scholarly journals Performance of factor IX extended half‐life product measurements in external quality control assessment programs

2020 ◽  
Vol 18 (8) ◽  
pp. 1874-1883 ◽  
Author(s):  
Angelique Nederlof ◽  
Steve Kitchen ◽  
Piet Meijer ◽  
Marjon Cnossen ◽  
Nae Ali Pour ◽  
...  
Keyword(s):  
Quality Control ◽  
Half Life ◽  
Factor Ix ◽  
External Quality Control ◽  
External Quality

Interlaboratory evaluation of salicylate interference in colorimetric acetaminophen methods and its clinical significance.

1985 ◽  
Vol 31 (7) ◽  
pp. 1158-1162 ◽  
Author(s):  
R W Jenny
Keyword(s):  
Quality Control ◽  
Clinical Significance ◽  
Correction Factor ◽  
Half Life ◽  
Laboratory Data ◽  
Control Program ◽  
Hepatic Necrosis ◽  
External Quality Control ◽  
External Quality ◽  
Quality Control Program

Abstract Serum specimens with concentrations simulating an overdose of salicylate and acetaminophen were submitted to laboratories participating in an external quality-control program, to evaluate both the magnitude of salicylate interference in colorimetric acetaminophen methods and the clinical significance of the interference. The apparent acetaminophen concentration determined by nitration methods was increased by about 0.70 mg/L per milligram of salicylate per deciliter. Of those laboratories using nitration procedures, 25% do not routinely correct for salicylate and 66% use the (incorrect) correction factor provided by a kit manufacturer. Laboratory data, as they would have been reported to physicians, were used to estimate the acetaminophen half-life and were also applied to a nomogram used to assess the probability of hepatotoxicity. Interference by salicylate in the simulated overdose of 10 g (total dose) of each drug falsely indicated impending hepatic necrosis unless the appropriate correction factor was used. Laboratories using nitration procedures should screen samples submitted for acetaminophen assay for the presence of salicylate and, if present, either use a method specific for acetaminophen or utilize a correction factor determined in-house.

scholarly journals The Schemes of External Quality Control in Laboratory Medicine in the Balkans

2007 ◽  
Vol 26 (3) ◽  
pp. 245-247
Author(s):  
Petros Karkalousos
Keyword(s):  
Quality Control ◽  
Scientific Community ◽  
Clinical Chemistry ◽  
Laboratory Medicine ◽  
External Quality Control ◽  
External Quality ◽  
The Balkans ◽  
Control Schemes ◽  
Balkan Countries ◽  
Balkan Region

The Schemes of External Quality Control in Laboratory Medicine in the Balkans There are many differences between the national External Quality Control Schemes all around Europe, but the most important ones are certainly those between the countries of the Balkan region. These differences are due to these countries' different political and financial development, as well as to their tradition and the development of clinical chemistry science in each one. Therefore, there are Balkan countries with very developed EQAS and others where there is no such a scheme. Undoubtedly, the scientific community in these countries wants to develop EQAS despite of the financial and other difficulties.

scholarly journals Necessity of External Quality Control for anti-Mycoplasma pneumoniae IgM antibodies

2008 ◽  
Vol 23 (2) ◽  
Author(s):  
Massimo De Paschale ◽  
Luisa Belvisi ◽  
Debora Cagnin ◽  
Teresa Cerulli ◽  
Maria Teresa Manco ◽  
...  
Keyword(s):  
Quality Control ◽  
Mycoplasma Pneumoniae ◽  
External Quality Control ◽  
External Quality ◽  
Igm Antibodies

scholarly journals External Quality Assessment in the Evaluation of Laboratory Performance of Faecal Culture

2017 ◽  
Vol 10 ◽  
pp. 117863611769125
Author(s):  
Salla J Kiiskinen ◽  
Tarja Ojanen ◽  
Yvonne Björkman ◽  
Harri Laitinen ◽  
Anja Siitonen
Keyword(s):  
Public Health ◽  
Quality Control ◽  
External Quality Assessment ◽  
False Negative ◽  
The Other ◽  
Epidemiological Surveillance ◽  
External Quality Control ◽  
External Quality ◽  
Faecal Culture

In Finland, all laboratories carrying out diagnostics of infectious diseases in humans are approved by the Regional State Administrative Agencies and are obligated to participate in External Quality Assurance rounds. Performance in these rounds is thought to reflect the quality of laboratory work. In the 6-year study period, 17 Finnish laboratories received 48 simulated faecal specimens for the culturing of diarrhoeal pathogens, yielding altogether 586 faecal culture External Quality Control specimens and 581 reports. The results were correct in 92% of all reports and in 67% of all specimens. False-negative Salmonella results were given for 2 of the 18 specimens, one with biochemically atypical Salmonella strain and the other with a low count of Salmonella cells. False-negative Shigella report was given for 6 of the 7 specimens in some participating laboratory. Detection of all common faecal pathogens is especially relevant to patient safety, public health, and epidemiological surveillance.

scholarly journals Paracetamol: A Report of a Regional Quality Control Scheme

1979 ◽  
Vol 16 (1-6) ◽  
pp. 265-270 ◽  
Author(s):  
J. Epton
Keyword(s):  
Quality Control ◽  
Group Performance ◽  
Clinical Importance ◽  
External Quality Control ◽  
External Quality ◽  
Limits Of Detection ◽  
Trouble Shooting ◽  
Control Scheme ◽  
Considerable Impact ◽  
Quality Control Scheme

The results from an external quality control scheme for the assay of paracetamol in serum are reported. A preferential method of assay has not become evident, but, as a result of the scheme, some laboratories have changed or modified their techniques or have re-established the limits of detection. The majority of laboratories were able to estimate paracetamol satisfactorily at those levels which are of clinical importance. The overall group performance has shown little change. The programme has had considerable impact in so far as it has led to a mutually useful interchange of information and trouble shooting.

scholarly journals P6.031 Implementation of a Programme of External Quality Control Evaluation For Rapid HIV Testing in Brazil

2013 ◽  
Vol 89 (Suppl 1) ◽  
pp. A379.1-A379
Author(s):  
A Bolzan ◽  
M Bazzo ◽  
E Santos ◽  
E Ayer ◽  
L Wildner ◽  
...  
Keyword(s):  
Quality Control ◽  
Hiv Testing ◽  
External Quality Control ◽  
External Quality ◽  
Rapid Hiv Testing ◽  
Control Evaluation
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