among the patient groups. The presence of anti-HBc did not affect patient survival. Conclusion Patients with non-viral and non-alcoholic HCC had a relatively high prevalence of metabolic disorders and preserved liver function. However, they had advanced tumor stage compared to patients from other etiological groups. Anti-HBc positivity did not affect the clinical characteristics or prognosis of non-HBV HCC patients in this study.

Liver Resection for Hepatocellular Carcinoma in a Hepatitis B Endemic Area

2007 ◽  
Vol 31 (9) ◽  
pp. 1775-1781 ◽  
Author(s):  
Adam St. J. R. Bartlett ◽  
John L. McCall ◽  
Jonathan B. Koea ◽  
Andrew Holden ◽  
Mee-Ling Yeong ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Resection ◽  
Hepatitis B ◽  
Endemic Area
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