Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis

2021 ◽  
Author(s):  
Yuta Shimizu ◽  
Tomoko Takeda‐Kawaguchi ◽  
Izumi Kuroda ◽  
Yasuaki Hotta ◽  
Hideya Kawasaki ◽  
...  
Keyword(s):  
Bone Loss ◽  
Dental Pulp ◽  
Dental Pulp Cells ◽  
Pulp Cells ◽  
Experimental Periodontitis

scholarly journals The Preparation and Characterization of Chitosan-Based Hydrogels Cross-Linked by Glyoxal

Materials ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2449
Author(s):  
Beata Kaczmarek-Szczepańska ◽  
Olha Mazur ◽  
Marta Michalska-Sionkowska ◽  
Krzysztof Łukowicz ◽  
Anna Maria Osyczka
Keyword(s):  
Thermal Stability ◽  
Tannic Acid ◽  
Dental Pulp ◽  
Blood Compatibility ◽  
Dental Pulp Cells ◽  
Preliminary Assessment ◽  
Human Dental Pulp Cells ◽  
Human Dental Pulp ◽  
Pulp Cells

In this study, hydrogels based on chitosan cross-linked by glyoxal have been investigated for potential medical applications. Hydrogels were loaded with tannic acid at different concentrations. The thermal stability and the polyphenol-releasing rate were determined. For a preliminary assessment of the clinical usefulness of the hydrogels, they were examined for blood compatibility and in the culture of human dental pulp cells (hDPC). The results showed that after immersion in a polyphenol solution, chitosan/glyoxal hydrogels remain nonhemolytic for erythrocytes, and we also did not observe the cytotoxic effect of hydrogels immersed in tannic acid (TA) solutions with different concentration. Tannic acid was successfully released from hydrogels, and its addition improved material thermal stability. Thus, the current findings open the possibility to consider such hydrogels in clinics.

scholarly journals Cytotoxicity assessment of different doses of ozonated water on dental pulp cells

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ferdiye Küçük ◽  
Sibel Yıldırım ◽  
Serap Çetiner
Keyword(s):  
Cell Viability ◽  
Repeated Measures ◽  
Dental Pulp ◽  
Control Group ◽  
Dental Pulp Cells ◽  
Time Points ◽  
Significant Difference ◽  
Pulp Cells ◽  
Time Point ◽  
Ozonated Water

Abstract Background The purpose of this study was to assess the cytotoxicity of various concentrations of ozonated water (OW) on human primary dental pulp cells. Methods Human primary dental pulp cells were isolated from exfoliated primary canine teeth of an 11-year-old patient with good systemic and oral health. Afterwards, cells were divided into 6 experimental groups; four groups of OW in concentrations of 2 mg/L, 4 mg/L, 8 mg/L, and 16 mg/L, untreated control group, and cell culture without cells. Cytotoxicity was evaluated after exposure for 5-min exposure using Mosmann’s Tetrazolium Toxicity (MTT) assay at 0 h and 48 h time points. Data were analyzed using a repeated measures analysis of variance and Post-hoc tests were performed using Bonferroni correction for multiple comparisons. Results All experimental groups showed proliferation at 0 h time point. However, all groups also experienced a decrease in overtime at 48 h time point (p < 0.05). At both time points 2 mg/L OW showed the highest cell viability as well as proliferation. At 0 h time point, the increase in cell viability for all experimental groups was found statistically significant when compared to positive control group (p < 0.05). At 48 h time point, although 8 mg/L and 16 mg/L OW showed statistically significant reduction in compare to 0 h time point, 2 mg/L and 4 mg/L OW groups didn’t experience any statistically significant difference (p < 0.05). Conclusion Considering our findings, due to ozonated water's induced a higher proliferation rate of dental pulp cells, indicating their biocompatibility and a possible adjuvant on irrigating agent in regenerative endodontic procedures.

The molecular functions of Biodentine and MTA in LPS‐induced inflamed dental pulp cells

2021 ◽  
Author(s):  
M.C. Wang ◽  
H.F. Tu ◽  
K.W. Chang ◽  
S.C. Lin ◽  
L.Y. Yeh ◽  
...  
Keyword(s):  
Dental Pulp ◽  
Dental Pulp Cells ◽  
Pulp Cells ◽  
Molecular Functions

HGF Enhanced Proliferation and Differentiation of Dental Pulp Cells

2006 ◽  
Vol 32 (8) ◽  
pp. 736-741 ◽  
Author(s):  
Ling Ye ◽  
Li Peng ◽  
Hong Tan ◽  
Xuedong Zhou
Keyword(s):  
Dental Pulp ◽  
Dental Pulp Cells ◽  
Proliferation And Differentiation ◽  
Pulp Cells

Kallikrein Promotes Inflammation in Human Dental Pulp Cells Via Protease-Activated Receptor-1

2016 ◽  
Vol 117 (7) ◽  
pp. 1522-1528 ◽  
Author(s):  
Tomomi Hayama ◽  
Naoto Kamio ◽  
Tatsu Okabe ◽  
Koichiro Muromachi ◽  
Kiyoshi Matsushima
Keyword(s):  
Dental Pulp ◽  
Dental Pulp Cells ◽  
Human Dental Pulp Cells ◽  
Human Dental Pulp ◽  
Pulp Cells ◽  
Protease Activated Receptor 1

Effect of Nifedipine on the Differentiation of Human Dental Pulp Cells Cultured with Mineral Trioxide Aggregate

2013 ◽  
Vol 39 (6) ◽  
pp. 801-805 ◽  
Author(s):  
Su-Mi Woo ◽  
Yun-Chan Hwang ◽  
Hoi-Soon Lim ◽  
Nam-Ki Choi ◽  
Sun-Hun Kim ◽  
...  
Keyword(s):  
Dental Pulp ◽  
Mineral Trioxide Aggregate ◽  
Dental Pulp Cells ◽  
Human Dental Pulp Cells ◽  
Human Dental Pulp ◽  
Pulp Cells ◽  
Cells Cultured

PLGA artificial nerve conduits with dental pulp cells promote facial nerve regeneration

2011 ◽  
Vol 5 (10) ◽  
pp. 823-830 ◽  
Author(s):  
Ryo Sasaki ◽  
Shunsuke Aoki ◽  
Masayuki Yamato ◽  
Hiroto Uchiyama ◽  
Keiji Wada ◽  
...  
Keyword(s):  
Facial Nerve ◽  
Nerve Regeneration ◽  
Dental Pulp ◽  
Dental Pulp Cells ◽  
Nerve Conduits ◽  
Pulp Cells
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