P1-119: Development of the new software pyroedit to quantify editing rate of the hepatitis delta virus RNA: preliminary results on clinical samples

2018 ◽  
Vol 25 ◽  
pp. 86-87
Keyword(s):  
Hepatitis Delta Virus ◽  
Clinical Samples ◽  
Hepatitis Delta ◽  
Preliminary Results ◽  
Virus Rna ◽  
Delta Virus

scholarly journals Analysis of Multiple Liver Explant Pieces Reveals that Levels of Hepatitis Delta Virus RNA Are Independent of Hepatitis B Virus Expression

2021 ◽  
Author(s):  
Kasthuri Prakash ◽  
Simon B. Larsson ◽  
Gustaf E. Rydell ◽  
Johan Ringlander ◽  
Catarina Skoglund ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hepatitis Delta Virus ◽  
Hepatitis Delta ◽  
Virus Rna ◽  
B Virus ◽  
Virus Expression ◽  
Delta Virus

scholarly journals Transcription of Hepatitis Delta Virus RNA by RNA Polymerase II

2007 ◽  
Vol 82 (3) ◽  
pp. 1118-1127 ◽  
Author(s):  
Jinhong Chang ◽  
Xingcao Nie ◽  
Ho Eun Chang ◽  
Ziying Han ◽  
John Taylor
Keyword(s):  
Rna Polymerase ◽  
Rna Polymerase Ii ◽  
Hepatitis Delta Virus ◽  
Cell System ◽  
Hepatitis Delta ◽  
Pol Ii ◽  
Delta Antigen ◽  
Nuclear Extracts ◽  
Virus Rna ◽  
Delta Virus

ABSTRACT Previous studies have indicated that the replication of the RNA genome of hepatitis delta virus (HDV) involves redirection of RNA polymerase II (Pol II), a host enzyme that normally uses DNA as a template. However, there has been some controversy about whether in one part of this HDV RNA transcription, a polymerase other than Pol II is involved. The present study applied a recently described cell system (293-HDV) of tetracycline-inducible HDV RNA replication to provide new data regarding the involvement of host polymerases in HDV transcription. The data generated with a nuclear run-on assay demonstrated that synthesis not only of genomic RNA but also of its complement, the antigenome, could be inhibited by low concentrations of amanitin specific for Pol II transcription. Subsequent studies used immunoprecipitation and rate-zonal sedimentation of nuclear extracts together with double immunostaining of 293-HDV cells, in order to examine the associations between Pol II and HDV RNAs, as well as the small delta antigen, an HDV-encoded protein known to be essential for replication. Findings include evidence that HDV replication is somehow able to direct the available delta antigen to sites in the nucleoplasm, almost exclusively colocalized with Pol II in what others have described as transcription factories.

scholarly journals Self-Cleaving Ribozymes of Hepatitis Delta Virus RNA

1997 ◽  
Vol 247 (3) ◽  
pp. 741-753 ◽  
Author(s):  
Michael D. Been ◽  
Gene S. Wickham
Keyword(s):  
Hepatitis Delta Virus ◽  
Hepatitis Delta ◽  
Virus Rna ◽  
Delta Virus

Hepatitis delta virus RNA, protein synthesis and associated cytotoxicity in a stably transfected cell line

Virology ◽  
1990 ◽  
Vol 177 (2) ◽  
pp. 692-698 ◽  
Author(s):  
T.B. Macnaughton ◽  
E.J. Gowans ◽  
A.R. Albert ◽  
C.J. Burrell
Keyword(s):  
Protein Synthesis ◽  
Cell Line ◽  
Hepatitis Delta Virus ◽  
Hepatitis Delta ◽  
Transfected Cell Line ◽  
Virus Rna ◽  
Delta Virus

scholarly journals Localization of hepatitis delta virus RNA in the nucleus of human cells

RNA ◽  
1998 ◽  
Vol 4 (6) ◽  
pp. 680-693 ◽  
Author(s):  
CELSO CUNHA ◽  
JOÃO MONJARDINO ◽  
DOROTHY CHANG ◽  
SABINE KRAUSE ◽  
MARIA CARMO-FONSECA
Keyword(s):  
Hepatitis Delta Virus ◽  
Human Cells ◽  
Hepatitis Delta ◽  
Virus Rna ◽  
Delta Virus
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