Hospitalizations due to hepatitis C in Los Angeles County, 2007-2009: case characteristics and factors associated with mortality

2013 ◽  
Vol 20 (9) ◽  
pp. 628-637 ◽  
Author(s):  
L. Sie ◽  
N. M. Gatto ◽  
E. Bancroft
Keyword(s):  
Hepatitis C ◽  
Los Angeles ◽  
Los Angeles County ◽  
Factors Associated ◽  
Case Characteristics

scholarly journals Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e043584 ◽  
Author(s):  
Joseph E Ebinger ◽  
Gregory J Botwin ◽  
Christine M Albert ◽  
Mona Alotaibi ◽  
Moshe Arditi ◽  
...  
Keyword(s):  
African American ◽  
Los Angeles ◽  
Delivery System ◽  
Healthcare Workers ◽  
Los Angeles County ◽  
Healthcare Delivery ◽  
Healthcare Delivery System ◽  
Hispanic Ethnicity ◽  
Factors Associated ◽  
African American Race

ObjectiveWe sought to determine the extent of SARS-CoV-2 seroprevalence and the factors associated with seroprevalence across a diverse cohort of healthcare workers.DesignObservational cohort study of healthcare workers, including SARS-CoV-2 serology testing and participant questionnaires.SettingsA multisite healthcare delivery system located in Los Angeles County.ParticipantsA diverse and unselected population of adults (n=6062) employed in a multisite healthcare delivery system located in Los Angeles County, including individuals with direct patient contact and others with non-patient-oriented work functions.Main outcomesUsing Bayesian and multivariate analyses, we estimated seroprevalence and factors associated with seropositivity and antibody levels, including pre-existing demographic and clinical characteristics; potential COVID-19 illness-related exposures; and symptoms consistent with COVID-19 infection.ResultsWe observed a seroprevalence rate of 4.1%, with anosmia as the most prominently associated self-reported symptom (OR 11.04, p<0.001) in addition to fever (OR 2.02, p=0.002) and myalgias (OR 1.65, p=0.035). After adjusting for potential confounders, seroprevalence was also associated with Hispanic ethnicity (OR 1.98, p=0.001) and African-American race (OR 2.02, p=0.027) as well as contact with a COVID-19-diagnosed individual in the household (OR 5.73, p<0.001) or clinical work setting (OR 1.76, p=0.002). Importantly, African-American race and Hispanic ethnicity were associated with antibody positivity even after adjusting for personal COVID-19 diagnosis status, suggesting the contribution of unmeasured structural or societal factors.Conclusion and relevanceThe demographic factors associated with SARS-CoV-2 seroprevalence among our healthcare workers underscore the importance of exposure sources beyond the workplace. The size and diversity of our study population, combined with robust survey and modelling techniques, provide a vibrant picture of the demographic factors, exposures and symptoms that can identify individuals with susceptibility as well as potential to mount an immune response to COVID-19.

scholarly journals Factors Associated with Presence of Pharmacies and Pharmacies that Sell Syringes Over-the-Counter in Los Angeles County

2013 ◽  
Vol 90 (6) ◽  
pp. 1079-1090 ◽  
Author(s):  
Thomas J. Stopka ◽  
Estella M. Geraghty ◽  
Rahman Azari ◽  
Ellen B. Gold ◽  
Kathryn DeRiemer
Keyword(s):  
Los Angeles ◽  
Los Angeles County ◽  
Over The Counter ◽  
Factors Associated

Chronic hepatitis c in ethnic minority patients evaluated in Los Angeles county

2001 ◽  
Vol 96 (8) ◽  
pp. 2438-2441 ◽  
Author(s):  
Maurizio Bonacini ◽  
Susan Groshen ◽  
Mimi C Yu ◽  
Sugantha Govindarajan ◽  
Karen L Lindsay
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Los Angeles ◽  
Ethnic Minority ◽  
Chronic Hepatitis C ◽  
Los Angeles County

scholarly journals Implementation of Targeted Temperature Management After Out‐of‐Hospital Cardiac Arrest: Observations From the Los Angeles County Regional System

