Sleep extension and metabolic health in male overweight/obese short sleepers: A randomised controlled trial

2021 ◽  
Author(s):  
Iuliana Hartescu ◽  
David J. Stensel ◽  
Alice E. Thackray ◽  
James A. King ◽  
James L. Dorling ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Metabolic Health ◽  
Sleep Extension ◽  
Randomised Controlled

scholarly journals The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 1042
Author(s):  
Nicholas Phillips ◽  
Julie Mareschal ◽  
Nathalie Schwab ◽  
Emily Manoogian ◽  
Sylvie Borloz ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Smartphone Application ◽  
Metabolic Health ◽  
Dietary Advice ◽  
Processed Food ◽  
Significant Difference ◽  
Randomised Controlled ◽  
Pragmatic Randomised Controlled Trial

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships between eating duration, unprocessed and processed food consumption and metabolic health. During 4 weeks of observation, 213 adults used a smartphone application to record food and drink consumption, which was annotated for food processing levels following the NOVA classification. Low consumption of unprocessed food and low physical activity showed significant associations with multiple MS components. Second, in a pragmatic randomised controlled trial, we compared the metabolic benefits of 12 h time-restricted eating (TRE) to standard dietary advice (SDA) in 54 adults with an eating duration > 14 h and at least one MS component. After 6 months, those randomised to TRE lost 1.6% of initial body weight (SD 2.9, p = 0.01), compared to the absence of weight loss with SDA (−1.1%, SD 3.5, p = 0.19). There was no significant difference in weight loss between TRE and SDA (between-group difference −0.88%, 95% confidence interval −3.1 to 1.3, p = 0.43). Our results show the potential of smartphone records to predict metabolic health and highlight that further research is needed to improve individual responses to TRE such as a shorter eating window or its actual clock time.

scholarly journals The effects of time-restricted eating vs. standard dietary advice on weight, metabolic health and the consumption of processed food: A pragmatic randomised controlled trial in community-based adults

2021 ◽  
Author(s):  
Nicholas Edward Phillips ◽  
Julie Mareschal ◽  
Nathalie Schwab ◽  
Emily N.C. Manoogian ◽  
Sylvie Borloz ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Metabolic Health ◽  
Dietary Advice ◽  
Individual Response ◽  
Processed Food ◽  
Significant Difference ◽  
Randomised Controlled ◽  
Pragmatic Randomised Controlled Trial

AbstractThe prevalence of metabolic syndrome (MS) is increasing, affecting approximately 1 billion people. Weight loss is key to control MS components, i.e. central obesity, hypertension, prediabetes, and dyslipidaemia. Here, we characterised the relationships between eating duration, unprocessed and processed food consumption, and metabolic health. In a 4-week observation phase, 213 Swiss adults recorded consumed meals and drinks with a smartphone application, and these were annotated for food processing levels according to the NOVA classification. Regression analysis showed that consumption of unprocessed food items showed the highest number of significant relationships with MS components after age and sex. The fraction of unprocessed food out of all ingestion events was positively associated with HDL cholesterol and negatively associated with BMI, waist circumference and triglycerides. Next, in a pragmatic randomised controlled trial, we tested whether 12h time-restricted eating (TRE) leads to metabolic benefits compared to standard dietary advice (SDA), in 54 adults who ate >14h per 24h cycle and had at least one MS component. After 6 months, those randomised to TRE lost 1.6% of initial body weight (SD 2.9, p = 0.01), compared to the absence of weight loss with SDA (−1.1%, SD 3.5, p = 0.19). Thus, there was no significant difference in weight loss between TRE and SDA (between-group difference −0.5 kg, 95% confidence interval −2.4 to 1.4, p = 0.61). Overall, our results show the potential of smartphone records to predict metabolic health, and highlight that further research is needed to understand individual response to TRE and SDA.

Filmed versus Live Social Contact Interventions to Reduce Stigma: A Randomised Controlled Trial

2012 ◽  
Author(s):  
Sarah Clement ◽  
Adrienne van Nieuwenhuizen ◽  
Aliya Kassam ◽  
Ian Norman ◽  
Clare Flach ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Social Contact ◽  
Randomised Controlled
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