DNA methylation and histone acetylation are involved in Wnt10b expression during the secondary hair follicle cycle in Angora rabbits

2021 ◽  
Author(s):  
Liya Bai ◽  
Haitao Sun ◽  
Wenxue Jiang ◽  
Liping Yang ◽  
Gongyan Liu ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Histone Acetylation ◽  
Hair Follicle ◽  
Hair Follicle Cycle

The Tgf--/Bmp Co-Receptor Endoglin Is a Key Component of the Molecular Oscillator That Regulates the Hair Follicle Cycle

2018 ◽  
Author(s):  
Marra I. Calvo-SSnchez ◽  
Elisa Carrasco ◽  
Sandra Fernnndez-Martos ◽  
Gema Moreno ◽  
Carmelo Bernabeu ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Molecular Oscillator ◽  
Hair Follicle Cycle

scholarly journals Expression of miRNA-203 and its target gene in hair follicle cycle development of Cashmere goat

Cell Cycle ◽  
2021 ◽  
Vol 20 (2) ◽  
pp. 204-210
Author(s):  
Tao Ma ◽  
Jianyu Li ◽  
Jianping Li ◽  
Sufang Wu ◽  
Xiangba ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Target Gene ◽  
Cashmere Goat ◽  
Hair Follicle Cycle

DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers

2016 ◽  
Vol 373 (2) ◽  
pp. 185-192 ◽  
Author(s):  
Ching-Yu Yen ◽  
Hurng-Wern Huang ◽  
Chih-Wen Shu ◽  
Ming-Feng Hou ◽  
Shyng-Shiou F. Yuan ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Histone Acetylation ◽  
Therapeutic Approach ◽  
Epigenetic Modifications

scholarly journals Integrated analysis of coding genes and non-coding RNAs during hair follicle cycle of cashmere goat (Capra hircus)

BMC Genomics ◽  
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Shanhe Wang ◽  
Wei Ge ◽  
Zhixin Luo ◽  
Yang Guo ◽  
Beilei Jiao ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Capra Hircus ◽  
Integrated Analysis ◽  
Cashmere Goat ◽  
Non Coding Rnas ◽  
Hair Follicle Cycle

Selection and validation of suitable reference genes in skin tissue of Liaoning cashmere goat during hair follicle cycle

2014 ◽  
Vol 161 ◽  
pp. 28-35 ◽  
Author(s):  
Wen L. Bai ◽  
Rong H. Yin ◽  
Rong L. Yin ◽  
Wu Q. Jiang ◽  
Jiao J. Wang ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Reference Genes ◽  
Skin Tissue ◽  
Cashmere Goat ◽  
Hair Follicle Cycle ◽  
Suitable Reference ◽  
Liaoning Cashmere Goat

scholarly journals A Role for Global DNA Methylation Level and IL2 Expression in the Transition From Acute to Chronic Low Back Pain

2021 ◽  
Vol 2 ◽  
Author(s):  
Olivia C. Eller ◽  
Nicole Glidden ◽  
Brittany Knight ◽  
Noelle McKearney ◽  
Mallory Perry ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Low Back Pain ◽  
Back Pain ◽  
Histone Acetylation ◽  
Mrna Expression ◽  
Interleukin 2 ◽  
Global Dna Methylation ◽  
Low Back ◽  
Recent Onset ◽  
Acute Low Back Pain

Objectives: The transition from acute low back pain (aLBP) to chronic LBP (cLBP) results from a variety of factors, including epigenetic modifications of DNA. The aim of this study was to (1) compare global DNA (gDNA) methylation and histone acetylation at LBP onset between the aLBP and cLBP participants, (2) compare mRNA expression of genes with known roles in the transduction, maintenance, and/or modulation of pain between the aLBP and cLBP participants, (3) compare somatosensory function and pain ratings in our participants, and (4) determine if the aforementioned measurements were associated.Methods: A total of 220 participants were recruited for this prospective observational study following recent onset of an episode of LBP. We retained 45 individuals whose gDNA was of sufficient quality for analysis. The final sample included 14 participants whose pain resolved within 6 weeks of onset (aLBP),15 participants that reported pain for 6 months (cLBP), and 16 healthy controls. Participants were subjected to quantitative sensory testing (QST), blood was drawn via venipuncture, gDNA isolated, and global DNA methylation and histone acetylation, as well as mRNA expression of 84 candidate genes, were measured.Results: Individuals that develop cLBP display multimodal somatosensory hypersensitivity relative to aLBP participants. cLBP participants also had significantly lower global DNA methylation, which was negatively correlated with interleukin-2 (IL2) mRNA expression.Discussion: cLBP is characterized by somatosensory hypersensitivity, lower global DNA methylation, and higher IL2 expression level compared to those whose pain will resolve quickly (aLBP). These results suggest potential diagnostic and therapeutic relevance for global DNA methylation and IL2 expression in the pathology underlying the transition from acute to chronic LBP.

Effects of Scriptaid on the Histone Acetylation, DNA Methylation and Development of Buffalo Somatic Cell Nuclear Transfer Embryos

2015 ◽  
Vol 17 (5) ◽  
pp. 404-414 ◽  
Author(s):  
Hongliang Sun ◽  
Fenghua Lu ◽  
Peng Zhu ◽  
Xiaohua Liu ◽  
Mingming Tian ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Somatic Cell ◽  
Histone Acetylation ◽  
Somatic Cell Nuclear Transfer ◽  
Nuclear Transfer
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