scholarly journals Sequential interactions of silver-silica nanocomposite (Ag-SiO2NC) with cell wall, metabolism and genetic stability ofPseudomonas aeruginosa, a multiple antibiotic-resistant bacterium

2012 ◽  
Vol 56 (1) ◽  
pp. 57-62 ◽  
Author(s):  
A. Anas ◽  
J. Jiya ◽  
M.J. Rameez ◽  
P.B. Anand ◽  
M.R. Anantharaman ◽  
...  
Keyword(s):  
Cell Wall ◽  
Genetic Stability ◽  
Resistant Bacterium ◽  
Cell Wall Metabolism ◽  
Antibiotic Resistant ◽  
Antibiotic Resistant Bacterium ◽  
Silica Nanocomposite

Influence of Dissolved Organic Matter on Tetracycline Bioavailability to an Antibiotic-Resistant Bacterium

2015 ◽  
Vol 49 (18) ◽  
pp. 10903-10910 ◽  
Author(s):  
Zeyou Chen ◽  
Yingjie Zhang ◽  
Yanzheng Gao ◽  
Stephen A. Boyd ◽  
Dongqiang Zhu ◽  
...  
Keyword(s):  
Organic Matter ◽  
Dissolved Organic Matter ◽  
Resistant Bacterium ◽  
Antibiotic Resistant ◽  
Antibiotic Resistant Bacterium

scholarly journals A Metzincin and TIMP-Like Protein Pair of a Phage Origin Sensitize Listeria monocytogenes to Phage Lysins and Other Cell Wall Targeting Agents

2021 ◽  
Vol 9 (6) ◽  
pp. 1323
Author(s):  
Etai Boichis ◽  
Nadejda Sigal ◽  
Ilya Borovok ◽  
Anat A. Herskovits
Keyword(s):  
Cell Wall ◽  
Listeria Monocytogenes ◽  
Mammalian Cells ◽  
Protein Pair ◽  
Growth Conditions ◽  
Wall Structure ◽  
Antibiotic Resistant ◽  
Extracellular Milieu ◽  
Virion Release ◽  
Genes Encoding

Infection of mammalian cells by Listeria monocytogenes (Lm) was shown to be facilitated by its phage elements. In a search for additional phage remnants that play a role in Lm’s lifecycle, we identified a conserved locus containing two XRE regulators and a pair of genes encoding a secreted metzincin protease and a lipoprotein structurally similar to a TIMP-family metzincin inhibitor. We found that the XRE regulators act as a classic CI/Cro regulatory switch that regulates the expression of the metzincin and TIMP-like genes under intracellular growth conditions. We established that when these genes are expressed, their products alter Lm morphology and increase its sensitivity to phage mediated lysis, thereby enhancing virion release. Expression of these proteins also sensitized the bacteria to cell wall targeting compounds, implying that they modulate the cell wall structure. Our data indicate that these effects are mediated by the cleavage of the TIMP-like protein by the metzincin, and its subsequent release to the extracellular milieu. While the importance of this locus to Lm pathogenicity remains unclear, the observation that this phage-associated protein pair act upon the bacterial cell wall may hold promise in the field of antibiotic potentiation to combat antibiotic resistant bacterial pathogens.

Cell wall metabolism during durian fruit dehiscence

2008 ◽  
Vol 48 (3) ◽  
pp. 391-401 ◽  
Author(s):  
L. Khurnpoon ◽  
J. Siriphanich ◽  
J.M. Labavitch
Keyword(s):  
Cell Wall ◽  
Cell Wall Metabolism ◽  
Fruit Dehiscence
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