Liver stiffness measurement as an alternative to fibrotic stage in risk assessment of hepatocellular carcinoma incidence for chronic hepatitis C patients

2013 ◽  
Vol 33 (5) ◽  
pp. 756-761 ◽  
Author(s):  
Hsin-Ming Wang ◽  
Chao-Hung Hung ◽  
Sheng-Nan Lu ◽  
Chien-Hung Chen ◽  
Chuan-Mo Lee ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Risk Assessment ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Chronic Hepatitis C Patients

M1570 Prospective Comparison of Liver Stiffness Measurement and Lok Index in Chronic Hepatitis C Patients

2008 ◽  
Vol 134 (4) ◽  
pp. A-795
Author(s):  
Ryota Masuzaki ◽  
Ryosuke Tateishi ◽  
Haruhiko Yoshida ◽  
Eriko Goto ◽  
Takahisa Sato ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Prospective Comparison ◽  
Chronic Hepatitis C Patients

scholarly journals Liver stiffness measurement and spleen diameter as predictors for the presence of esophageal varices in chronic hepatitis C patients

Medicine ◽  
2017 ◽  
Vol 96 (46) ◽  
pp. e8621 ◽  
Author(s):  
Mohammed Tag-Adeen ◽  
Mohamed Alsenbesy ◽  
Ali Abdelrahman Ghweil ◽  
M. Ali Hussein Abd Elrazek ◽  
Elsayed A. Elgohary ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Esophageal Varices ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Chronic Hepatitis C Patients

scholarly journals Liver stiffness measurement predicts liver-related events in patients with chronic hepatitis C: A retrospective study

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0184404 ◽  
Author(s):  
Ana Zaida Gomez-Moreno ◽  
Daniel Pineda-Tenor ◽  
Maria Angeles Jimenez-Sousa ◽  
Juan Jose Sánchez-Ruano ◽  
Tomas Artaza-Varasa ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Retrospective Study ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement

Accuracy of the ElastPQ® Technique for the Assessment of Liver Fibrosis in Patients with Chronic Hepatitis C: a “Real Life” Single Center Study

2016 ◽  
Vol 25 (3) ◽  
pp. 331-335 ◽  
Author(s):  
Giovanna Ferraioli ◽  
Laura Maiocchi ◽  
Raffaella Lissandrin ◽  
Carmine Tinelli ◽  
Annalisa De Silvestri ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Liver Fibrosis ◽  
Chronic Hepatitis C ◽  
Liver Stiffness ◽  
Real Life ◽  
Advanced Fibrosis ◽  
Liver Stiffness Measurement ◽  
Significant Fibrosis ◽  
Stiffness Measurement

Background & Aims: Noninvasive assessment of liver stiffness has been increasingly used to evaluate fibrosis instead of liver biopsy, especially in patients with chronic viral hepatitis. The aim of this study was to assess the performance in staging liver fibrosis of the updated ElastPQ® technique (EPIQ7 ultrasound system, Philips Healthcare, Bothell, WA, USA) in the “real life” setting by using the FibroScan as the reference standard and to understand whether the use of the quality criteria improves the performance of the technique. Methods: This was a cross-sectional study: 278 patients affected by chronic hepatitis C referred for liver stiffness measurement with the FibroScan® 502 Touch device (Echosens, Paris, France) underwent measurements also with the ElastPQ® technique. For the assessment of significant fibrosis (F≥2), advanced fibrosis (F≥3) and cirrhosis (F=4), respectively, we used the cutoffs of 7.0, 9.5 and 12.0 kPa. The diagnostic performance of ElastPQ® was assessed using the area under the ROC (AUROC) curve analysis and was evaluated overall and for cases with (a) 10 measurements and IQR/M≤30%, (b) 5 measurements and IQR/M ≤30%, (c) 10 measurements and IQR/M>30%, (d) 5 measurements and IQR/M>30%. Results: The optimal cutoffs of ElastPQ® for significant fibrosis, advanced fibrosis and cirrhosis were 6.43, 9.54 and 11.34 kPa, respectively. For measurements with an IQR/M≤30%, there was no statistically significant decrease in sensitivity between 10 and 5 measurements (p=0.26, p=0.09, p=0.71, for F≥2, F≥3, and F=4, respectively). Conclusion: The ElastPQ® technique is reliable and accurate for staging liver fibrosis. The number of measurements does not affect the performance. Abbreviations: ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; AUROC: area under the ROC curve; BMI: body mass index; GGT: gamma-glutamyl transferase; LR: likelihood ratio; LSM: liver stiffness measurement; pSWE: point shear wave elastography; ROC: receiver operating characteristic; VCTE: vibration controlled transient elastography; VTQ®: virtual touch quantification.

Risk Assessment of Hepatocellular Carcinoma in Chronic Hepatitis C Patients by Transient Elastography

2008 ◽  
Vol 42 (7) ◽  
pp. 839-843 ◽  
Author(s):  
Ryota Masuzaki ◽  
Ryosuke Tateishi ◽  
Haruhiko Yoshida ◽  
Hideo Yoshida ◽  
Shinpei Sato ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Risk Assessment ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Transient Elastography ◽  
Chronic Hepatitis C Patients
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