scholarly journals A dosing algorithm for individualized radioiodine treatment of cats with hyperthyroidism

2021 ◽  
Author(s):  
Mark E. Peterson ◽  
Mark Rishniw
Keyword(s):  
Radioiodine Treatment ◽  
Dosing Algorithm

Radioiodine treatment of feline hyperthyroidism in Germany

2002 ◽  
Vol 41 (06) ◽  
pp. 245-251 ◽  
Author(s):  
M. Knietsch ◽  
T. Spillmann ◽  
E.-G. Grünbaum ◽  
R. Bauer ◽  
M. Puille
Keyword(s):  
Radiation Exposure ◽  
Radiation Protection ◽  
Thyroid Function ◽  
Radioiodine Therapy ◽  
Whole Body ◽  
Radioiodine Treatment ◽  
Normal Thyroid ◽  
Normal Thyroid Function ◽  
Body Activity ◽  
Thyroid Uptake

SummaryAim: Establishment of radioiodine treatment of feline hyperthyroidism in veterinary routine in accordance with German radiation protection regulations. Patients and methods: 35 cats with proven hyperthyroidism were treated with 131I in a special ward. Thyroid uptake and effective halflife were determined using gammacamera dosimetry. Patients were released when measured whole body activity was below the limit defined in the German “Strahlenschutzverordnung”. Results: 17/20 cats treated with 150 MBq radioiodine and 15/15 cats treated with 250 MBq had normal thyroid function after therapy, normal values for FT3 and FT4 were reached after two and normal TSH levels after three weeks. In 14 cats normal thyroid function was confirmed by controls 3-6 months later. Thyroidal iodine uptake was 24 ± 10%, effective halflife 2.5 ± 0.7 days. Whole body activity <1 MBq was reached 13 ± 4 days after application of 131I. Radiation exposure of cat owners was estimated as 1.97 Sv/MBq for adults. Conclusion: Radioiodine therapy of feline hyper-thyroidism is highly effective and safe. It can easily be performed in accordance with German radiation protection regulations, although this requires hospitalisation for approximately two weeks. Practical considerations on radiation exposure of cat owners do not justify this long interval. Regulations for the veterinary use of radioactive substances similar to existing regulations for medical use in humans are higly desirable.

Evaluation of the effectiveness of personalized radioiodine treatment in Graves' disease

2017 ◽  
Author(s):  
Ana Fernandes ◽  
Teresa Faria ◽  
Ana Oliveira ◽  
Jorge Pereira ◽  
Pedro Coelho
Keyword(s):  
Graves Disease ◽  
Radioiodine Treatment

Assessment of radioiodine treatment for hyperthyroidism

2018 ◽  
Author(s):  
Feleh Emna El ◽  
Sana Mahjoubi ◽  
Ali Sellem ◽  
Haroun Ouertani
Keyword(s):  
Radioiodine Treatment

Effectiveness of radioiodine treatment for toxic adenoma

2018 ◽  
Author(s):  
Osorio Ana Sofia ◽  
Martins Ana Filipa ◽  
de Castro Raquel Vaz ◽  
Vania Gomes ◽  
Carolina Faria ◽  
...  
Keyword(s):  
Radioiodine Treatment ◽  
Toxic Adenoma

Long-term follow-up of differentiated thyroid carcinoma in children and adolescents

2020 ◽  
Vol 33 (11) ◽  
pp. 1431-1441
Author(s):  
Montserrat Negre Busó ◽  
Amparo García Burillo ◽  
Marc Simó Perdigó ◽  
Pere Galofré Mora ◽  
Maria Boronat de Ferrater ◽  
...  
Keyword(s):  
Complete Remission ◽  
Thyroid Carcinoma ◽  
Children And Adolescents ◽  
Differentiated Thyroid Carcinoma ◽  
Radioiodine Treatment ◽  
Persistent Disease ◽  
Stage 4 ◽  
Long Term Follow Up

AbstractObjectivesThe aims were to analyze the clinical features, response to treatment, prognostic factors and long-term follow-up of children and adolescents with differentiated thyroid carcinoma (DTC).MethodsEighty patients with DTC were studied retrospectively. All underwent total or near-total thyroidectomy, and in 75 cases, ablative iodine therapy was recommended. Patients were assessed periodically by tests for serum thyroglobulin levels and whole-body iodine scans. Age, gender, initial clinical presentation, histology, tumor stage, postoperative complications, radioiodine treatment protocol, treatment response, thyroglobulin (Tg), recurrence and long-term disease progression were evaluated.ResultsSeventy patients completed >2 years of follow-up (23 males, 47 females; median age: 14 years; range: 3–18 years). Sixty-two patients showed papillary DTC and eight, follicular DTC. Sixty-five percent presented nodal metastasis and 16%, pulmonary metastasis at diagnosis. Six months after first radioiodine treatment, 36.2% of patients were free of disease. Seven recurrences were documented. At the end of follow-up, overall survival was 100%, and 87.2% of patients were in complete remission. Nine patients had persistent disease. We found a significant association between stage 4 and persistent disease. Hundred percent of patients with negative Tg values at 6 months posttreatment were documented free of disease at the end of the follow-up. The analysis of disease-free survival based on radioiodine treatment protocols used showed no statistically significant differences.ConclusionsDTC in children and adolescents is frequently associated with presence of advanced disease at diagnosis. Despite this, complete remission was documented after treatment in most cases, with a good prognosis in the long-term follow-up. Negative posttreatment thyroglobulin and stage 4 at diagnosis were significant prognostic variables.

scholarly journals The Effect of Radioiodine Treatment on TRAb, Anti-TPO, and Anti-TG in Graves’ Disease

2019 ◽  
Vol 8 (2) ◽  
pp. 64-69 ◽  
Author(s):  
Ola Lindgren ◽  
Pernilla Asp ◽  
Anna Sundlöv ◽  
Jan Tennvall ◽  
Bushra Shahida ◽  
...  
Keyword(s):  
Graves Disease ◽  
Radioiodine Treatment

scholarly journals Disappearance rate of endogenously radioiodinated thyroglobulin and thyroxine after radioiodine treatment

Cancer ◽  
1982 ◽  
Vol 49 (11) ◽  
pp. 2281-2284 ◽  
Author(s):  
R. K. Jeevanram ◽  
D. H. Shah ◽  
S. M. Sharma ◽  
R. D. Ganatra
Keyword(s):  
Disappearance Rate ◽  
Radioiodine Treatment
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