Overall safety profile of boceprevir plus peginterferon alfa-2b and ribavirin in patients with chronic hepatitis C genotype 1: a combined analysis of 3 phase 2/3 clinical trials

Michael P. Manns; Jonathan McCone; Mitchell N. Davis; Lorenzo Rossaro; Eugene Schiff; Mitchel L. Shiffman; Bruce Bacon; Marc Bourliere; Mark S. Sulkowski; Savino Bruno; Luis Balart; Jean-Pierre Bronowicki; Paul Kwo; Fred Poordad; Franco Felizarta; K. Rajender Reddy; Frans A. Helmond; Heather L. Sings; Lisa D. Pedicone; Margaret Burroughs; Clifford A. Brass; Janice K. Albrecht; John M. Vierling

doi:10.1111/liv.12300

Overall safety profile of boceprevir plus peginterferon alfa-2b and ribavirin in patients with chronic hepatitis C genotype 1: a combined analysis of 3 phase 2/3 clinical trials

Liver International ◽

10.1111/liv.12300 ◽

2013 ◽

Vol 34 (5) ◽

pp. 707-719 ◽

Cited By ~ 12

Author(s):

Michael P. Manns ◽

Jonathan McCone ◽

Mitchell N. Davis ◽

Lorenzo Rossaro ◽

Eugene Schiff ◽

...

Keyword(s):

Clinical Trials ◽

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Safety Profile ◽

Phase 2 ◽

Genotype 1 ◽

Combined Analysis ◽

Peginterferon Alfa

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Faculty Opinions recommendation of Overall safety profile of boceprevir plus peginterferon alfa-2b and ribavirin in patients with chronic hepatitis C genotype 1: a combined analysis of 3 phase 2/3 clinical trials.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718367975.793494877 ◽

2014 ◽

Author(s):

Philip Rosenthal

Keyword(s):

Clinical Trials ◽

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Safety Profile ◽

Phase 2 ◽

Genotype 1 ◽

Combined Analysis ◽

Peginterferon Alfa

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1188 PHASE 2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF NITAZOXANIDE WITH PEGINTERFERON ALFA-2A AND RIBAVIRIN IN NONRESPONDERS (NR) WITH CHRONIC HEPATITIS C GENOTYPE 1: FINAL REPORT

Journal of Hepatology ◽

10.1016/s0168-8278(10)61189-0 ◽

2010 ◽

Vol 52 ◽

pp. S461 ◽

Cited By ~ 3

Author(s):

M.L. Shiffman ◽

A. Ahmed ◽

I.M. Jacobson ◽

R.E. Pruitt ◽

E.B. Keeffe

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Controlled Study ◽

Final Report ◽

Phase 2 ◽

Genotype 1 ◽

Double Blind ◽

Double Blind Placebo ◽

Peginterferon Alfa

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4 HCV SPRINT-1 FINAL RESULTS: SVR 24 FROM A PHASE 2 STUDY OF BOCEPREVIR PLUS PEGINTRON™ (PEGINTERFERON ALFA-2B)/RIBAVIRIN IN TREATMENT- NAIVE SUBJECTS WITH GENOTYPE-1 CHRONIC HEPATITIS C

Journal of Hepatology ◽

10.1016/s0168-8278(09)60006-4 ◽

2009 ◽

Vol 50 ◽

pp. S4 ◽

Cited By ~ 49

Author(s):

P. Kwo ◽

E. Lawitz ◽

J. McCone ◽

E. Schiff ◽

J. Vierling ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Phase 2 ◽

Genotype 1 ◽

Phase 2 Study ◽

Treatment Naïve ◽

Peginterferon Alfa

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Faculty Opinions recommendation of Adherence to assigned dosing regimen and sustained virological response among chronic hepatitis C genotype 1 patients treated with boceprevir plus peginterferon alfa-2b/ribavirin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718013666.793491356 ◽

2014 ◽

Author(s):

Philip Rosenthal

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Sustained Virological Response ◽

Chronic Hepatitis C ◽

Virological Response ◽

Genotype 1 ◽

Dosing Regimen ◽

Peginterferon Alfa

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Boceprevir With Peginterferon Alfa-2a–Ribavirin Is Effective for Previously Treated Chronic Hepatitis C Genotype 1 Infection

