scholarly journals Effects of a Sustained-Release Form of Isosorbide Dinitrate on Left Atrial Pressure in Dogs with Experimentally Induced Mitral Valve Regurgitation

2013 ◽  
Vol 27 (6) ◽  
pp. 1421-1426 ◽  
Author(s):  
Y. Yamamoto ◽  
S. Suzuki ◽  
L. Hamabe ◽  
D. Aytemiz ◽  
H. Huai-Che ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Sustained Release ◽  
Isosorbide Dinitrate ◽  
Left Atrial ◽  
Mitral Valve Regurgitation ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Regurgitation ◽  
Sustained Release Form ◽  
Release Form

scholarly journals The Effect of Furosemide on Left Atrial Pressure in Dogs with Mitral Valve Regurgitation

2011 ◽  
Vol 25 (2) ◽  
pp. 244-250 ◽  
Author(s):  
S. Suzuki ◽  
T. Ishikawa ◽  
L. Hamabe ◽  
D. Aytemiz ◽  
H. Huai-Che ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Left Atrial ◽  
Mitral Valve Regurgitation ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Regurgitation

Echocardiographic Estimation of Left Atrial Pressure in Beagle Dogs with Experimentally-Induced Mitral Valve Regurgitation

2011 ◽  
Vol 73 (8) ◽  
pp. 1015-1024 ◽  
Author(s):  
Taisuke ISHIKAWA ◽  
Ryuji FUKUSHIMA ◽  
Shuji SUZUKI ◽  
Yuka MIYAISHI ◽  
Taiki NISHIMURA ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Left Atrial ◽  
Mitral Valve Regurgitation ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Regurgitation ◽  
Beagle Dogs ◽  
Experimentally Induced

scholarly journals Daily Rhythms of Left Atrial Pressure in Beagle Dogs with Mitral Valve Regurgitation

2009 ◽  
Vol 23 (4) ◽  
pp. 824-831 ◽  
Author(s):  
T. Ishikawa ◽  
R. Tanaka ◽  
S. Suzuki ◽  
Y. Saida ◽  
A. Soda ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Left Atrial ◽  
Mitral Valve Regurgitation ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Regurgitation ◽  
Beagle Dogs ◽  
Daily Rhythms

The Effect of Pimobendan on Left Atrial Pressure in Dogs with Mitral Valve Regurgitation

2011 ◽  
Vol 25 (6) ◽  
pp. 1328-1333 ◽  
Author(s):  
S. Suzuki ◽  
R. Fukushima ◽  
T. Ishikawa ◽  
L. Hamabe ◽  
D. Aytemiz ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Left Atrial ◽  
Mitral Valve Regurgitation ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Regurgitation

Characteristics and outcomes of patients with normal left atrial pressure undergoing transcatheter mitral valve repair

Heart ◽  
2020 ◽  
Vol 106 (12) ◽  
pp. 898-903 ◽  
Author(s):  
Jason R Sims ◽  
Guy S Reeder ◽  
Mayra Guerrero ◽  
Mohamad Alkhouli ◽  
Vuyisile T Nkomo ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Left Atrial ◽  
Multivariable Analysis ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Valve Repair ◽  
Transcatheter Mitral Valve Repair ◽  
V Wave ◽  
Regurgitant Orifice Area

ObjectiveA subset of patients at the time of transcatheter mitral valve repair (TMVR) will have normal left atrial pressure (LAP) (<13 mm Hg) despite having severe mitral regurgitation (MR). The goal of this study was to determine clinical characteristics and outcomes in patients with normal LAP undergoing TMVR.MethodsA single-centre retrospective cohort of consecutive patients who underwent transcatheter edge-to-edge mitral valve clip and continuous LAP monitoring between 5/1/2014 and 5/1/2018 was analysed. One-year mortality was compared by Kaplan–Meier survival curves. Multivariable analysis was performed to identify predictors of normal LAP and 1 year mortality.ResultsOf the 204 patients undergoing TMVR, 65% were men and the mean age was 81. Of these patients, 31 (15%) had normal LAP (mean LAP 10.5 mm Hg, mean V wave 16.5 mm Hg) and 173 had elevated LAP (mean LAP 19 mm Hg, mean V wave 32.5 mm Hg). The prevalence of severe MR was not different between groups, although the normal LAP group had significantly lower effective regurgitant orifice area and regurgitant volume. Other notable baseline characteristics including prior cardiac surgery, atrial fibrillation, hypertension, diabetes, congestive heart failure, body mass index, mechanism of MR and ejection fraction were similar between groups. However, there was an increased prevalence of chronic lung disease (CLD) (45.2% vs 17.3%, p<0.001) in the normal LAP group. On multivariate analysis, the only significant predictor of normal LAP was the presence of CLD (OR 4.79 (1.83–12.36), p=0.001) and 1-year mortality was significantly higher in the normal LAP group (32.3% vs 12.7%, p=0.006). After adjustment for comorbidities, normal LAP was no longer a predictor of 1-year mortality (RR 1.62 (0.64–4.06), p=0.32); however, CLD (RR 3.44 (1.37–8.67), p=0.01) remained a statistically significant predictor.ConclusionNormal LAP at the time of TMVR is associated with a higher incidence of CLD which independently predicts increased 1-year mortality. In patients with CLD and apparently severe MR, measurement of LAP may help identify those with lower likelihood of benefit from TMVR.

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