Inverse relationship between hepatic steatosis and hepatitis B viremia: Results of a large case-control study

2017 ◽  
Vol 25 (1) ◽  
pp. 97-104 ◽  
Author(s):  
R. W. H. Hui ◽  
W.-K. Seto ◽  
K.-S. Cheung ◽  
L.-Y. Mak ◽  
K. S. H. Liu ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Hepatic Steatosis ◽  
Inverse Relationship ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Large Case

scholarly journals A large case-control study on the predictability of hepatitis B surface antigen levels three years before hepatitis B surface antigen seroclearance

Hepatology ◽  
2012 ◽  
Vol 56 (3) ◽  
pp. 812-819 ◽  
Author(s):  
Wai-Kay Seto ◽  
Danny Ka-Ho Wong ◽  
James Fung ◽  
Ivan Fan-Ngai Hung ◽  
Daniel Yee-Tak Fong ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Case Control Study ◽  
Hepatitis B Surface Antigen ◽  
Case Control ◽  
Control Study ◽  
Large Case

scholarly journals Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case–control study

2008 ◽  
Vol 89 (11) ◽  
pp. 2882-2890 ◽  
Author(s):  
Zhong-Liao Fang ◽  
Caroline A. Sabin ◽  
Bai-Qing Dong ◽  
Shao-Chao Wei ◽  
Qin-Yan Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Risk Factor ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Case Control Study ◽  
Case Control ◽  
Deletion Mutations ◽  
B Virus ◽  
Nested Case Control ◽  
Control Study

A matched nested case–control study of 33 paired cases and controls was conducted, based on a study cohort in Long An county, Guangxi, China, to determine whether infection with hepatitis B virus (HBV) with pre-S deletions is independently associated with the development of hepatocellular carcinoma (HCC), without the confounding effects of basal core promoter (BCP) double mutations. The prevalence of pre-S deletions was significantly higher in HCC (45.5 %, 15 of 33) than the controls (18.2 %, 6 of 33) (P<0.01), under the control of the influence of BCP double mutations. Most of the pre-S deletions occurred in, or involved, the 5′ half of the pre-S2 region and the difference between HCC (93.3 %, 14 of 15) and controls (66.7 %, four of six) was significant for this region (P=0.015). There was no significant difference in pre-S deletions between the BCP mutant group and BCP wild-type group (P>0.05), nor was the prevalence of pre-S deletions significantly different between genotypes B and C (P>0.1). These results suggest that pre-S deletions constitute an independent risk factor for HCC and their emergence and effect are independent of BCP mutations. The 5′ terminus of pre-S2 is the favoured site for the deletion mutations, especially in HCC cases. Further prospective studies are required to confirm the role of these mutations in the development of HCC.

scholarly journals Dietary N-nitroso compounds and risk of pancreatic cancer: results from a large case–control study

2018 ◽  
Vol 40 (2) ◽  
pp. 254-262 ◽  
Author(s):  
Jiali Zheng ◽  
Janice Stuff ◽  
Hongwei Tang ◽  
Manal M Hassan ◽  
Carrie R Daniel ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Nitroso Compounds ◽  
Control Study ◽  
Large Case

scholarly journals Melanocytic Nevi, Nevus Genes, and Melanoma Risk in a Large Case-Control Study in the United Kingdom

2010 ◽  
Vol 19 (8) ◽  
pp. 2043-2054 ◽  
Author(s):  
Julia A. Newton-Bishop ◽  
Yu-Mei Chang ◽  
Mark M. Iles ◽  
John C. Taylor ◽  
Bert Bakker ◽  
...  
Keyword(s):  
United Kingdom ◽  
Case Control Study ◽  
Case Control ◽  
Melanoma Risk ◽  
Melanocytic Nevi ◽  
The United Kingdom ◽  
Control Study ◽  
Large Case
Sign in / Sign up

Export Citation Format

Share Document