Effects of excessive dietary zinc or zinc/cadmium and tapeworm infection on the biochemical parameters in rats

2021 ◽  
Author(s):  
Vladislav Sloup ◽  
Ivana Jankovská ◽  
Magdalena Štolcová ◽  
Jan Magdálek ◽  
Veronika Karešová ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Dietary Zinc ◽  
Zinc Cadmium ◽  
Tapeworm Infection

Effects of dietary zinc supplementation on nutrient digestibility, haematological biochemical parameters and production performance in male sika deer (Cervus nippon)

2016 ◽  
Vol 56 (6) ◽  
pp. 997 ◽  
Author(s):  
Bao Kun ◽  
Sun Weili ◽  
Li Chunyi ◽  
Wang Kaiying ◽  
Li Zhipeng ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Sika Deer ◽  
Control Diet ◽  
Average Daily Gain ◽  
Cervus Nippon ◽  
Nutrient Digestibility ◽  
Production Performance ◽  
Control Group ◽  
Dietary Zinc ◽  
Group A

The purpose of the present study was to investigate the effects of dietary zinc (Zn) supplementation on antler growth, haematological biochemical parameters and nutrient digestibility in farmed male sika deer. Twenty-five 2-year-old growing male sika deer were randomly divided into five Groups (A, B, C, D and E; 5/group). Animals in Groups A, B, C, Dand E received 0, 5, 15, 40, 100 mg Zn/kg, respectively. Group A, without supplementation acted as a control. The treatment diets were the same basal diet supplemented with 5, 15, 40 and 100 mg Zn/kg (provided as Zn methionine), respectively. The results showed that the digestibility of dry matter (DM) and crude protein in Groups D and E were greater than that in Groups A, B and C (P < 0.05). Digestibility of neutral detergent fibre in Group E was higher than in the control group (P < 0.05). Plasma Zn concentrations were increased by Zn supplementation and were higher (P < 0.01) for the treatment groups supplemented with 15, 40 and 100 mg Zn/kg DM than for the control and 5 mg/kg Zn groups (P < 0.01). Faecal Zn content in Groups D and E was higher than that in Group A (P < 0.01). The content of albumin in plasma from Group E was greater than in the control and Groups B, C and D (P < 0.05). The concentrations of testosterone in plasma from Groups C, D and E were decreased (P < 0.05) compared with the control. The days between antler initiation and harvesting of deer in Groups D and E were decreased (P < 0.05). Average daily gain of fresh antler and dry antler of deer in Groups D and E was significantly higher than that in the control group (P < 0.05). In conclusion, a control diet containing 58.6 mg Zn/kg was inadequate for achieving optimal productivity for sika deer. The recommended Zn supplementation is from 76.7 to 99.0 mg/kg for 2-year-old male sika deer.

scholarly journals Exposure to Heavy Metal Elements May Significantly Increase Serum Prostate-Specific Antigen Levels With Overdosed Dietary Zinc

2021 ◽  
Author(s):  
Xiaoyue Chen ◽  
Chi Chen ◽  
Jukun Song ◽  
Heng Liu ◽  
Lingyue An ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Additive Model ◽  
Positive Association ◽  
Diagnostic Model ◽  
Dietary Zinc ◽  
Significant Positive Association ◽  
Zinc Intake ◽  
Zinc Cadmium ◽  
High Level

Abstract Background: Serum prostate-specific antigen (PSA) is a primary metric for diagnosis and prognosis of prostate cancer (PCa). Exposure to heavy metals, such as lead, cadmium, mercury, and zinc can impact PSA levels in PCa patients. However, it is unclear whether this effect also occurs in men without PCa, which may lead to the overdiagnosis of PCa.Method: Data on a total of 5,089 American men who had never been diagnosed with PCa were obtained from the National Health and Nutrition Examination Survey performed from 2003–2010. The relationship between serum PSA levels (dependent variable) and concentrations of lead (μmol/L), cadmium (nmol/L), and mercury (μmol/L) were investigated with dietary zinc intake being used as a potential modifier or covariate in a weighted linear regression model and a generalized additive model. A series of bootstrapping analyses were performed to evaluate sensitivity and specificity using these models. Results: Regression analyses suggested that, in general, lead, cadmium, or mercury did not show an association with PSA levels, which was consistent with the results of the bootstrapping analyses. However, in a subgroup of participants with a high level of dietary zinc intake (≥14.12 mg/day), a significant positive association between cadmium and serum PSA was identified (1.06, 95% CI, P=0.0268, P for interaction=0.0249).Conclusions: With high-level zinc intake, serum PSA levels may rise in PCa-free men as the exposure to cadmium increases, leading to a potential risk of an overdiagnosis of PCa and unnecessary treatment. Therefore, environmental variables should be factored in the current diagnostic model for PCa that is solely based on PSA measurements. Different criteria for PSA screening are necessary based on geographical variables. Further investigations are needed to uncover the biological and biochemical relationship between zinc, cadmium, and serum PSA levels to more precisely diagnose PCa.

Serum biochemical parameters in piglets after the application of essential oils

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
J Poracova ◽  
I Salamon ◽  
B Taylorova ◽  
M Zahatnanska ◽  
I Sutiakova
Keyword(s):  
Essential Oils ◽  
Biochemical Parameters ◽  
Serum Biochemical Parameters ◽  
Serum Biochemical
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