Clinical Gastroenterology and Hepatology ◽

10.1016/j.cgh.2012.10.006 ◽

2013 ◽

Vol 11 (1) ◽

pp. 81-87.e4 ◽

Cited By ~ 48

Author(s):

Steven L. Flamm ◽

Eric Lawitz ◽

Ira Jacobson ◽

Marc Bourlière ◽

Christophe Hezode ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Genotype 1 ◽

Previously Treated ◽

Peginterferon Alfa

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Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia

Journal of Hepatology ◽

10.1016/j.jhep.2005.10.003 ◽

2006 ◽

Vol 44 (1) ◽

pp. 97-103 ◽

Cited By ~ 339

Author(s):

Stefan Zeuzem ◽

Maria Buti ◽

Peter Ferenci ◽

Jan Sperl ◽

Yves Horsmans ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Genotype 1 ◽

Peginterferon Alfa

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1163 A PHASE 2A STUDY OF BMS-791325, AN NS5B POLYMERASE INHIBITOR, WITH PEGINTERFERON ALFA-2A AND RIBAVIRIN IN TREATMENT-NAIVE PATIENTS WITH GENOTYPE 1 CHRONIC HEPATITIS C INFECTION

Journal of Hepatology ◽

10.1016/s0168-8278(12)61175-1 ◽

2012 ◽

Vol 56 ◽

pp. S460 ◽

Cited By ~ 4

Author(s):

H. Tatum ◽

P. Thuluvath ◽

E. Lawitz ◽

C.T. Martorell ◽

M. Demicco ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Genotype 1 ◽

Hepatitis C Infection ◽

Ns5b Polymerase Inhibitor ◽

Treatment Naïve ◽

Polymerase Inhibitor ◽

Peginterferon Alfa ◽

Ns5b Polymerase

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Sa1052 Triple Therapy Under Real Life Conditions: Telaprevir (TVR) in Combination With Peginterferon-Alfa-2A Plus Ribavirin (P/R) in NaïVE Patients Infected With Chronic Hepatitis C, Genotype 1. The PAN Study

Gastroenterology ◽

10.1016/s0016-5085(13)63650-1 ◽

2013 ◽

Vol 144 (5) ◽

pp. S-983

Author(s):

Gero Moog ◽

Stefan Mauss ◽

Dietrich Hueppe ◽

Ulrich Spengler ◽

Eckart Schott ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Triple Therapy ◽

Chronic Hepatitis C ◽

Real Life ◽

Genotype 1 ◽

Life Conditions ◽

Peginterferon Alfa

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746 NARLAPREVIR AND PEGINTERFERON ALFA-2B FOR 2 WEEKS IN CHRONIC HEPATITIS C GENOTYPE 1 PATIENTS, FOLLOWED BY PEGINTERFERON ALFA-2B AND RIBAVIRIN FOR 24/48 WEEKS: FINAL RESULTS

Journal of Hepatology ◽

10.1016/s0168-8278(10)60748-9 ◽

2010 ◽

Vol 52 ◽

pp. S290-S291 ◽

Cited By ~ 2

Author(s):

J. de Bruijne ◽

J.F. Bergmann ◽

C.J. Weegink ◽

R. Molenkamp ◽

J. Schinkel ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Genotype 1 ◽

Peginterferon Alfa

Download Full-text

Sa1041 Triple Therapy Under Real Life Conditions: Telaprevir (TVR) and Boceprevir (BOC) in Combination With Peginterferon-Alfa-2A Plus Ribavirin (P/R) in Treatment Experienced Patients Infected With Chronic Hepatitis C, Genotype 1. the PAN Study

Gastroenterology ◽

10.1016/s0016-5085(13)63639-2 ◽

2013 ◽

Vol 144 (5) ◽

pp. S-980 ◽

Cited By ~ 1

Author(s):

Gero Moog ◽

Stefan Mauss ◽

Dietrich Hueppe ◽

Ulrich Spengler ◽

Eckart Schott ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C ◽

Triple Therapy ◽

Chronic Hepatitis C ◽

Real Life ◽

Genotype 1 ◽

Life Conditions ◽

Peginterferon Alfa

Download Full-text