2020 ◽  
Vol 9 (24) ◽  
Author(s):  
Melody Hermel ◽  
Nichole Bosson ◽  
Andrea Fang ◽  
William J. French ◽  
James T. Niemann ◽  
...  
Keyword(s):  
Emergency Department ◽  
Cardiac Arrest ◽  
Los Angeles ◽  
Los Angeles County ◽  
The United States ◽  
System Of Care ◽  
Temperature Management ◽  
Factors Associated ◽  
Regional System ◽  
Hospital Cardiac Arrest

Background Despite the benefits of targeted temperature management (TTM) for out‐of‐hospital cardiac arrest), implementation within the United States remains low. The objective of this study was to evaluate the prevalence and factors associated with TTM use in a large, urban‐suburban regional system of care. Methods and Results This was a retrospective analysis from the Los Angeles County regional cardiac system of care serving a population of >10 million residents. All adult patients aged ≥18 years with non‐traumatic out‐of‐hospital cardiac arrest transported to a cardiac arrest center from April 2011 to August 2017 were included. Patients awake and alert in the emergency department and patients who died in the emergency department before consideration for TTM were excluded. The primary outcome measure was prevalence of TTM use. The secondary analysis were annual trends in TTM use over the study period and factors associated with TTM use. The study population included 8072 patients; 4154 patients (51.5%) received TTM and 3767 patients (46.7%) did not receive TTM. Median age was 67 years, 4780 patients (59.2%) were men, 4645 patients (57.5%) were non‐White, and the most common arrest location was personal residence in 4841 patients (60.0%). In the adjusted analysis, younger age, male sex, an initial shockable rhythm, witnessed arrest, and receiving coronary angiography were associated with receiving TTM. Conclusions Within this regional system of care, use of TTM was higher than previously reported in the literature at just over 50%. Use of integrated systems of care may be a novel method to increase TTM use within the United States.

scholarly journals Seasonality and factors associated with cryptosporidiosis among individuals with HIV infection

1998 ◽  
Vol 121 (1) ◽  
pp. 197-204 ◽  
Author(s):  
F. SORVILLO ◽  
G. BEALL ◽  
P. A. TURNER ◽  
V. L. BEER ◽  
A. A. KOVACS ◽  
...  
Keyword(s):  
Los Angeles ◽  
Hiv Infection ◽  
Ethnic Groups ◽  
Los Angeles County ◽  
Strong Association ◽  
Age Groups ◽  
Factors Associated ◽  
Increased Risk ◽  
Cd4 Lymphocyte ◽  
Racial Ethnic

The seasonality and factors associated with Cryptosporidium infection were assessed in a cohort of HIV-infected patients in Los Angeles County to better define the epidemiology of cryptosporidiosis among individuals with HIV. Data were analysed from a cohort of 4247 patients [ges ]13 years of age with HIV infection enrolled from four outpatient facilities in Los Angeles, 1990–6. Cryptosporidiosis was diagnosed in 120 (2·8%) patients. Among the 1296 individuals with complete follow-up until death, cryptosporidiosis occurred in 69 (5·3%). The seasonal rate of cryptosporidiosis showed a modest bimodal trend with the highest rates occurring in March–May and September–October. There was no difference in the rate of cryptosporidiosis for the periods of heaviest rainfall (December–March) and low rainfall (April–November). Infection rates were higher among males (1·59 per 100 person-years) than females (0·92) and lower in blacks (0·98) than other racial/ethnic groups (1·80). A significant trend of decreasing cryptosporidiosis was observed with increasing age, with the highest rate (2·34) in the 13–34 year age group. A strong association between cryptosporidiosis and CD4+ count was noted. These data suggest that cryptosporidiosis among HIV-infected individuals in Los Angeles County exhibits a modest spring and fall seasonality. This pattern of occurrence of cryptosporidiosis appears temporally unrelated to local rainfall patterns. Our findings suggest that HIV-infected men, individuals in younger age groups and those with CD4+ lymphocyte counts <100×106/l are at increased risk of cryptosporidiosis. Blacks with HIV infection appear less likely than other racial/ethnic groups to be diagnosed with Cryptosporidium infection. These results may provide insight into possible routes of transmission and sources of cryptosporidiosis infection in individuals with HIV.

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