Cumulative incidence and relative risk of sleep problems among children and adolescents with newly diagnosed neurodevelopmental disorders: A nationwide register‐based study

2020 ◽  
Author(s):  
Allan Hvolby ◽  
Jakob Christensen ◽  
Christiane Gasse ◽  
Søren Dalsgaard ◽  
Julie Werenberg Dreier
Keyword(s):  
Relative Risk ◽  
Children And Adolescents ◽  
Neurodevelopmental Disorders ◽  
Cumulative Incidence ◽  
Sleep Problems ◽  
Newly Diagnosed

Deficient Emotional Self-Regulation and Sleep Problems in ADHD with and without Pharmacological Treatment

2021 ◽  
pp. 108705472098624
Author(s):  
Miriam Sanabra ◽  
Tary Gómez-Hinojosa ◽  
Núria Grau ◽  
Jose A. Alda
Keyword(s):  
Children And Adolescents ◽  
Pharmacological Treatment ◽  
Healthy Subjects ◽  
Child Behavior Checklist ◽  
Sleep Problems ◽  
Self Regulation ◽  
Attention Problems ◽  
Control Group ◽  
Newly Diagnosed ◽  
Sleep Parameters

Objective: The purpose of this study is to analyse DESR and its influence on sleep parameters in three different groups of children and adolescents: a group newly diagnosed with ADHD naïve, a group with ADHD under pharmacological treatment and a control group. Method: Subjects were a total of 327 children and adolescents. Two groups diagnosed with ADHD: 108 medication-naïve and 80 under pharmacological treatment; and one group with 136 healthy subjects. DESR was defined using anxious/depressed, attention problems and aggressive behaviors (AAA) scales from the Child Behavior Checklist (CBCL), and sleep through the Sleep Disturbance Scale for Children. Results: Significant differences were found comparing the three groups ( p = .001), with a significantly higher profile on DESR in ADHD subjects, especially those who did not undergo treatment, and a positive correlation between DESR and sleep. Conclusion: Children and adolescents with ADHD without treatment present higher DESR than healthy controls and consequently higher sleep problems.

scholarly journals Migration, family dysfunction and psychotic symptoms in children and adolescents

2005 ◽  
Vol 186 (5) ◽  
pp. 442-443 ◽  
Author(s):  
Luis R. Patino ◽  
Jean-Paul Selten ◽  
Herman van Engeland ◽  
Jan H. M. Duyx ◽  
René S. Kahn ◽  
...  
Keyword(s):  
Relative Risk ◽  
Children And Adolescents ◽  
Cross Sectional Study ◽  
Family Dysfunction ◽  
Psychotic Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
Migration History ◽  
And Migration

SummaryA cross-sectional study of 3426 referred children and adolescents showed that the presence of both migration history and family dysfunction was associated with a fourfold (95% CI 2–9) higher risk of psychotic symptoms compared with the absence of these factors. The relative risk was 2 (95% CI 1–4) for migration history only. Interaction between migration history and family dysfunction accounted for 58% (95% CI 5–91%) of those with psychotic symptoms. These results suggest a relationship between family dysfunction and migration in the development of psychosis.

scholarly journals Determinants of cardiac disease in newly diagnosed patients with acromegaly: results of a 10 year survey study

2011 ◽  
Vol 165 (5) ◽  
pp. 713-721 ◽  
Author(s):  
Annamaria Colao ◽  
Rosario Pivonello ◽  
Ludovica Francesca Stella Grasso ◽  
Renata Simona Auriemma ◽  
Mariano Galdiero ◽  
...  
Keyword(s):  
Relative Risk ◽  
Glucose Tolerance ◽  
Disease Duration ◽  
Systolic Dysfunction ◽  
Density Lipoprotein ◽  
Left Ventricular ◽  
Cardiac Complications ◽  
Model Assessment ◽  
Newly Diagnosed ◽  
Acromegalic Cardiomyopathy

ContextThe most frequent cause of death in acromegaly is cardiomyopathy.ObjectiveTo evaluate determinants of acromegalic cardiomyopathy.DesignObservational, open, controlled, retrospective study.SubjectsTwo hundred and five patients with newly diagnosed active acromegaly (108 women and 97 men; median age 44 years) and 410 non-acromegalic subjects sex- and age-matched with the patients.Main outcome measuresLeft ventricular (LV) mass index (LVMi), transmitral inflow early-to-atrial (E/A) peak velocity ratio, and LV ejection fraction (LVEF) were measured by Doppler echocardiography to determine the prevalence of LV hypertrophy (LVH), diastolic and systolic dysfunction. The role of age, estimated disease duration, body mass index, GH and IGF1 levels, systolic and diastolic blood pressure, lipid profile and glucose tolerance in determining different features of the acromegalic cardiomyopathy was investigated.ResultsCompared with controls, the patients had lower E/A, LVEF, high-density lipoprotein (HDL)-cholesterol levels and higher LVMi, total- and low-density lipoprotein (LDL)-cholesterol, triglycerides, glucose and insulin levels, homeostatic model assessment of insulin resistance (HOMA-R) and HOMA-β. The relative risk to develop mild (odds ratio (OR)=1.67 (1.05–2.66); P=0.027) or severe hypertension (OR=1.58 (1.04–2.32); P=0.027), arrhythmias (OR=4.93 (1.74–15.9); P=0.001), impaired fasting glucose/impaired glucose tolerance (OR=2.65 (1.70–4.13); P<0.0001), diabetes (OR=2.14 (1.34–3.40); P=0.0009), LVH (OR=11.9 (7.4–19.5); P<0.0001), diastolic (OR=3.32 (2.09–5.31); P<0.0001) and systolic dysfunction (OR=14.2 (6.95–32.2); P<0.0001), was higher in acromegaly. The most important predictor of LVH (t=2.4, P=0.02) and systolic dysfunction (t=−2.77, P=0.006) was disease duration and that of diastolic dysfunction was patient's age (t=−3.3, P=0.001). Patients with an estimated disease duration of >10 years had a relative risk to present cardiac complications three times higher than patients with estimated disease duration ≤5 years.ConclusionsThe prevalence of different features of cardiomyopathy is 3.3–14.2 times higher in the acromegalic than in the non-acromegalic population. The major determinant of cardiomyopathy is disease duration.

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