Pharmacokinetic profiles of amoxicillin trihydrate in freshwater crocodiles ( Crocodylus siamensis ) after intramuscular administration at two doses

2020 ◽  
Vol 43 (4) ◽  
pp. 307-312 ◽  
Author(s):  
Saranya Poapolathep ◽  
Mario Giorgi ◽  
Narumol Klangkaew ◽  
Napasorn Phaochoosak ◽  
Narongsak Chaiyabutr ◽  
...  
Keyword(s):  
Intramuscular Administration ◽  
Pharmacokinetic Profiles ◽  
Amoxicillin Trihydrate ◽  
Crocodylus Siamensis

Pharmacokinetics of marbofloxacin in freshwater crocodiles (Crocodylus siamensis) after intravenous and intramuscular administration

2016 ◽  
Vol 40 (1) ◽  
pp. 57-61 ◽  
Author(s):  
S. Poapolathep ◽  
M. Giorgi ◽  
S. Hantrakul ◽  
N. Klangkaew ◽  
P. Sanyathitiseree ◽  
...  
Keyword(s):  
Intramuscular Administration ◽  
Crocodylus Siamensis

Pharmacokinetics of ceftriaxone in freshwater crocodiles ( Crocodylus siamensis ) after intramuscular administration at two dosages

2020 ◽  
Vol 43 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Saranya Poapolathep ◽  
Mario Giorgi ◽  
Narongsak Chaiyabutr ◽  
Narumol Klangkaew ◽  
Napasorn Phaochoosak ◽  
...  
Keyword(s):  
Intramuscular Administration ◽  
Crocodylus Siamensis

Pharmacokinetics of amoxicillin trihydrate in male Asian elephants (Elephas maximus ) following intramuscular administration

2015 ◽  
Vol 39 (3) ◽  
pp. 287-291 ◽  
Author(s):  
P. Sinphithakkul ◽  
N. Klangkaew ◽  
P. Sanyathitiseree ◽  
M. Giorgi ◽  
S. Kumagai ◽  
...  
Keyword(s):  
Elephas Maximus ◽  
Intramuscular Administration ◽  
Asian Elephants ◽  
Amoxicillin Trihydrate

Pharmacokinetic profiles of clarithromycin in freshwater crocodiles ( Crocodylus siamensis )

2021 ◽  
Author(s):  
Saranya Poapolathep ◽  
Mario Giorgi ◽  
Narumol Klangkaew ◽  
Kraisiri Khidkhan ◽  
Narongsak Chaiyabutr ◽  
...  
Keyword(s):  
Pharmacokinetic Profiles ◽  
Crocodylus Siamensis

Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in freshwater crocodiles (Crocodylus siamensis) after intravenous and intramuscular administration

2019 ◽  
Vol 43 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Saranya Poapolathep ◽  
Mario Giorgi ◽  
Narongsak Chaiyabutr ◽  
Chanat Chokejaroenrat ◽  
Narumol Klangkaew ◽  
...  
Keyword(s):  
Intramuscular Administration ◽  
Crocodylus Siamensis

scholarly journals Comparative Pharmacokinetics of Ceftaroline in Rats, Rabbits, and Monkeys following a Single Intravenous or Intramuscular Injection

2009 ◽  
Vol 54 (2) ◽  
pp. 912-914 ◽  
Author(s):  
Yigong Ge ◽  
David Maynard ◽  
Douglas E. Rickert
Keyword(s):  
Intramuscular Injection ◽  
Animal Species ◽  
Intramuscular Administration ◽  
Time Curve ◽  
Gram Negative ◽  
Pharmacokinetic Profiles ◽  
Concentration Time ◽  
Spectrum Activity ◽  
Plasma Concentration Time Curve ◽  
Broad Spectrum Activity

ABSTRACT This study assessed the pharmacokinetic profiles for intramuscular and intravenous ceftaroline treatment for rats, rabbits, and monkeys. Ceftaroline, a novel cephalosporin with broad-spectrum activity against Gram-positive and Gram-negative pathogens, demonstrated favorable pharmacokinetic profiles following intramuscular administration in all 3 animal species, comparable to the levels for intravenous dosing. The areas under the plasma concentration-time curve obtained after intramuscular administration were increased in rats and similar in rabbits and monkeys, compared with the levels obtained after intravenous dosing (129%, 7.29%, and 12.7% greater in rats, rabbits, and monkeys, respectively). The data reported here support the development of an intramuscular formulation for ceftaroline.

TRANSFORMATION OF Δ5-ANDROSTENE-3,17-DIONE TO A Δ5-3α-HYDROXYSTEROID IN MAN

1962 ◽  
Vol 41 (3) ◽  
pp. 391-394 ◽  
Author(s):  
David K. Fukushima ◽  
Kenneth I. H. Williams ◽  
Barnett Zumoff ◽  
T. F. Gallagher
Keyword(s):  
Intramuscular Administration ◽  
No Conversion

ABSTRACT 3α-Hydroxy-Δ5-androsten-17-one has been isolated following intramuscular administration of Δ5-androstene-3,17-dione to man. There was very little or no conversion to 3β-hydroxy-Δ5 epimer. Significant amounts of androsterone and aetiocholanolone were obtained.

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