Elevated serum ferritin is associated with increased mortality in non-alcoholic fatty liver disease after 16 years of follow-up

2016 ◽  
Vol 36 (11) ◽  
pp. 1688-1695 ◽  
Author(s):  
Hannes Hagström ◽  
Patrik Nasr ◽  
Matteo Bottai ◽  
Mattias Ekstedt ◽  
Stergios Kechagias ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Serum Ferritin ◽  
Fatty Liver Disease ◽  
Elevated Serum ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals Non-resolution of non-alcoholic fatty liver disease (NAFLD) among urban, adult Sri Lankans in the general population: A prospective, cohort follow-up study

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0224474
Author(s):  
Madunil Anuk Niriella ◽  
Anuradhani Kasturiratna ◽  
Thulani Beddage ◽  
Dileepa Senajith Ediriweera ◽  
Shamila Thivanshi De Silva ◽  
...  
Keyword(s):  
Liver Disease ◽  
General Population ◽  
Fatty Liver ◽  
Prospective Cohort ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Follow Up Study ◽  
Alcoholic Fatty Liver Disease

Serum ferritin levels predict incident non-alcoholic fatty liver disease in healthy Korean men

Metabolism ◽  
2012 ◽  
Vol 61 (8) ◽  
pp. 1182-1188 ◽  
Author(s):  
Chan-Won Kim ◽  
Yoosoo Chang ◽  
Eunju Sung ◽  
Hocheol Shin ◽  
Seungho Ryu
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Serum Ferritin ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals Remnant Lipoprotein Cholesterol and Cardiovascular and Cerebrovascular Events in Patients with Non-Alcoholic Fatty Liver Disease

2018 ◽  
Vol 7 (11) ◽  
pp. 378 ◽  
Author(s):  
Daniele Pastori ◽  
Francesco Baratta ◽  
Marta Novo ◽  
Nicholas Cocomello ◽  
Francesco Violi ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Density Lipoprotein ◽  
Alcoholic Fatty Liver ◽  
Remnant Lipoprotein ◽  
Cerebrovascular Events ◽  
Alcoholic Fatty Liver Disease

: Non-alcoholic fatty liver disease (NAFLD) is characterized by an atherogenic dyslipidaemia and an increased cardiovascular risk. Remnant lipoprotein cholesterol (RLP-C) is emerging as a novel cardiovascular risk factor, but its predictive value in patients with NAFLD is unknown. We investigated factors affecting RLP-C levels, and the association with major adverse cardiovascular and cerebrovascular events (MACCE) in NAFLD. A prospective observational cohort study was carried out including 798 unselected patients with cardio-metabolic diseases screened by ultrasound for the presence of NAFLD. Fasting RLP-C (mg/dL) was calculated as total cholesterol—(HDL (high-density lipoprotein) + LDL (low-density-lipoprotein)). Primary endpoint of the follow-up study was a combined endpoint of MACCE. Patients with NAFLD (79.2%) had higher median fasting RLP-C in comparison to those without (27.0 vs. 20.0 mg/ dL, respectively p < 0.001). Metabolic syndrome, NAFLD, age above median, and female sex were independently associated to fasting RLP-C above the median. In patients with NAFLD, values of RLP-C were associated with liver disease severity, as shown by the increasing value of RLP-C across tertiles of aspartate aminotransferase (AST) (p = 0.002) and gamma-glutamyl transpeptidase (GGT) (p < 0.001). Furthermore, levels of RLP-C and Hamaguchi score, were significantly correlated (r = 0.193, p < 0.001). During a median follow-up of 32 months (interquartile range: 14.2–51.7, 1700 person-years), 41 MACCE (2.41%/year) were registered in 596 NAFLD patients. The rate of events was higher in NAFLD patients with RLP-C above the median compared to those below (log-rank test p = 0.040). Age (hazard ratio (HR) 1.039, 95% confidence interval (CI), 1.005–1.074, p = 0.024), previous cardiovascular events (HR 2.210, 95% CI, 1.052–4.643, p = 0.036), female sex (HR 0.454, 95% CI, 0.208–0.989, p = 0.047) and RLP-C above the median (HR 2.202, 95% CI, 1.132–4.285, p = 0.020) were associated with MACCE. In conclusion, we found that NAFLD was independently associated with higher circulating RLP-C, and that high RLP-C levels were predictive of MACCE in patients with NAFLD.

A mobile application for the management and follow-up of patients with Non-Alcoholic Fatty Liver Disease

2018 ◽  
Vol 68 ◽  
pp. S819
Author(s):  
R. Forlano ◽  
B.H. Mullish ◽  
N. Katertsidis ◽  
N. Giannakeas ◽  
A. Tzallas ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Mobile Application ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Impact of Weight Regain on the Evolution of Non-alcoholic Fatty Liver Disease After Roux-en-Y Gastric Bypass: a 3-Year Follow-up

2018 ◽  
Vol 28 (10) ◽  
pp. 3131-3135 ◽  
Author(s):  
Laísa Simakawa Jimenez ◽  
Fábio Henrique Mendonça Chaim ◽  
Felipe David Mendonça Chaim ◽  
Murillo Pimentel Utrini ◽  
Martinho Antonio Gestic ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Weight Regain ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease
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