Methyl donor supplementation alters serum leptin levels and increases appetite but not body weight in cross‐fostered male Syrian hamster offspring ( Mesocricetus auratus )

2021 ◽  
Author(s):  
Bülent Gündüz ◽  
Darren K. Okimoto
Keyword(s):  
Body Weight ◽  
Syrian Hamster ◽  
Mesocricetus Auratus ◽  
Serum Leptin ◽  
Methyl Donor

Age-related and photoperiodic variation of the DAZ gene family in the testis of the Syrian hamster (Mesocricetus auratus)

Zygote ◽  
2018 ◽  
Vol 26 (2) ◽  
pp. 127-134 ◽  
Author(s):  
Candela Rocío González ◽  
Luciana Moverer ◽  
Ricardo Saúl Calandra ◽  
Silvia Inés González-Calvar ◽  
Alfredo Daniel Vitullo
Keyword(s):  
Protein Expression ◽  
Gene Family ◽  
Syrian Hamster ◽  
Mesocricetus Auratus ◽  
Cell Number ◽  
The Novel ◽  
Age Related ◽  
Mrna And Protein Expression ◽  
Long Photoperiod ◽  
Daz Gene

SummaryThe Deleted in AZoospermia (DAZ) gene family regulates the development, maturation and maintenance of germ cells and spermatogenesis in mammals. The DAZ family consists of two autosomal genes, Boule and Dazl (Daz-like), and the Daz gene on chromosome Y. The aim of this study was to analyze the localization of DAZL and BOULE during testicular ontogeny of the seasonal-breeding Syrian hamster, Mesocricetus auratus. We also evaluated the testicular expression of DAZ family genes under short- or long-photoperiod conditions. In the pre-pubertal and adult testis, DAZL protein was found mainly in spermatogonia. BOULE was found in the spermatogonia from 20 days of age and during the pre-pubertal and adult period it was also detected in spermatocytes and round spermatids. DAZL and BOULE expression in spermatogonia was strictly nuclear only in 20-day-old hamsters. We also detected the novel mRNA and protein expression of BOULE in Leydig cells. In adult hamsters, Dazl expression was increased in regressed testis compared with non-regressed testis and DAZL protein expression was restricted to primary spermatocytes in regressed testis. These results show that DAZL and BOULE are expressed in spermatogonia at early stages in the Syrian hamster, then both proteins translocate to the cytoplasm when meiosis starts. In the adult regressed testis, the absence of DAZL in spermatogonia might be related to the decrease in germ cell number, suggesting that DAZ gene family expression is involved in changes in seminiferous epithelium during photoregression.

scholarly journals Spontaneous glomerular basement membrane changes in the golden Syrian hamster (Mesocricetus auratus): a light and electron microscope study

1978 ◽  
Vol 12 (4) ◽  
pp. 207-211 ◽  
Author(s):  
E. A. E. Van Marck ◽  
W. Jacob ◽  
A. M. Deelder ◽  
P. L. J. Gigase
Keyword(s):  
Electron Microscope ◽  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Syrian Hamster ◽  
Microscope Study ◽  
Electron Microscope Study ◽  
Mesocricetus Auratus ◽  
Golden Syrian Hamster ◽  
Membrane Changes ◽  
Apparently Healthy

Changes in apparently healthy hamsters, consistent with proteinuria, are reported, but no IgG deposits or amyloid in the glomeruli were detected. Further investigation is required into the significance and the aetiology of these, as yet, obscure alterations.

New Embryological Evidence for the Formation of Quadricuspid Aortic Valves in the Syrian Hamster (Mesocricetus auratus)

1999 ◽  
Vol 121 (1) ◽  
pp. 89-94 ◽  
Author(s):  
B. Fernández ◽  
A.C. Durán ◽  
A. Martire ◽  
D. López ◽  
V. Sans-Coma
Keyword(s):  
Syrian Hamster ◽  
Mesocricetus Auratus ◽  
Aortic Valves

Abstract 192: Intra-Placental Gene Transfer of Human Insulin-Like Growth Factor-1 Reprograms Fetal Predisposition to Obesity in Intra-uterine Growth Restriction

Hypertension ◽  
2012 ◽  
Vol 60 (suppl_1) ◽  
Author(s):  
Khaled R Omar ◽  
Helen Jones ◽  
Swathi Balaji ◽  
Young Nam ◽  
Kitcheol Kil ◽  
...  
Keyword(s):  
Body Weight ◽  
Birth Weight ◽  
Gene Transfer ◽  
Food Consumption ◽  
Mice Model ◽  
Fasting Serum ◽  
Chi Square ◽  
Serum Leptin ◽  
Increased Risk ◽  
Fetal Reprogramming

We have shown that intra placental adenoviral mediated gene transfer of (Ad hIGF1) corrects birth weight in a new surgical mouse IUGR model. Evidence shows that IUGR offspring are predisposed to increased risk of adult diseases. We hypothesized that intraplacental Ad hIGF1 not only restores birth weight in this IUGR model but prevents adult onset obesity through fetal reprogramming Laparotomy was done at day 18 on time pregnant C57BL/6J mice, divided into 3 groups. Control: Sham operated; IUGR: birth weight <10% for gestational age; Treated: IUGR+IGF1; n= 16. Pups were delivered on day 20, cross fostered to surrogate CD1 mice, sorted by gender at 4 weeks and followed up to 24 weeks. Body weight, fat pad weight, fasting serum leptin and food consumption were measured. Data analyzed by Chi-square or ANOVA Compared to SHAM, IUGR significantly reduced birth weight, restored to normal in IUGR+IGF-1 (1.12± .1vs 0.9± .1 vs 1.09± .1 g, p= .001). At 8 weeks, IUGR achieved mean body weight equivalent to SHAM and IUGR+IGF-1. By week 21, regardless of sex, IUGR significantly increased weight (obesity) compared to sham and IUGR+IGF-1 (fig A). Total fad pad weights were significantly higher in IUGR compared to SHAM but were restored to normal in IUGR+IGF1 (fig B). IUGR significantly increased fasting serum leptin, compared to Sham and restored to normal in IUGR+IGF1 ( .6± .4vs 5.7± 1.1 vs .8± .4 pg/ug, p= .01). No difference in food consumption amongst the groups Intra placental gene transfer of Ad hIGF1 corrects birth weight in IUGR mice model and attenuates the risk of postnatal obesity, This support the concept that in utero reprogramming of fetal predisposition to obesity is a novel approch to treatment of IUGR.

The coronary arteries of the Syrian hamster, Mesocricetus auratus (Waterhouse 1839)

1993 ◽  
Vol 175 (1) ◽  
pp. 53-57 ◽  
Author(s):  
V. Sans-Coma ◽  
J.M. Arqué ◽  
A.C. Durán ◽  
M. Cardo ◽  
B. Fernández ◽  
...  
Keyword(s):  
Coronary Arteries ◽  
Syrian Hamster ◽  
Mesocricetus Auratus

scholarly journals Hamster Polyomavirus Infection in a Pet Syrian Hamster (Mesocricetus auratus)

2001 ◽  
Vol 38 (4) ◽  
pp. 441-446 ◽  
Author(s):  
J. H. Simmons ◽  
L. K. Riley ◽  
C. L. Franklin ◽  
C. L. Besch-Williford
Keyword(s):  
Syrian Hamster ◽  
Mesocricetus Auratus ◽  
Hamster Polyomavirus
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