Non‐inflammatory joint effusions as a presenting sign of hypothyroidism in a dog

2021 ◽  
Author(s):  
D. Kelly ◽  
R. Quinn
Keyword(s):  
Joint Effusions

Reliability of Total Nucleated Cell Counts in the Setting of Hip Arthroplasty

2020 ◽  
Author(s):  
Lauren N Pearson ◽  
Robert L Schmidt ◽  
Kenneth Cahoon ◽  
Christopher E Pelt
Keyword(s):  
Synovial Fluid ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Metal Debris ◽  
Total Hip ◽  
Cell Counts ◽  
History Of ◽  
Joint Effusions ◽  
Automated Instruments ◽  
Automated Methods

Abstract Background Total nucleated cell (TNC) count and differential are used to classify joint effusions as inflammatory or noninflammatory. Further diagnostic evaluation and management is contingent on this classification. TNC count can be measured by automated analyzers or by manual assessment using a hemocytometer. Studies have raised concerns regarding the accuracy of TNC counts measured by automated instruments, particularly in the setting of joint arthroplasty. The objective of this study was to determine whether metallosis, a complication of total hip arthroplasty in which metal debris accumulates in periprosthetic tissues and synovial fluid, is associated with inaccurate TNC counts in synovial fluid. Methods We compared the accuracy of cell counts measured by the Sysmex XN-1000 and Beckman Coulter Iris iQ200 with the gold standard of manual assessment using a hemocytometer in synovial fluid from patients with suspected metallosis and in fluid obtained from controls from patients with native joints and a history of arthroplasty for other indications. Results TNC counts produced by automated analyzers were associated with increased levels of discordance (relative to manual counts) in patients with metallosis. Metallosis was not associated with increased levels of discordance for RBC counts or WBC differentials. The Sysmex XN flagged all but 1 metallosis sample for manual verification of the results. Conclusions Automated methods are generally reliable for analysis of synovial fluid. TNC counts can be inaccurate in the context of metallosis following total hip arthroplasty. Laboratories should correlate automated cell counts with a microscopic assessment of the specimen, as recommended by instrument manufacturers.

scholarly journals Isolation of an interleukin-1-like factor from human joint effusions

1983 ◽  
Vol 26 (8) ◽  
pp. 975-983 ◽  
Author(s):  
D. D. Wood ◽  
E. J. Ihrie ◽  
C. A. Dinarello ◽  
P. L. Cohen
Keyword(s):  
Interleukin 1 ◽  
Joint Effusions ◽  
Human Joint

scholarly journals Early Intra-Articular Complement Activation in Ankle Fractures

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Hagen Schmal ◽  
Gian M. Salzmann ◽  
Philipp Niemeyer ◽  
Elia Langenmair ◽  
Renfeng Guo ◽  
...  
Keyword(s):  
Complement Activation ◽  
Case Series ◽  
Ankle Fractures ◽  
Complement Components ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Reactive Protein ◽  
Fluid Analysis ◽  
Joint Effusions ◽  
Prospective Case Series

Cytokine regulation possibly influences long term outcome following ankle fractures, but little is known about synovial fracture biochemistry. Eight patients with an ankle dislocation fracture were included in a prospective case series and matched with patients suffering from grade 2 osteochondritis dissecans (OCD) of the ankle. All fractures needed external fixation during which joint effusions were collected. Fluid analysis was done by ELISA measuring aggrecan, bFGF, IL-1β, IGF-1, and the complement components C3a, C5a, and C5b-9. The time periods between occurrence of fracture and collection of effusion were only significantly associated with synovial aggrecan and C5b-9 levels (P<0.001). Furthermore, synovial expressions of both proteins correlated with each other (P<0.001). Although IL-1βexpression was relatively low, intra-articular levels correlated with C5a (P<0.01) and serological C-reactive protein concentrations 2 days after surgery (P<0.05). Joint effusions were initially dominated by neutrophils, but the portion of monocytes constantly increased reaching 50% at day 6 after fracture (P<0.02). Whereas aggrecan and IL-1βconcentrations were not different in fracture and OCD patients, bFGF, IGF-1, and all complement components were significantly higher concentrated in ankle joints with fractures (P<0.01). Complement activation and inflammatory cell infiltration characterize the joint biology following acute ankle fractures.

scholarly journals Lipoma Arborescens in a 16-year old male: A case report

2021 ◽  
Author(s):  
Paa BAIDOO ◽  
Emile Tano ◽  
Frank Nketiah Boakye ◽  
Majeedallahi Al-hassan ◽  
Gaddiel Yorke ◽  
...  
Keyword(s):  
Case Report ◽  
Range Of Motion ◽  
Laboratory Analysis ◽  
Incisional Biopsy ◽  
Lipoma Arborescens ◽  
Plain Radiographs ◽  
Adults And Children ◽  
Joint Effusions ◽  
Work Up

Lipoma arborescens is a benign intra-articular tumor characterized by joint effusions, pain and reduced range of motion. It is rare in adults and children. We present a case of Lipoma arborescens in a 16 year old male. The work up involved plain radiographs, MRI, incisional biopsy and laboratory analysis.

Ultrasound of the Calf, Ankle, and Foot

2019 ◽  
pp. 376-381
Author(s):  
Yoav Morag
Keyword(s):  
Plantar Fasciitis ◽  
Region Of Interest ◽  
Imaging Study ◽  
Posterior Tibial Tendon ◽  
Peroneal Tendon ◽  
Tendon Ruptures ◽  
Morton Neuroma ◽  
Joint Effusions ◽  
Injured Tendon ◽  
Ankle And Foot

Chapter 125 discusses US examination of the calf, ankle, and foot, which is frequently performed to evaluate for muscle, tendon, and ligamentous injuries; joint effusions and synovitis; bursitis; plantar fasciitis; and Morton neuroma. US measurements of Achilles tendon ruptures in different ankle positions may help in guiding treatment selection. Dynamic US evaluation is the imaging study of choice to evaluate for peroneal tendon dislocation and intrasheath subluxation. The posterior tibial tendon (PTT) is the most commonly injured tendon at the medial aspect of the ankle which can be readily evaluated with US. US scanning may be comprehensive or focused to the region of interest.

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