scholarly journals Comparison of multiple electrode aggregometry with lumi-aggregometry for the diagnosis of patients with mild bleeding disorders

2017 ◽  
Vol 15 (10) ◽  
pp. 2045-2052 ◽  
Author(s):  
R. Al Ghaithi ◽  
S. Drake ◽  
S. P. Watson ◽  
N. V. Morgan ◽  
P. Harrison
Keyword(s):  
Bleeding Disorders ◽  
Multiple Electrode Aggregometry ◽  
Mild Bleeding Disorders ◽  
Multiple Electrode

Usefulness of multiple electrode aggregometry as a screening tool for bleeding disorders in a pediatric hospital

Platelets ◽  
2018 ◽  
Vol 30 (4) ◽  
pp. 498-505 ◽  
Author(s):  
Thorsten Haas ◽  
Melissa M. Cushing ◽  
Stephanie Varga ◽  
Séverine Gilloz ◽  
Markus Schmugge
Keyword(s):  
Screening Tool ◽  
Bleeding Disorders ◽  
Pediatric Hospital ◽  
Multiple Electrode Aggregometry ◽  
Multiple Electrode

scholarly journals Platelet Function Disturbance During Veno-Venous ECMO in ARDS Patients Assessed by Multiple Electrode Aggregometry—A Prospective, Observational Cohort Study

2019 ◽  
Vol 8 (7) ◽  
pp. 1056 ◽  
Author(s):  
Saskia Wand ◽  
Jan Felix Huber-Petersen ◽  
Joern Schaeper ◽  
Claudia Binder ◽  
Onnen Moerer
Keyword(s):  
Platelet Aggregation ◽  
Platelet Function ◽  
Extracorporeal Circulation ◽  
Inverse Correlation ◽  
Negative Effects ◽  
Multiple Electrode Aggregometry ◽  
Observational Cohort ◽  
And Function ◽  
The Impact ◽  
Multiple Electrode

Extracorporeal (veno-venous) membrane oxygenation (vvECMO) has been shown to have negative effects on platelet number and function. This study aimed to gain more information about the impact of vvECMO on platelet function assessed by multiple electrode aggregometry (MEA). Twenty patients with the indication for vvECMO were included. Platelet function was analyzed using MEA (Multiplate®) before (T-1), 6 h (T0), one (T1), two (T2), three (T3), and seven (T4) days after the beginning of vvECMO. Median aggregational measurements were already below the normal reference range before vvECMO initiation. Platelet aggregation was significantly reduced 6 h after vvECMO initiation compared to T-1 and spontaneously recovered with a significant increase at T2. Platelet count dropped significantly between T-1 and T0 and continuously decreased between T0 and T4. At T4, ADP-induced platelet aggregation showed an inverse correlation with the paO2 in the oxygenator. Platelet function should be assessed by MEA before the initiation of extracorporeal circulation. Although ECMO therapy led to a further decrease in platelet aggregation after 6 h, all measurements had recovered to baseline on day two. This implies that MEA as a whole blood method might not adequately reflect the changes in platelet function in the later stages of extracorporeal circulation.

Cost-Effectiveness of POC Coagulation Testing Using Multiple Electrode Aggregometry

2016 ◽  
Vol 62 (06/2016) ◽  
Author(s):  
Niels Straub ◽  
Ekaterina Bauer ◽  
Seema Agarwal ◽  
Patrick Meybohm ◽  
Kai Zacharowski ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Multiple Electrode Aggregometry ◽  
Coagulation Testing ◽  
Multiple Electrode
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